THE EFFECTS OF INTRAVENOUS INFUSION OF LYSINE, LYSINE PLUS METHIONINE OR CARNITINE ON PLASMA AMINO ACIDS AND MILK PRODUCTION OF DAIRY COWS

1977 ◽  
Vol 57 (1) ◽  
pp. 101-109 ◽  
Author(s):  
J. D. ERFLE ◽  
L. J. FISHER

Four lactating Holstein cows were each infused intravenously for periods of up to 9 days with solutions of L-lysine (15 g/day), L-lysine plus D,L-methionine (15 + 10 g/day) D,L-carnitine (20 g/day) or physiological saline. The cows were fed a ration of 2 kg chopped hay (14.8% crude protein), corn silage ad libitum (8.0% crude protein) and a concentrate mixture (16.5% crude protein) (1 kg/3 kg milk). Daily digestible protein intake was 1.85 kg/cow or 87% of calculated (National Academy of Sciences – National Research Council) requirements. There was no significant effect of infusion treatment on intake of corn silage, milk yield and composition or digestibility of the ration. The efficiencies of conversion of dietary protein to milk protein were 38.4, 38.6, 36.6 and 37.8% and nitrogen balances were 6, −2, 8 and 5 g/day for saline, lysine, lysine plus methionine and carnitine infusions. The concentration of carnitine in the milk was greater when carnitine was infused but was unaffected by the infusion of lysine and methionine. Plasma lysine and methionine were increased when these amino acids were infused. On the basis of plasma amino acid patterns it was concluded that methionine, lysine and threonine were possibly the most limiting amino acids under the conditions of this experiment and that in combination with a less than adequate energy intake (i.e. 87% of calculated requirements), infusion of lysine and methionine failed to give a response in production.

1975 ◽  
Vol 55 (3) ◽  
pp. 347-351 ◽  
Author(s):  
E. J. OROK ◽  
J. P. BOWLAND

Plasma urea measurements were taken in an experiment designed to compare rapeseed (RSM), peanut (PNM) and soybean meals (SBM) as protein supplements for growing pigs (5–15 wk of age, 7.0–26.7 kg liveweight). Eight diets were formulated to meet National Academy of Sciences–National Research Council (1973) requirements of 10–20 kg pigs for crude protein and digestible energy. After 8–9 wk on test and following 24 h starvation, plasma urea concentrations of individual pigs were measured at 0, 1, 2, 3, 4, 5 and 7 h postprandial, the 0 h measurements being those taken just before refeeding. Plasma volumes of individual pigs were predicted from an equation. From these volumes and plasma urea concentrations, the increase in plasma urea output was expressed as a percentage of nitrogen (N) ingested on the morning of blood sampling (U/N%) for postprandial intervals of 0–3 h, 0–7 h and 4–7 h. Plasma urea concentration showed no consistent inverse relationship to dietary protein quality. However, U/N% for the period 0–7 h postprandial ranked diets in the same order as average daily liveweight gain. Under conditions of varied feed intake this procedure of relating the increase in plasma urea output to grams N ingested (%) offers a possible method for evaluating protein supplements.


2003 ◽  
Vol 83 (2) ◽  
pp. 205-211 ◽  
Author(s):  
A. Fortin ◽  
E. J. Clowes ◽  
A. L. Schaefer

This study was conducted to determine whether feeding gilts (1) at or above their National Academy of Sciences-National Research Council (NAS-NRC 1998) requirements during gestation, and (2) to lose a moderate (~10%) or large (~17%) amount of maternal protein during lactation had a residual effect on their progeny’s growth, carcass characteristics and pork quality at market weight. From each litter, the heaviest and lightest barrows and gilts were selected. The progeny of gilts fed above their requirements during gestation, and those that lost the least body protein during lactation were heavier at weaning; +0.3 kg (P < 0.05) and +0.5 kg (P = 0.01), respectively. However, these liveweight differences, which were associated with the gestation and lactation effects, were no longer evident (P > 0.05) at day 35 or 85 post-weaning. But at slaughter, these animals had thinner (P < 0.01) fat thickness and higher (P < 0.05) predicted salable meat yield. Independently of the gestation and lactation treatments, and compared to the low-weaning-weight pigs, the high- weaning-weight pigs maintained their weight advantage (P < 0.01 at day 35 (+ 2.8 kg) and day 85 (+ 5.4 kg) post-weaning), took 4.5 fewer days (P < 0.01) to reach market weight, but had similar (P > 0.05) carcass characteristics and pork quality. Key words: Gilts, gestational and lactational protein, litter, growth, carcass characteristics and meat quality


2019 ◽  
Vol 22 (6) ◽  
pp. 757-760 ◽  
Author(s):  
Margaret Gatz ◽  
Brenda L. Plassman ◽  
Caroline M. Tanner ◽  
Samuel M. Goldman ◽  
Gary E. Swan ◽  
...  

AbstractThe National Academy of Sciences-National Research Council (NAS-NRC) Twin Registry is one of the oldest, national population-based twin registries in the USA. It comprises 15,924 White male twin pairs born in the years 1917–1927 (N = 31.848), both of whom served in the armed forces, chiefly during World War II. This article updates activities in this registry since the most recent report in Twin Research and Human Genetics (Page, 2006). Records-based data include information from enlistment charts and Veterans Administration data linkages. There have been three major epidemiologic questionnaires and an education and earnings survey. Separate data collection efforts with the NAS-NRC registry include the National Heart, Lung, and Blood Institute (NHLBI) subsample, the Duke Twins Study of Memory in Aging and a clinically based study of Parkinson’s disease. Progress has been made on consolidating the various data holdings of the NAS-NRC Twin Registry. Data that had been available through the National Academy of Sciences are now freely available through National Archive of Computerized Data on Aging (NACDA).


2021 ◽  
Vol 7 ◽  
Author(s):  
Tammy J. Owens ◽  
Andrea J. Fascetti ◽  
C. Christopher Calvert ◽  
Jennifer A. Larsen

Whole-prey diets for exotic feline species are common, and this practice has also increased in popularity for domestic cats. However, prior analyses of prey indicate possible essential amino acid inadequacy, and dilated cardiomyopathy from taurine deficiency was reported in cats fed whole ground rabbit. Crude protein, body water, and amino acid concentrations were evaluated in fresh and frozen ground rabbits with (n=10) or without (n = 10) gastrointestinal tracts. Amino acids were greater in fresh samples without gastrointestinal tracts (p &lt; 0.05) except taurine, glycine, and cysteine. When normalized for protein content, only glutamate, alanine, methionine, isoleucine, tyrosine, lysine, histidine, and arginine were greater in fresh rabbits without gastrointestinal tracts (g/16 g N basis; p &lt; 0.05). Freezing at −18°C for 30 days had no effect on crude protein or body water content. After freezing, only methionine was lower and only proline was higher when gastrointestinal tracts were omitted (g/16 g N basis; p &lt; 0.05). Regardless, all essential amino acids except taurine exceeded Association of American Feed Control Officials and National Research Council nutrient recommendations for all feline life stages. In contrast, there was minimal impact of treatment on taurine concentrations. However, although feline taurine requirements for prey and other raw or fresh food diets remain undefined, none of the rabbit samples met any recommendation for taurine concentrations for commercial canned or dry extruded diets, ranging from 20 to 90% of the minimum values. Taurine supplementation is recommended when feeding rabbit to cats. Determination of taurine requirements of cats fed whole-prey diets is warranted.


1989 ◽  
Vol 33 (10) ◽  
pp. 568-570
Author(s):  
Harold P. Van Cott

The Committee on Human Factors, a standing committee of the National Academy of Sciences/National Research Council (NAS/NRC), advises its sustaining sponsors and other requesting organizations on issues involved in the design of socio-technical systems and on the research and methods needed to help enhance their operability and safety. This paper describes the origins, purposes, operations and program of the committee and emphasizes the special attributes of this and other NAS/NRC commtittees.


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