scholarly journals THE EFFECT OF ESTRADIOL AND TESTOSTERONE INJECTIONS AND THYROIDECTOMY ON MUSCLE FIBRE DIAMETERS AND LIVE WEIGHT GAIN IN YEARLING SHEEP

1959 ◽  
Vol 39 (2) ◽  
pp. 202-208 ◽  
Author(s):  
M. A. MacDonald ◽  
S. B. Slen

In this study effects of estradiol and testosterone injections and thyroidectomy on muscle fibre diameters of ewe and wether yearlings were determined. Forty-eight sheep, half of which were ewes and half wethers, were subdivided into estradiol, testosterone, and control groups containing equal numbers of each sex. Half of the animals within each sex group and treatment group were thyroidectomized. Biweekly rates of intramuscular injection of estradiol and testosterone were 5 mg. and 175 mg., respectively. All animals received the same amount of feed per day throughout a 195-day experimental period.Live weight gain, carcass weight, and percentage dry matter of m. longissimus dorsi tissue were not influenced significantly by hormone injection, thyroidectomy, or sex. Estradiol injections significantly increased (p <.01) muscle fibre diameters of thyroidectomized ewes and wethers but the animals with thyroids were unaffected. Testosterone injections failed to affect muscle fibre diameters. Differences in muscle fibre diameters could not be explained by differences in percentage moisture content of muscle tissue.

1978 ◽  
Vol 40 (2) ◽  
pp. 193-203 ◽  
Author(s):  
G. M. J. Horton ◽  
W. L. Jenkins ◽  
Rosemarie Rettenmaier

1. Four methods of vitamin E and selenium supplementation were evaluated using thirty-nine pregnant ewe-lambs fed on a ration containing 0.043 mg Se/kg and 25 mg vitamin E/kg. Treatments were control, fortified mineral mix (ESe salt) (300 mg vitamin E, 3 mg Se), ruminal Se pellets (505 mg Se), drench (300 mg vitamin E, 3 mg Se) and intramuscular injection (600 mg vitamin E, 3 mg Se). Only ewes were supplemented, commencing approximately 50 d before parturition.2. Birth weights were similar for all treatments and live-weight gains of lambs to 56 d of age were improved in all supplemented groups (P < 0.05). There were no clinical cases of nutritional muscular dystrophy.3. Se concentrations in whole blood were more than doubled in both lambs and ewes drenched or injected; responses to ESe salt and pellets were much smaller.4. Plasma tocopherol levels were increased in injected dams and their lambs (P < 0.001).5. Haemoglobin concentration and erythrocyte counts were significantly higher (P < 0.01) in control ewes and lambs than in treated lambs.6. Lactate dehydrogenase (EC 1.1.1.27), creatine kinase (EC 2.7.3.2) and aspartate aminotransferase (EC 2.6.1.1) activities were increased in lambs from control, ESe salt and pellet groups (P < 0.001). Glutathione peroxidase (EC 1.1.1.1.9) activity responded to Se supplementation in both ewes and their lambs (P < 0.001) and the response was highest in the injected group, followed, in order, by the drench, pellet, ESe salt and control groups.7. These studies indicated that in terms of the haematological and blood chemistry changes investigated, the intramuscular injection was most effective, followed by the oral drench. Ruminal pellets and fortified salt were less satisfactory.


2020 ◽  
Vol 14 (4) ◽  
pp. 99-103
Author(s):  
V. I. Kolesnikov

The purpose of the research is studying the efficacy of Eprimek (Eprinomectin) against gastrointestinal nematodes in sheep.Materials and methods. A commercial experiment to study the antiparasitic efficacy of Eprimek was carried out in June 2020 on 300 lambs of the North Caucasian breed in a private flock of Filimonovskaya Village, Izobilnensky District, the Stavropol Territory, which were divided into two groups. The experimental group of lambs (290 animals) was injected Eprimek subcutaneously at the earset at a dose of 1 ml/50 kg of live weight (10 mg of Eprinomectin in 1 ml), and 10 lambs were not treated; they were used as control. We collected feces from the lambs of the experimental and control groups before administration of the drugs and after 15 and 30 days. Fecal samples were examined by the flotation technique with a saturated solution of ammonium nitrate with counting nematode eggs in 1 g of feces. The results were processed statistically.Results and discussion. Eprimek showed a decrease in the number of excreted helminth eggs from 225.1±28.2 to 4.1±2.3 in production environment at a dose of 1 ml/50 kg of live weight, according to coprological studies on the 15th day after treatment in the experimental group of lambs. The efficacy was 98.2%, and 70% of the animals were free from the infection. The intensity of infection of the control lambs by gastrointestinal nematodes was 131–151 eggs per 1 g of feces at 100% prevalence.


1975 ◽  
Vol 84 (2) ◽  
pp. 353-364 ◽  
Author(s):  
C. Thomas ◽  
J. M. Wilkinson ◽  
J. C. Tayler

SUMMARYFifty-four British Friesian castrated male calves, initially 3, 6 or 9 months of age (107, 180 and 249 kg initial live weight, respectively), were individually fed for 83 days on maize silage (27·9% dry matter (D.M.), 10·7% crude protein in D.M.), offeredad libitum. Silage was offered either alone or supplemented with cobs of dried lucerne (21% of total D.M. intake). Three levels of urea (0, 1 and 2% of silage D.M.) were added to the silage before feeding.Total D.M. intakes averaged 23·0, 23·4 and 21·6 g/kg live weight (LW) for the 3-, 6- and 9-month-old animals, respectively. Addition of urea increased silage intake by 11% in the 6-month-old group but there was little effect in the 3- and 9-month-old groups. Lucerne supplementation reduced silage D.M. intake from 22·0 to 18·4 g/kg LW (P< 0·001) and increased total D.M. intake by 1·4 g/kg LW (P< 0·001).Live-weight gain (LWG) of the cattle fed on silage alone increased (P< 0·001) with increasing age of animal. The main effect of urea was to elevate (P< 0·001) LWG from an average of 0·79 (no urea) to 0·94 kg/head/day (2% urea). However, it appeared that most of this effect was confined to the 6-month-old group. The effect of lucerne on LWG decreased with increasing age of animal (P< 0·001). Inclusion of lucerne in the diet significantly reduced the response to urea (P< 0·05).Feed conversion efficiency (LWG/100 Mcal DE intake) decreased (P< 0·01) with increasing age of animal but increased with urea addition from an average of 4·7 (no urea) to 5·3 kg LWG/100 Meal DE intake (2% urea). The response to lucerne supplementation in terms of efficiency was greatest in the 3-month-old group and thereafter declined markedly with increasing age of animal.The results of this experiment indicated that cattle older than 6 months of age (180 kg LW) could achieve a rate of growth of 1·0 kg/head/day on maize silage supplemented solely with urea, but that younger animals required supplementary lucerne to support a high rate of live-weight gain.


Author(s):  
R.J. Milner ◽  
F. Reyers ◽  
J.H. Taylor ◽  
J.S. Van den Berg

A clinical trial was designed to evaluate the effects of diminazene aceturate and its stabiliser antipyrine on serum pseudocholinesterase (PChE) and red blood cell acetylcholinesterase (RBC AChE) in dogs with babesiosis. The trial was conducted on naturally occurring, uncomplicated cases of babesiosis (n = 20) that were randomly allocated to groups receiving a standard therapeutic dose of diminazene aceturate with antipyrine stabiliser (n = 10) or antipyrine alone (n = 10). Blood was drawn immediately before and every 15 minutes for 1 hour after treatment. Plasma PChE showed a 4 % decrease between 0 and 60 min within the treatment group (p < 0.05). No statistically significant differences were found between the treatment and control groups at any of the time intervals for PChE. There was an increase in RBC AChE activity at 15 min in the treatment group (p < 0.05). No significant differences were found between the treatment and control groups at any time interval for RBC AChE. In view of the difference in PChE, samples from additional, new cases (n = 10) of canine babesiosis were collected to identify the affect of the drug over 12 hours. No significant depression was identified over this time interval. The results suggests that the underlying mechanism in producing side-effects, when they do occur, is unlikely to be through cholinesterase depression.


Author(s):  
K. I. Khidirov ◽  
◽  
G. J. Kutlieva ◽  
B. I. Turaeva ◽  
N. A. Elova ◽  
...  

Research has been carried out to study the influence of "ProBioKorm Uz", a biologically active feed additive, on the development and physiological characteristics of rabbits of ‘New Zealand’ breed. During the experiment, 2 experimental and a control groups were formed. Adding "ProBioKorm Uz" to the main feed at the rate of 1% and 2% had an increase in experimental group rabbits’ live weight. Average live weight of them was higher by 5,7 %-3.8% than in the control group. Feed units composed 1.59%, dry matter 0.56 kg (3.61%) and crude protein 0.11 kg (3.59%) compared with the control group. Rabbits of experimental groups had higher indicators of erythrocytes concentration by 0.34-1.00 1012/l (10.34-19.53%), leukocytes - by 0.370-0.46 109/l (5.66-8, 06%), as well as a high level of hemoglobin by 7.42-11.08 g/l (6.81-10.08%) and total protein - by 2.40-4.48 (3.64-6, 42%).


2021 ◽  
Vol 1 (2) ◽  
pp. 55-67
Author(s):  
Werna Nontji ◽  
Dwi Kartika Sari ◽  
Sitti Maria Ulfa ◽  
Syafruddin Syarif ◽  
Inez Vravty Lestari ◽  
...  

Background: Educating mothers during their postpartum period could potentially help them to overcome some important phases after giving birth. The process of education is evaluated based on the mothers’ knowledge about their independent self-care. Independency is an activity that is started individually and is done based on self-capability. The independency in the postpartum care is not only important to decrease the mother’s mortality and morbidity rate, but it is also crucial to strengthen and improve the post-partum mother’s healthy behavior during the perineal care. Providing education using Android-based application called BUBI Care could be potential to facilitate a more dynamic transfer of knowledge to the postpartum mothers.Aims: To analyze the knowledge, skills, and independence of primipara postpartum mothers in independent perineal care before and after accessing BUBI Care app. Research Method: employing quasi experimental research with pre-test and post-test design with control group design. The sample for this research were 19 pregnant mothers TM III (pregnancy age of ? 38 weeks) on each group. The treatment group was educated using BUBI Care Android app that was conducted at one of Public Health Center. The control group was educated without BUBI Care that was conducted at a Midwife Practice Clinic. The research was conducted on September to October 2020. Study Result: According to the Wilcoxon test, there was a difference in the pre-test knowledge of the treatment and control groups with the similar median of 53 and p-value of 0.666, the treatment group showed their scores improved to 80 on the post-test while the control group stayed at 53 with the p-value of 0.000. It means that BUBI Care app education influences the post-test. On the other hand, the perineal care skill saw a difference between the intervention and control groups. The intervention group had a mean of 70.05 and 56.68 for the control group with the p-value of 0.002 which means that there was an influence from the BUBI Care app education. Additionally, Mann Whitney test showed that the intervention group had a mean score of 78.95, but the control group only had 49.26, the total difference between the two are 29.69 with the p-value of 0.000. It can be concluded that there is a significance in difference in the independency rate from the provision of BUBI Care Android app education.Conclusion:  there is a significance effect on the intervention group in terms of Android based usage.


2021 ◽  
Vol 32 (1) ◽  
pp. 88-93 ◽  
Author(s):  
O. A. Fasae ◽  
J. A. Alokan ◽  
G. E. Onibi

Four Yankasa sheep, weighing between 19 and 24kg live weight and with age range between 15-24 months were used in a metabolism study to determine the intake and the digestibility of Leucaena leucocephala leaf residue (LLLR) while diets B, C and D had 15, 30 and 45% LLLR inclusion respectively. Dry matter and dietary crude protein intake by trhe environmental animals decreased with increasing level of LLLR inclusion in the diets, although these values were not significant (P>0.05). Also, digestion rates for dry matter and nutrients decreased as protein level of the diets decreased but variation were not significant (P<0.05). Inclusion of 15% LLLR in the dust produced the best weight gain, though this was significantly (P>0.05) different from other treatments. None of the animals developed any health problem and none was underfed as they all recorded an increase in weight. The diet with 15% LLLR produced performance similar to the control both in nutrient intake and weight gain


1995 ◽  
Vol 12 (4) ◽  
pp. 161-163 ◽  
Author(s):  
Lyn Jensen ◽  
Ellen Logan ◽  
Oliver Finney ◽  
Stephen Lowry ◽  
Martyn Smith ◽  
...  

We conducted 215 evaluations for plaque, stain, and calculus in 120 dogs at two research sites. Dogs were balanced in groups of five according to baseline plaque index scores; groups were randomly assigned to treatment or control dietary regimens. Dental cleanings were done on Day 0. Dogs in the treatment group were fed a food formulated to reduce accumulation of plaque, stain, and calculus. Control group dogs were fed a commercially available dry dog food. No other foods, treats, or snacks were given to either group. We graded 22 teeth for plaque accumulation on Day 7 and for stain and calculus accumulation on Day 21. Six trials were conducted and the results reported as a combined mean for all treatment and control groups. Dogs fed the treatment food had significantly less plaque, stain, and calculus accumulation (p=0.001) than dogs fed the control food. Plaque, stain, and calculus accumulation can be reduced by dietary means.


2020 ◽  
Vol 187 (8) ◽  
pp. e58-e58
Author(s):  
Victry Fredley ◽  
Rachael Kreisler ◽  
Kirk Miller

BackgroundStress-induced anorexia is common in cats. While medications are available to stimulate appetite, many require oral administration, have delayed onset-of-action or cause adverse side effects. The aim of this study was to determine whether cats diagnosed with stress-induced anorexia given a subhypnotic dose of intravenous propofol would have increased short-term appetite as compared to those given placebo.MethodsAnorexic shelter cats received either 1 mg/kg propofol or 1 mL saline placebo and then presented with various commercial cat foods. Grams of food consumed was measured at 15 and 30 min, and total grams compared between treatment and control groups using the Wilcoxon rank-sum test. 12 cats were enrolled, with six cats randomly assigned to each group.ResultsThe median amount consumed by the treatment group was 31 g (range: 0–72), with the median for the four cats (67 per cent) who consumed food being 45 g (range: 26–72), or 49 per cent of their daily maintenance calorie requirement. The median amount consumed by control cats was 0 g (range: 0–5), with one cat consuming food. Total grams consumed was different between treatment and control groups (P=0.05).ConclusionA subhypnotic dose of intravenous propofol increased appetite in cats with stress-induced anorexia for a 30 min period.


1969 ◽  
Vol 11 (1) ◽  
pp. 19-28 ◽  
Author(s):  
D. G. Miles ◽  
R. J. K. Walters ◽  
E. M. Evans

SUMMARYA series of animal feeding trials was designed to determine differences between grasses in dry-matter intake and animal live-weight gain, with a view to indicating better selection criteria for improving the feeding value of herbage.Wide differences were demonstrated in feed intake and live-weight gain between single-variety grass feeds at similar levels of digestibility.S.37 cocksfoot gave consistently good and S.51 timothy, consistently poor responses.Supplementation of grass feeds with red clover frequently resulted in marked improvement in feed intake and animal performance.


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