scholarly journals Comparison of osteogenic potential of poly-ether-ether-ketone with titanium-coated poly-ether-ether-ketone and titanium-blended poly-ether-ether-ketone: An in vitro study

2017 ◽  
Vol 17 (2) ◽  
pp. 167 ◽  
Author(s):  
TAnjan Kumar ◽  
JBrintha Jei ◽  
B Muthukumar
Author(s):  
Antoine Berbéri ◽  
Joseph Sabbagh ◽  
Rita Bou Assaf ◽  
Michella Ghassibe-Sabbagh ◽  
Fatima Al-Nemer ◽  
...  

2017 ◽  
Vol 7 (8) ◽  
pp. 662-670 ◽  
Author(s):  
Nayansi Jha ◽  
Jin Sung Choi ◽  
Ji Hye Kim ◽  
Ranju Jung ◽  
Eun Ha Choi ◽  
...  

2016 ◽  
Vol 21 (5) ◽  
pp. 1599-1609 ◽  
Author(s):  
Antoine Berbéri ◽  
Fatima Al-Nemer ◽  
Eva Hamade ◽  
Ziad Noujeim ◽  
Bassam Badran ◽  
...  

2015 ◽  
Vol 231 (3) ◽  
pp. 607-612 ◽  
Author(s):  
Gabriele Ceccarelli ◽  
Antonio Graziano ◽  
Laura Benedetti ◽  
Marcello Imbriani ◽  
Federica Romano ◽  
...  

Author(s):  
K H Tan ◽  
C K Chua ◽  
K F Leong ◽  
M W Naing ◽  
C M Cheah

The ability to have precise control over porosity, scaffold shape, and internal pore architecture is critical in tissue engineering. For anchorage-dependent cells, the presence of three-dimensional scaffolds with interconnected pore networks is crucial to aid in the proliferation and reorganization of cells. This research explored the potential of rapid prototyping techniques such as selective laser sintering to fabricate solvent-free porous composite polymeric scaffolds comprising of different blends of poly(ether-ether-ketone) (PEEK) and hydroxyapatite (HA). The architecture of the scaffolds was created with a scaffold library of cellular units and a corresponding algorithm to generate the structure. Test specimens were produced and characterized by varying the weight percentage, starting with 10 wt% HA to 40 wt% HA, of physically mixed PEEK-HA powder blends. Characterization analyses including porosity, microstructure, composition of the scaffolds, bioactivity, and in vitro cell viability of the scaffolds were conducted. The results obtained showed a promising approach in fabricating scaffolds which can produce controlled microarchitecture and higher consistency.


2020 ◽  
Vol 10 (19) ◽  
pp. 6713
Author(s):  
Damiano Pasqualini ◽  
Allegra Comba ◽  
Laura Annaratone ◽  
Virginia Mola ◽  
Mario Alovisi ◽  
...  

Recently, pre-mixed bioceramics in fast set formulations have been increasingly utilized in clinical practice as an alternative to mineral trioxide aggregate (MTA) for their shorter setting time and better handling properties. However, the impact on their osteogenic potential, due to modifications in chemical composition to promote a fast setting, is still unclear. This molecular and in vitro study compared the osteogenic potential of root repairing material putty fast set (FSP) with root-repairing material putty (RRMPU), root-repairing material paste (RRMPA), Biodentine™ and MTA. The null hypothesis tested was that there are no differences among the tricalcium silicate materials in terms of osteogenic potential. Standardized discs were cultured with MG-63 human osteoblastic-like cells to assess biocompatibility, the activity of alkaline phosphatase (ALP) and osteogenic potential. Biocompatibility was evaluated at baseline and after 24 and 48 h. Osteogenic differentiation was assessed after 15 days. Data were analyzed with one-way ANOVAs and Tukey’s post-hoc test (p < 0.05). All materials showed biocompatibility and bioactivity. ALP activity, which induces mineral nodule deposition, increased in all the cements tested, with a significant increase in RRMPU (p < 0.001) and FSP (p < 0.001) samples versus MTA. In vitro mineralization was significantly increased for RRMPU (p < 0.0001), FSP (p = 0.00012) and Biodentine™ (p < 0.0001) versus MTA. The bioceramics tested showed higher levels of biocompatibility and bioactivity than MTA; a higher capacity for mineralization was observed with RRMPU and FSP versus MTA.


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