scholarly journals Osteogenic Potential of Fast Set Bioceramic Cements: Molecular and In Vitro Study

2020 ◽  
Vol 10 (19) ◽  
pp. 6713
Author(s):  
Damiano Pasqualini ◽  
Allegra Comba ◽  
Laura Annaratone ◽  
Virginia Mola ◽  
Mario Alovisi ◽  
...  
Keyword(s):  
Setting Time ◽  
Mineral Trioxide Aggregate ◽  
In Vitro Study ◽  
Tricalcium Silicate ◽  
Vitro Study ◽  
Osteogenic Potential ◽  
In Vitro Mineralization ◽  
Post Hoc ◽  
The Impact

Recently, pre-mixed bioceramics in fast set formulations have been increasingly utilized in clinical practice as an alternative to mineral trioxide aggregate (MTA) for their shorter setting time and better handling properties. However, the impact on their osteogenic potential, due to modifications in chemical composition to promote a fast setting, is still unclear. This molecular and in vitro study compared the osteogenic potential of root repairing material putty fast set (FSP) with root-repairing material putty (RRMPU), root-repairing material paste (RRMPA), Biodentine™ and MTA. The null hypothesis tested was that there are no differences among the tricalcium silicate materials in terms of osteogenic potential. Standardized discs were cultured with MG-63 human osteoblastic-like cells to assess biocompatibility, the activity of alkaline phosphatase (ALP) and osteogenic potential. Biocompatibility was evaluated at baseline and after 24 and 48 h. Osteogenic differentiation was assessed after 15 days. Data were analyzed with one-way ANOVAs and Tukey’s post-hoc test (p < 0.05). All materials showed biocompatibility and bioactivity. ALP activity, which induces mineral nodule deposition, increased in all the cements tested, with a significant increase in RRMPU (p < 0.001) and FSP (p < 0.001) samples versus MTA. In vitro mineralization was significantly increased for RRMPU (p < 0.0001), FSP (p = 0.00012) and Biodentine™ (p < 0.0001) versus MTA. The bioceramics tested showed higher levels of biocompatibility and bioactivity than MTA; a higher capacity for mineralization was observed with RRMPU and FSP versus MTA.

scholarly journals The effect of 5% NaOCl and 17% EDTA, at 24hrs and 8days, on the microhardness of MTA, Biodentine and Pozzolan cement: An in- vitro study.

2021 ◽  
Vol 6 (3) ◽  
pp. 16-21
Author(s):  
Sarita Dasani ◽  
Baljeet S Hora ◽  
Rucheeta S Ajmera ◽  
Brijesh Gupta ◽  
Yadnesh Dondulkar ◽  
...  
Keyword(s):  
Mineral Trioxide Aggregate ◽  
In Vitro Study ◽  
Vitro Study ◽  
Time Points ◽  
Post Hoc ◽  
Vicker’S Microhardness ◽  
One Way Anova

Aim & Objectives: The aim of this study was to evaluate the effects, at 24 h and 8 days, of 5% NaOCl and 17% EDTA on the Vicker’s microhardness of Mineral Trioxide Aggregate(MTA Angelus) (MTAA), Biodentine(Septodont, Saint Maur des Fosse’s France) and Pozzolan based endodontic cement named Endocem MTA(Maruchi, Wonju, Korea). Materials and method: Sixty samples of MTAA, Biodentine and Endocem MTA were tested for baseline microhardness at 24 h. They were divided into 12 subgroups (5% NaOCl or 17% EDTA, 24 h and 5% NaOCl or 17% EDTA at 8 days) and microhardness was evaluated at different time points. Results were recorded and analysed statistically via one-way ANOVA and Tukey’s post hoc  test. Results: MTAA had a higher baseline microhardness than both biodentine and Endocem MTA. At 24 hrs, the microhardness of all the materials was reduced by NaOCl and EDTA. At 8 days, NaOCl reduced the microhardness of MTA but that of Biodentine and Endocem MTA was increased. EDTA at 8 days, reduced the microhardness of both MTAA and Biodentine but an increase was seen with Endocem MTA. Conclusion: Changes in microhardness of MTAA, Biodentine and Pozzolan cement(Endocem MTA) were associated with the time for which the materials are allowed to set as well as the irrigating agent used,.  

scholarly journals EVALUATION OF SETTING TIME OF MINERAL TRIOXIDE AGGREGATE AND BIODENTINE IN THE PRESENCE OF HUMAN BLOOD AND MINIMAL ESSENTIAL MEDIA - AN IN VITRO STUDY

2017 ◽  
Vol 4 (94) ◽  
pp. 5849-5852
Author(s):  
Gopi Krishna Reddy Moosani ◽  
Chandra Sekhar Manduri ◽  
Nagalakshmi Reddy Sampathi ◽  
Datta Sai Kiran Katta ◽  
Raghavalli Medepalli ◽  
...  
Keyword(s):  
Human Blood ◽  
Setting Time ◽  
Mineral Trioxide Aggregate ◽  
In Vitro Study ◽  
Vitro Study

Comparing the osteogenic potential of schneiderian membrane and dental pulp mesenchymal stem cells: an in vitro study

2021 ◽  
Author(s):  
Antoine Berbéri ◽  
Joseph Sabbagh ◽  
Rita Bou Assaf ◽  
Michella Ghassibe-Sabbagh ◽  
Fatima Al-Nemer ◽  
...  
Keyword(s):  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Dental Pulp ◽  
In Vitro Study ◽  
Vitro Study ◽  
Osteogenic Potential ◽  
Schneiderian Membrane

The Effect of Mineral Trioxide Aggregate on the Mineralization Ability of Rat Dental Pulp Cells: An In Vitro Study

2008 ◽  
Vol 34 (9) ◽  
pp. 1057-1060 ◽  
Author(s):  
Yoshiyuki Yasuda ◽  
Masafumi Ogawa ◽  
Toshiya Arakawa ◽  
Tomoko Kadowaki ◽  
Takashi Saito
Keyword(s):  
Dental Pulp ◽  
Mineral Trioxide Aggregate ◽  
In Vitro Study ◽  
Vitro Study ◽  
Dental Pulp Cells ◽  
Pulp Cells

The impact of stent design on the structural mechanics of the crossing Y-stent: an in vitro study

2014 ◽  
Vol 56 (8) ◽  
pp. 655-659 ◽  
Author(s):  
Chang-Young Lee ◽  
Seong-Ho Park ◽  
Chang-Hyun Kim ◽  
Goetz Benndorf
Keyword(s):  
In Vitro Study ◽  
Structural Mechanics ◽  
Vitro Study ◽  
Stent Design ◽  
The Impact
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