scholarly journals Linear immunoglobulin A bullous dermatosis with severe ocular sequela

2020 ◽  
Vol 38 (1) ◽  
pp. 48
Author(s):  
Wen-Hung Chung ◽  
Meng-Han Shen ◽  
Tseng-Tong Kuo
Dermatology ◽  
2013 ◽  
Vol 226 (4) ◽  
pp. 329-332 ◽  
Author(s):  
Emiliano Antiga ◽  
Marzia Caproni ◽  
Paolo Fabbri

2019 ◽  
Vol 85 (3) ◽  
pp. 570-579 ◽  
Author(s):  
Bethsabée Garel ◽  
Saskia Ingen‐Housz‐Oro ◽  
Daniele Afriat ◽  
Catherine Prost‐Squarcioni ◽  
Florence Tétart ◽  
...  

2019 ◽  
Vol 12 (12) ◽  
pp. e233281 ◽  
Author(s):  
Htay Phyu ◽  
Takaaki Kobayashi ◽  
Prerna Rastogi ◽  
Christine Cho

Author(s):  
Hiroshi Mitsui ◽  
Keiko Tanaka ◽  
Takashi Okamoto ◽  
Youichi Ogawa ◽  
Shinji Shimada ◽  
...  

2010 ◽  
Vol 37 (3) ◽  
pp. 276-279 ◽  
Author(s):  
Masahiro HAYASHI ◽  
Fumiko MONMA ◽  
Yoshiyuki KATAGIRI ◽  
Masakazu KAWAGUCHI ◽  
Tamio SUZUKI

2010 ◽  
Vol 37 (3) ◽  
pp. 269-271 ◽  
Author(s):  
Kayo JIN ◽  
Hajime NAKANO ◽  
Eijiro AKASAKA ◽  
Daiki ROKUNOHE ◽  
Satoko MINAGAWA ◽  
...  

2015 ◽  
Vol 7 (2) ◽  
pp. 183-186 ◽  
Author(s):  
Eijiro Akasaka ◽  
Sato-Jin Kayo ◽  
Hajime Nakano ◽  
Norito Ishii ◽  
Takashi Hashimoto ◽  
...  

Linear immunoglobulin A (IgA) bullous dermatosis (LABD) is an autoimmune mucocutaneous disease characterized by subepidermal blistering induced by IgA autoantibodies against several autoantigens in the basal membranous zone of the skin and mucosal tissue. Although diaminodiphenyl sulfone (DDS), also known as dapsone, is generally recognized as the first-line therapy for LABD, DDS can induce several severe side effects. We present a Japanese case of LABD with DDS-induced hemolytic anemia and alopecia. In the present case, the DDS-induced hemolytic anemia and hair loss made the DDS monotherapy difficult. When DDS is used in LABD patients with iron deficiency anemia (IDA), hemolytic anemia is concealed by IDA. It is thus necessary to carefully and frequently examine the laboratory data to find the signs of DDS-induced hemolytic anemia. Even though there is no literature on DDS-induced alopecia, alopecia was reported as one of the side effects of DDS in an FDA report, and, in our case, hair loss was improved after reducing its dosage. We have to recognize that alopecia is one of the side effects of DDS and that careful management is needed in order not to overlook the adverse side effects of DDS when treating LABD patients.


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