scholarly journals Effect of purple sweet potato (Ipomoea batatas L) extract on malondialdehyde levels of male white rat (Rattus norvegicus Wistar strain) model of atherosclerosis

2019 ◽  
Author(s):  
Meddy Setiawan ◽  
Fakih Nadhil
Keyword(s):  
Sweet Potato ◽  
Rattus Norvegicus ◽  
Ipomoea Batatas ◽  
Control Treatment ◽  
Control Group ◽  
Experimental Animals ◽  
Wistar Strain ◽  
Potato Extract ◽  
Purple Sweet Potato ◽  
Strain Model

Cardiovascular disease is a disease caused by impaired functions of heart and blood vessel, one of those is coronary heart disease. This study aimed to identify the effect of purple sweet potato (Ipomoea batatas L) extract on MDA (Malondialdehyde) levels of male white rat (Rattus norvegicus Wistar strain) model of atherosclerosis. This research was an experimental study using Post-Test Only Control Group Design method, used 5 groups (positive control group, negative control, treatment 1, treatment 2, and treatment 3), each group contained 5 rats plus 2 reserve rats. ANOVA one way test obtained a significance of 0.00 (p <0.05). The regression test results showed the coefficient of determination R² = 0.71, which means a decrease in serum MDA levels of experimental animals is influenced by the dose of purple sweet potato extract administration as much as 71% while the remaining 29% can be influenced by factors outside the study. It can be concluded that purple sweet potato extract can affect serum MDA levels of experimental animals.

Pengaruh Profilaksis Ekstrak Ubi Jalar Ungu (Ipomoea batatas L.) terhadap Kadar Malondialdehida Hepar Tikus Putih (Rattus norvegicus) Jantan Galur Wistar yang Diinduksi Karagenan

2018 ◽  
Vol 15 (2) ◽  
pp. 146
Author(s):  
BRILIAN DINANTI ◽  
FITRI HANDAJANI
Keyword(s):  
Sweet Potato ◽  
Ipomoea Batatas ◽  
Wistar Rats ◽  
Group Method ◽  
Control Group ◽  
Intraplantar Injection ◽  
Significant Difference ◽  
Male Wistar Rats ◽  
Potato Extract ◽  
Purple Sweet Potato

<p>Liver is an organ with complex metabolism. When the liver is inflamed, cellular immunity will defend against inflammatory agents by stimulating immune cells to produce reactive oxygen species (ROS). Excessive ROS accumulation cause oxydative stress with increased  liver malondialdehyde (MDA) level. Some researches showed that purple sweet potato contain flavonoids (anthocyanins) that functioned as antioxydants. This study aimed to show the prophylactic effect of purple sweet potato extract to the liver MDA level of male Wistar rats induced by carrageenan.</p><p>This study used post-only control group method using 18 male Wistar rats divided into 3 groups: group of rats without treatment, group of rats induced by 0,1 ml of 1% carrageenan by intraplantar injection on day-8, and group of rats given with 872 mg/kgBW of purple sweet potato extract for 7 days and induced by 0,1 ml of 1% carrageenan. In the end of the study, the liver MDA levels were measured by Thio-Barbituric Acid method on each groups.</p><p>The results of One-Way ANOVA test showed there was no significant difference (p = 0,290) between group of rats without treatment (<em>x̅</em>= 207,50) and group of rats induced by carrageenan (<em>x̅</em>=233,17). Then, there is no significant difference (p = 0.978) between group of rats induced by carrageenan and group of rats given with prophylactic purple sweet potato extract and induced by carrageenan (<em>x̅</em>= 232,50).</p><p>The conclusion of this study is giving intraplantar injection of carrageenan can increase liver MDA level insignificantly and giving prophylactic purple sweet potato extract has an effect to decrease the liver MDA level of rats induced by carragenan insignificantly because it contains anthocyanins as antioxidants.</p><p> </p><strong>Keywords: </strong>Liver, <em>Ipomoea batatas</em> L., Malondialdehyde, Anthocyanins

scholarly journals Effect of Purple Sweet Potato Extract (Ipomoea batatas L) on Zebrafish (Danio rerio) By Diet Induced Obesity

2019 ◽  
Vol 6 (2) ◽  
pp. 83-93
Author(s):  
Aswaty Nur ◽  
Yhusi Karina Riskawati ◽  
Edwin Widodo ◽  
Retty Ratnawati ◽  
Amirah Firdausy ◽  
...  
Keyword(s):  
Sweet Potato ◽  
Danio Rerio ◽  
Ipomoea Batatas ◽  
Diet Induced Obesity ◽  
Potato Extract ◽  
Purple Sweet Potato

The Effect of Fermented Purple Sweet Potato (Ipomoea batatas L) Skin in Diets on Feed and Anthocyanin Consumption, Carcass Characteristics, Anthioxidant Profile and Meat Texture of Bali Duck

2016 ◽  
Vol 2 (9) ◽  
pp. 57
Author(s):  
T.G. Belawa Yadnya ◽  
AA. A.S. Trisnadewi ◽  
I Ketut Sukada ◽  
I Gusti Lanang Oka
Keyword(s):  
Superoxide Dismutase ◽  
Sweet Potato ◽  
Ipomoea Batatas ◽  
Control Diet ◽  
Carcass Characteristics ◽  
Carcass Weight ◽  
Control Group ◽  
Antioxidant Profile ◽  
Potato Skin ◽  
Purple Sweet Potato

An experiment was carried out to determine the effect of fermented purple sweet potato (Ipomoea batatas L) skin in diets on feed and anthocyanin consumption, carcass characteristics antioxidant profile and meat texture of Bali duck.. Five  treatment diets were used in a completely randomized design (CRD) consisted of control diet A (diet without containing purple sweet potato skin), diet B containing 10% purple sweet potato skin, diet C containing 10% fermented purple sweet potato skin, diet D containing 20% purple sweet potato skin, diet E containing 20% fermented purple sweet potato skin.Each treatment consisted of four replications and each replicate had five ducks. The variables observed were feed and anthocyanin consumption,slaughter weight, carcass weight, carcass percentage, carcass physical composition,  meat antioxidant profile (capacity antioxidant (CA), malondialdehide (MDA), and superoxide dismutase (SOD). Experiment results showed that diets with fermented or unfermented purple sweet potatoin diets treatments B, C, D, and E increased the anthocyanin  consumption,  slaughter weight, carcass weight, carcass percentage and meat percentage of duck carcass but decreased  their fat and skin. Fermented purple sweet potato (Ipomoea batatas L) skin  in  C and E increased the antioxidant capacity(AC)  and superoxide dismutase (SOD) while  treatment B and  D were not significantly different (P>0.05) to the control group.  Malondialdehide (MDA) of the duck meat in treatment B,C, and D were significantly lower (P<0.05) compared to the control diet. Treatment E significantly  increased the perimesium and endomesium of meat texture , but its experiment was not significantly different to the control group. It was concluded that substitution of fermented purple sweet potato (Ipomoea batatas L) skin in diets could improve of feed and anthocyanin, carcass characteristics, antioxidant profile, and meat texture of bali duck.

scholarly journals IDENTIFIKASI UJI FORMALIN PADA MIE BASAH MENGUNAKAN EKSTRAK UBI JALAR UNGU (Ipomoea batatas L.) DI PASAR TRADISIONAL DESA NIRU MUARA ENIM

2021 ◽  
Vol 8 (2) ◽  
pp. 14-20
Author(s):  
Rahmi Garmini
Keyword(s):  
Experimental Design ◽  
Sweet Potato ◽  
Human Body ◽  
Ipomoea Batatas ◽  
Chemical Additives ◽  
Potato Extract ◽  
Purple Sweet Potato ◽  
Food Needs

The use of chemical additives, especially formaldehyde in food, needs to be watched out for together, both by producers and consumers. The use of formaldehyde in food is not allowed because it can cause poisoning in the human body. The purpose of this study was to describe the use of anthocyanin extract of purple sweet potato (Ipomoea batatas L.) as a natural indicator for formalin detection. The method used is experimental design. The results of this study can be seen that purple sweet potato contains anthocyanins which can be an indicator material for formalin which is acidic, this can be seen from the change in the color of the anthocyanin extract which changes when reacted with formalin, and seen from the purple sweet potato extract it turns reddish blue.

scholarly journals UMBI UBI JALAR UNGU BALI (Ipomoea batatas) DI TRANSAMINASE SERUM, MALONDIALDEHIDE HEPAR DAN ALKOHOL KRONIS

2018 ◽  
Vol 17 (3) ◽  
pp. 151
Author(s):  
I Wayan Putu Sutirta-Yasa ◽  
I Made Jawi ◽  
Ida Bagus Ngurah ◽  
Anak Agung Ngurah Subawa
Keyword(s):  
Sweet Potato ◽  
Liver Tissue ◽  
Ipomoea Batatas ◽  
Ethanol Extract ◽  
Antioxidant Effect ◽  
Control Group ◽  
Chronic Alcoholic ◽  
Purple Sweet Potato ◽  
Group Post ◽  
Alcoholic Intake

Oxidative stress as a consequence of chronic alcoholic intake causes lesions of liver tissue. The objective of this study was to identifythe antioxidant effect of ethanol extract derived from Balinese purple sweet potato on the liver tissue in mice after chronic consumptionof alcohol. Subjects of this study were 32 adults male Swiss mice (12–14 weeks) divided into 4 groups with control group post-testonly design. Post-treatment of blood and liver samples were collected from each group of 8 mice. The MDA liver was quantified withthiobarbituric acid reactive substances (TBARS) method. Samples were collected from control group of 8 mice without sweet potatoextract and alcohol, 8 mice with 1 mg extract of Balinese purple sweet potato, 8 mice with 0.8 gram alcohol, and 8 mice with combineof alcohol and extract of Balinese purple sweet potato, each treatment was carried out every day for 4 weeks. The results showed asignificant increase of serum SGOT, SGPT and liver MDA level, after chronic consumption of alcohol (p = 0.00). The decrease of serumSGOT, SGPT and liver level MDA was significant in the group with extract of Balinese purple sweet potato (p = 0.00). The researchersconcluded that the extract of Balinese purple sweet potato had an antioxidant effect in mice which consumed alcohol chronically. Basedon this study it is concluded that extract of Balinese purple sweet potato has a protective effect on the liver cell in mice which consumedalcohol chronically.

scholarly journals PURPLE SWEET POTATO (Ipomoea batatas L.) PEELS EXTRACT AS AN ALTERNATIVE DYE FOR BACTERIA GRAM STAINING

2020 ◽  
Vol 2 (2) ◽  
pp. 76-84
Author(s):  
Nastasya Nunki ◽  
Diah Titik Mutiarawati ◽  
Endah Prayekti
Keyword(s):  
Sweet Potato ◽  
Ipomoea Batatas ◽  
Gentian Violet ◽  
Glass Slide ◽  
Control Group ◽  
Anthocyanin Pigment ◽  
Extract Concentration ◽  
Gram Staining ◽  
Potato Peels ◽  
Purple Sweet Potato

Crystal violet and Safranin are dyes in Gram staining, which are carcinogenic. Alternative safe materials are needed to minimize the use of carcinogenic properties. Purple sweet potato (Ipomoea batatas L.) peels were the candidate of the alternative dye source because of its high anthocyanin pigment. The purpose of this study was to determine purple sweet potato (Ipomoea batatas L.) peels extract as an alternative to Gentian violet in Gram staining of bacteria. Extracts obtained from purple sweet potato peels studied with varying concentrations of 50%, 60%, and 75% for 1, 3, and 5 min as a substitute for Gentian violet on Bacillus sp. The parameters observed from this study based on visual field clarity, glass slide cleanliness, contrast, bacterial shape, bacterial colour. Each extract concentration compared with a control group using Gentian violet. The results showed that optimum staining in 50% concentration for 5 min, 60% concentration for 5 min, 75% concentration for 3 min, and 5 min respectively. The present study exhibited the potency of Ipomoea batatas L. peels extract as an alternative staining agent.

scholarly journals Neuroprotective Effects of Purple Sweet Potato Balinese Cultivar in Wistar Rats With Ischemic Stroke

2018 ◽  
Vol 6 (11) ◽  
pp. 1959-1964 ◽  
Author(s):  
I Made Oka Adnyana ◽  
AA Raka Sudewi ◽  
DPG Purwa Samatra ◽  
DN Suprapta
Keyword(s):  
Ischemic Stroke ◽  
Cytochrome C ◽  
Sweet Potato ◽  
Ipomoea Batatas ◽  
Caspase 3 ◽  
Neuroprotective Effect ◽  
Control Group ◽  
Neuroprotective Effects ◽  
Apoptosis Rate ◽  
Purple Sweet Potato

BACKGROUND: Purple sweet potato (Ipomoea Batatas L.) is one of the sources for anthocyanin, which promotes the health through antioxidant, anti-inflammatory, anti-cancer, neuroprotection, and anti-apoptosis activities. Oxidative stress has been shown to be the cause of apoptosis in ischemic stroke. AIM: The objective of this research was to delineate the pleiotropic effects of anthocyanin for neuroprotection during an acute stroke event. METHODS: Anthocyanin was extracted from Balinese cultivar of purple sweet potato and subsequently administered to rat models of induced ischemic stroke (labelled as treatment group), as well as a placebo (labelled as a control group). Several parameters were in turn evaluated, i.e. the activities of anti-apoptotic (Bcl-2) as well as pro-apoptotic (cytochrome c, caspase-3) molecules, and apoptosis rate. Bcl-2 levels were determined using the histochemical method, cytochrome c and caspase-3 via ELISA method, while apoptosis rate was measured by TdT-medicated Dutp-Nick End Labeling (TUNEL) assay. RESULTS: Bcl-2 expression demonstrated significantly higher Bcl-2 expression in the treatment compared with control group (median 31.2 vs. 1.1; p = 0.001). Accordingly, pro-apoptotic cytochrome c and caspase-3 levels were also found significantly lower in the treatment as opposed to control group (mean 4.17 vs. 8.06; p = 0.001; mean 3.81 vs. 8.02; p = 0.001). Ultimately, apoptosis rate was found markedly lower among treatment than control groups (mean 3.81 vs. control 21.97; p = 0.003). CONCLUSION: The results of this study indicated a significant neuroprotective effect of anthocyanin derived from Balinese cultivar of PSP. Anthocyanin was able to increase and reduce anti-apoptotic and pro-apoptotic protein levels, respectively, resulting in lesser cellular apoptotic rate when compared with placebo. The potential mechanism was thought mainly due to its anti-oxidant properties.

Effects of Purple Sweet Potato Extract Addition in Ascorbic Acid Inhibitor to Corrosion Rate of API 5L Steel in 3.5%NaCl Environment

2014 ◽  
Vol 709 ◽  
pp. 384-389 ◽  
Author(s):  
Ayende ◽  
Andi Rustandi ◽  
Johny Wahyuadi Soedarsono ◽  
Dedi Priadi ◽  
Sulistijono ◽  
...  
Keyword(s):  
Ascorbic Acid ◽  
Corrosion Rate ◽  
Corrosion Inhibitor ◽  
Sweet Potato ◽  
Ipomoea Batatas ◽  
Enzyme Reaction ◽  
Liquid Form ◽  
Acid Inhibitor ◽  
Potato Extract ◽  
Purple Sweet Potato

Using vitamin C or ascorbic acid as corrosion inhibitor has several weakness. In its liquid form ascorbic acid is easily oxidized and its anti oxidant properties unstable due to heat, light, oxidizer, dissolved oxygen and heavy metals. Purple sweet potato (ipomoea batatas L) with its high anthocyanin is one of alternative for green corrosion inhibitor. Extract of purple sweet potato has the ability to hold the enzyme reaction and oxidation proses of ascorbic acid. Purple sweet potato extract mixed with ascorbid acid is used as inhibitor of API 5L steel in 3.5%NaCl. This compound is classifid as mixed type inhibitor. The adding of purple sweet potato extract will assist ascorbic acid to maintance its inhibition efficiency and increases surface layer corrosion resistant of steel. Polarization methods and electrocehmical impedance spectroscopy (EIS) are used to investigate corrosion rate and mechanism of the steel. Appliaction of 4 ml purple sweet potato mixed with 10-4M ascorbic acid inhibitor increases inhibition ability of API 5L steel from 23.5 to 57.52%. Purple sweet potato extract moves polarization curve to lower potential (below 82 mVolt) with tends to be more negative.

scholarly journals Pengaruh Pemberian Ekstrak Etanol Daun Ubi Jalar Ungu (Ipomoea Batatas (L.) Lam) terhadap Kadar Kolesterol Ldl Tikus Hiperkolesterolemia

2019 ◽  
Vol 2 (2) ◽  
pp. 184
Author(s):  
Siti Fatimah ◽  
Yuliana Prasetyaningsih
Keyword(s):  
Treatment Group ◽  
Cholesterol Level ◽  
Sweet Potato ◽  
Ipomoea Batatas ◽  
Ldl Cholesterol ◽  
Ethanol Extract ◽  
Control Group ◽  
Cholesterol Levels ◽  
Purple Sweet Potato ◽  
Sweet Potato Leaves

Hypercholesterolemia is still a health problem today because it is associated with the onset of cardiovascular disorders with various complications. High cholesterol levels carried by the blood will accumulate in the arteries that cause atherosclerosis. Blood clots and blockage of blood vessels can result in the stroke or heart attack. Flavonoids that are found in purple sweet potato leaves are quercetin. Quercetin has antioxidant effects that can improve blood vessel endothelial function, reduce LDL sensitivity to free radical effects, and reduce blood lipid levels. This study aims to determine the effect of ethanol extract of purple sweet potato leaves on LDL cholesterol level of hypercholesterolemia rat. The experiment was conducted experimentally using 2 groups of Wistar rats (each group consisting of 5 tails), namely the control group and the treatment group. Induction of hypercholesterolemia was performed with a high-fat diet for 7 days. The purple sweet potato ethanol extract was administered sonde in the treatment group with a quercetin dose of 2 mg /kg/day for 14 days and the measurement of LDL cholesterol was performed on days 10 and 24 by the CHOD-PAP method. Data were analyzed by Paired t-test. The results showed that LDL cholesterol level in the treatment group showed that 5 mice had decreased, the mean decrease of 32,49 mg/dl while control group 3 decreasing, mean 0,65 mg /dl. There was a significant difference (p <0.05) on changes in LDL cholesterol levels in the treatment group. Provision of purple sweet potato ethanol extract with quercetin dose of 2 mg/kg for 14 days can decrease LDL cholesterol level of hypercholesterolemia rat. From the results of this study is expected to optimize the utilization of purple sweet potato leaves (Ipomoea batatas (L.) Lam) as a drug for lowering LDL cholesterol.

scholarly journals FORMULASI SEDIAAN PERONA PIPI EKSTRAK ETANOL UBI JALAR UNGU (Ipomoea batatas L.) DALAM BENTUK STICK

PHARMACON ◽  
2021 ◽  
Vol 10 (1) ◽  
pp. 743
Author(s):  
Novia Hanna Purnomo ◽  
Hosea Jaya Edy ◽  
Jainer Pasca Siampa
Keyword(s):  
Physical Properties ◽  
Sweet Potato ◽  
Ipomoea Batatas ◽  
Ph Value ◽  
Skin Irritation ◽  
Preference Test ◽  
Natural Dye ◽  
Determining Factors ◽  
Potato Extract ◽  
Purple Sweet Potato

ABSTRACTColor is one of the determining factors in quality in cosmetics. Usage of synthjetic dye in blush on could cause irritation on facial skin, irritation on respiratory tract, and damage to the liver. The aim of this study was to formulate and to evaluate the physical characterization of the blush on preparation by using natural dye from the purple sweet potato extract (Ipomoea batatas L.) with the variation concentration on 20%, 25%, and 30%. Formulation of stick blush on used fusion method. The extract is obtained by means of maceration using ethanol solvent 96%. Organoleptics, color homogeneity, pH, stability toward light, polish test and preference test were included in the evaluation of the physical properties of the preparation. The result of the physical properties test showed the preparation’s color ranged from pale purple to dark pink, a distinctive scent of oleum rose perfume, soft texture, all preparation had homogenous arrangement, pH value of the preparation  ranged from 6.00-6.61, the best polish were on concentration 25% and 30% this is characterized by a one-time polishing of the ready has given a clear color when polished on the skin of the back of the hand, color observation at all preparation did not had any changes in 14 days, and the preferred preparation by the panelists were the preparation with pigment concentration of 20%, 25% and 30%. It can be concluded that the combination of the purple sweet potato extract (Ipomoea batatas L.) can be used as a natural dye in blush on preparation. Keywords: Ipomoea batatas L., Blush on, Formulation  ABSTRAK Warna adalah salah satu faktor penentu mutu kosmetika. Penggunaan pewarna sintesis pada perona pipi dapat menyebabkan iritasi pada kulit wajah, iritasi pada saluran pernapasan, dan kerusakan pada hati. Tujuan Penelitian ini untuk memformulasi serta mengetahui evaluasi fisik sediaan perona pipi dengan memanfaatkan pewarna alami dari ekstrak ubi jalar ungu (Ipomoea batatas L.) dengan konsentrasi 20%, 25% dan 30%. Pembuatan sediaan perona pipi menggunakan metode peleburan. Evaluasi fisik sediaan meliputi organoleptik, homogenitas warna, pH, stabilitas terhadap cahaya, uji poles dan uji kesukaan. Hasil pengujian sifat fisik menunjukkan bahwa sediaan yang dihasilkan memberikan warna ungu pucat hingga merah muda tua, bau khas parfum oleum rose, teksturnya lembut, semua sediaan memiliki susunan yang homogen, nilai pH sediaan 6,00-6,61, polesan terbaik pada konsentrasi 25% dan 30% hal ini ditandai dengan satu kali pemolesan sediaan telah memberikan warna yang jelas saat dipoleskan pada kulit punggung tangan , selama 14 hari pengamatan warna pada semua sediaan tidak mengalami perubahan terhadap cahaya, dan sediaan yang disukai oleh panelis adalah sediaan dengan konsentrasi zat warna 20%, 25% dan 30%. Dengan demikian dapat disimpulkan bahwa ekstrak etanol Ubi Jalar Ungu (Ipomoea batatas L.) dapat digunakan sebagai pewarna alami dalam sediaan perona pipi. Kata kunci: Ipomoea batatas L., Perona pipi, Formulasi

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