scholarly journals Activation of Plasmacytoid Dendritic Cells in Colon-Draining Lymph Nodes duringCitrobacter rodentiumInfection Involves Pathogen-Sensing and Inflammatory Pathways Distinct from Conventional Dendritic Cells

2016 ◽  
Vol 196 (11) ◽  
pp. 4750-4759 ◽  
Author(s):  
Raine Toivonen ◽  
Lingjia Kong ◽  
Omid Rasool ◽  
Riikka J. Lund ◽  
Riitta Lahesmaa ◽  
...  
Keyword(s):  
Dendritic Cells ◽  
Lymph Nodes ◽  
Plasmacytoid Dendritic Cells ◽  
Inflammatory Pathways ◽  
Draining Lymph Nodes

Plasmacytoid Dendritic Cells from Human Lung Cancer Draining Lymph Nodes Induce Tc1 Responses

2007 ◽  
Vol 36 (3) ◽  
pp. 360-367 ◽  
Author(s):  
Alexander Faith ◽  
Emma Peek ◽  
Joanne McDonald ◽  
Zoe Urry ◽  
David F. Richards ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Dendritic Cells ◽  
Lymph Nodes ◽  
Human Lung ◽  
Plasmacytoid Dendritic Cells ◽  
Human Lung Cancer ◽  
Draining Lymph Nodes

scholarly journals Plasmacytoid dendritic cells from mouse tumor-draining lymph nodes directly activate mature Tregs via indoleamine 2,3-dioxygenase

2007 ◽  
Vol 117 (9) ◽  
pp. 2570-2582 ◽  
Author(s):  
Madhav D. Sharma ◽  
Babak Baban ◽  
Phillip Chandler ◽  
De-Yan Hou ◽  
Nagendra Singh ◽  
...  
Keyword(s):  
Dendritic Cells ◽  
Lymph Nodes ◽  
Plasmacytoid Dendritic Cells ◽  
Mouse Tumor ◽  
Indoleamine 2,3 Dioxygenase ◽  
Draining Lymph Nodes

scholarly journals Dendritic Cell Populations in Leishmania major-Infected Skin and Draining Lymph Nodes

2004 ◽  
Vol 72 (4) ◽  
pp. 1991-2001 ◽  
Author(s):  
Tracey Baldwin ◽  
Sandrine Henri ◽  
Joan Curtis ◽  
Meredith O'Keeffe ◽  
David Vremec ◽  
...  
Keyword(s):  
Dendritic Cells ◽  
Dendritic Cell ◽  
Lymph Nodes ◽  
Leishmania Major ◽  
Mouse Skin ◽  
Parasite Load ◽  
Plasmacytoid Dendritic Cells ◽  
Cell Populations ◽  
Infection Model ◽  
Draining Lymph Nodes

ABSTRACT Using a metacyclic promastigote ear infection model of cutaneous leishmaniasis, we examined the phenotype, parasite load, and cytokine production of dendritic cells in the skin and draining lymph nodes of resistant C57BL/6J and susceptible BALB/c mice. Five dendritic cell populations were isolated from the skin and lymph nodes, and the main difference between the groups of mice was an increased number of plasmacytoid dendritic cells in the lymph nodes of the susceptible mice. Although similar cell types were present in the skin emigrants of both strains, there was a 10-fold larger number of cells in BALB/c mouse skin early in infection than in C57BL/6J mouse skin. None of the dendritic cells in the lymph nodes harbored parasites until 3 weeks after infection, with the Langerhans cells having the largest load and the plasmacytoid dendritic cells having the smallest load but the longest lasting infection. Although parasites could be detected in the lymph nodes a few hours after infection, none of the skin emigrants harbored parasites, indicating that they are not the vehicle that ferries the parasites from the skin to the lymph nodes. The presence of larger numbers of plasmacytoid cells in infected BALB/c mice, the more protracted infection of these cells, and their production of alpha interferon point to a complex and important role for the plasmacytoid cells in leishmaniasis.

scholarly journals Expression of indoleamine 2,3-dioxygenase by plasmacytoid dendritic cells in tumor-draining lymph nodes

2004 ◽  
Vol 114 (2) ◽  
pp. 280-290 ◽  
Author(s):  
David H. Munn ◽  
Madhav D. Sharma ◽  
Deyan Hou ◽  
Babak Baban ◽  
Jeffrey R. Lee ◽  
...  
Keyword(s):  
Dendritic Cells ◽  
Lymph Nodes ◽  
Plasmacytoid Dendritic Cells ◽  
Indoleamine 2,3 Dioxygenase ◽  
Draining Lymph Nodes

scholarly journals Expression of indoleamine 2,3-dioxygenase by plasmacytoid dendritic cells in tumor-draining lymph nodes

2004 ◽  
Vol 114 (4) ◽  
pp. 599-599 ◽  
Author(s):  
David H. Munn ◽  
Madhav D. Sharma ◽  
Deyan Hou ◽  
Babak Baban ◽  
Jeffrey R. Lee ◽  
...  
Keyword(s):  
Dendritic Cells ◽  
Lymph Nodes ◽  
Plasmacytoid Dendritic Cells ◽  
Indoleamine 2,3 Dioxygenase ◽  
Draining Lymph Nodes
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