Artificially Disseminated Virus as a Factor Controlling the European Spruce Sawfly, Diprion hercyniae (Htg.) in the Absence of Introduced Parasites

1961 ◽  
Vol 93 (3) ◽  
pp. 228-238 ◽  
Author(s):  
F. T. Bird ◽  
J. M. Burk
Keyword(s):  
Virus Disease ◽  
Population Trends ◽  
Long Term Effects ◽  
Eastern Canada ◽  
Forest Insect ◽  
Insect Survey ◽  
Forest Biology ◽  
Biology Laboratory ◽  
Disease Free

An outbreak of the European spruce sawfly, Diprion hercyniae (Htg.), occurring in Eastern Canada between 1930 and 1942, was controlled by a virus disease (Balch and Bird, 1944). The sawfly has been kept at a low level by the disease and by parasitic insects introduced from Europe (Bird and Elgee, 1957).An infestation of the sawfly was discovered in 1947 near Sault Ste. Marie, Ontario, by the Forest Insect Survey Section of the Forest Biology Laboratory at Sault Ste. Marie. This infestation was about 100 miles beyond the previously known western distribution of the insect. Intensive larval sampling in 1949 showed that it was free from virus and practically free from introduced parasites. Thus, an excellent opportunity was provided to introduce the virus into a disease-free population, to study its establishment and spread, and to compare the long term effects of virus alone on population trends with the effects that virus plus introduced parasites were shown to have on population trends in New Brunswick (Bird and Elgee, 1957). The virus was introduced into the infestation in 1950 and studies were carried out each year from 1950 to 1959.

Estimation of Parasitism of Larch Sawfly Cocoons by Bessa harveyi Tnsd. in Survey Collections

1959 ◽  
Vol 91 (8) ◽  
pp. 496-500 ◽  
Author(s):  
W. G. H. Ives ◽  
R. M. Prentice
Keyword(s):  
Forest Insect ◽  
Small Areas ◽  
Pristiphora Erichsonii ◽  
Larch Sawfly ◽  
Insect Survey ◽  
Forest Biology ◽  
Biology Laboratory ◽  
Total Parasitism

The Forest Insect Survey at the Forest Biology Laboratory, Winnipeg, has been compiling records for a number of years on the percentage of cocoons of the larch sawfly, Pristiphora erichsonii (Htg.), parasitized by the tachinid Bessa harveyi Tnsd. Sawfly cocoons were collected each fall from the soil in infested stands, and those containing living larvae were dissected to determine the percentage of parasitism by B. harveyi. These estimates have been used to provide an index of parasitism (Lejeune and Hildahl, 1954), but are of limited value for a number of reasons: (1) estimates can be expressed only as percentage of sound cocoons parasitized; (2) total parasitism cannot be estimated because a portion of the parasites emerge from the cocoons before collection; and (3) estimates of parasitism may not be representative of the stand because there is a tendency to collect cocoons where they are easiest to find; hence all the cocoons in a collection may be from one or two small areas. If the proportion of cocoons containing B. harveyi varies within a stand such collections may give unreliable estimates of parasitism.

Storage of Preserved Insect Specimens

1958 ◽  
Vol 90 (8) ◽  
pp. 461-463
Author(s):  
David Evans
Keyword(s):  
Hypodermic Needle ◽  
Air Bubbles ◽  
Forest Insect ◽  
The Past ◽  
Insect Survey ◽  
Forest Biology ◽  
Biology Laboratory ◽  
Small Shell ◽  
Outside Diameter

Several methods of storing insect specimens in liquid preservatives have been used at the Forest Biology Laboratory at Victoria, all of them unsatisfactory to a varying degree. The method described herein was devised by the author and has proved successful during the past year.Homeopathic vials approximately 62 mm. overall outside length × 15 mm. greatest outside diameter × 11 mm. inside neck measurement, with 000 rubber stoppers, are the most suitable size for insect specimens. The different stages of nearly any of the species of insects encountered by the Forest Insect Survey can be easily accommodated in a single vial of this size. Small shell vials may be used for double mounts when tiny insects are involved which might otherwise be lost in the larger vials. For material too large for the 11 mm. neck of the homeopathic vial, shell vials 65 mm. × 15 mm. can be used with serum sleeve-type stoppers. All but mass collections and a few of the larvae can be preserved in these sizes. Both types of rubber stoppers are satisfactory, although the sleeve type requires more effort to put on and seal, and also conceals the top of the vial. Air bubbles can be removed from the latter by inserting a hypodermic needle through the top of the stopper.

Notes on Matsucoccus macrocicatrices Richards (Homoptera: Margarodidae) and its Association with Septobasidium pinicola Snell in Eastern Canada

1960 ◽  
Vol 92 (9) ◽  
pp. 662-667 ◽  
Author(s):  
W. Y. Watson ◽  
G. R. Underwood ◽  
J. Reid
Keyword(s):  
Scale Insects ◽  
Herbarium Specimens ◽  
White Pine ◽  
Maritime Provinces ◽  
Eastern Canada ◽  
Pathology Laboratory ◽  
Pinus Rigida ◽  
Pine Trees ◽  
Forest Biology ◽  
Biology Laboratory

Three known species of scale insects belonging to the genus Matsucoccus occur on pine trees in northeastern North America: M. gallicolis Morr., on pitch pine, Pinus rigida Mill., and scrub pine, Pinus virginiana Mill. (Parr, 1939); M. resinosae Bean and Godwin on red pine, P. resinosa Ait. (Bean and Godwin, 1955); and M. macrocicatrices Richards on eastern white pine, P. strobus L. (Richards, 1960). This last species. in contrast with the others, is closely associated with the fungus Septobasidium pinicola Snell. From 1957 to 1959 personnel of the Forest Insect Laboratory, Sault Ste. Marie, and the Forest Biology Laboratory, Fredericton, collected some 500 specimens from 21 areas in Ontario and the Maritime Provinces. These collections, augmented by herbarium specimens provided by the Forest Pathology Laboratory, Maple, from five other areas in Ontario, not only the insect specimens necessary for the dercription of the species, but information on its biology and distribution.

scholarly journals Nonclonal Chromosome Aberrations and Genome Chaos in Somatic and Germ Cells from Patients and Survivors of Hodgkin Lymphoma

Genes ◽  
2019 ◽  
Vol 10 (1) ◽  
pp. 37 ◽  
Author(s):  
Sara Frias ◽  
Sandra Ramos ◽  
Consuelo Salas ◽  
Bertha Molina ◽  
Silvia Sánchez ◽  
...  
Keyword(s):  
Hodgkin Lymphoma ◽  
Chromosomal Aberrations ◽  
Chromosomal Instability ◽  
Chromosomal Abnormalities ◽  
Disease Free Survival ◽  
Specific Cell ◽  
Long Term Effects ◽  
Free Survival ◽  
Disease Free

Anticancer regimens for Hodgkin lymphoma (HL) patients include highly genotoxic drugs that have been very successful in killing tumor cells and providing a 90% disease-free survival at five years. However, some of these treatments do not have a specific cell target, damaging both cancerous and normal cells. Thus, HL survivors have a high risk of developing new primary cancers, both hematologic and solid tumors, which have been related to treatment. Several studies have shown that after treatment, HL patients and survivors present persistent chromosomal instability, including nonclonal chromosomal aberrations. The frequency and type of chromosomal abnormalities appear to depend on the type of therapy and the cell type examined. For example, MOPP chemotherapy affects hematopoietic and germ stem cells leading to long-term genotoxic effects and azoospermia, while ABVD chemotherapy affects transiently sperm cells, with most of the patients showing recovery of spermatogenesis. Both regimens have long-term effects in somatic cells, presenting nonclonal chromosomal aberrations and genomic chaos in a fraction of noncancerous cells. This is a source of karyotypic heterogeneity that could eventually generate a more stable population acquiring clonal chromosomal aberrations and leading towards the development of a new cancer.

Two New Species of the Genus Hyperaspis (Coleoptera: Coccinellidae)

1960 ◽  
Vol 92 (3) ◽  
pp. 230-234
Author(s):  
W. Y. Watson
Keyword(s):  
New Species ◽  
North America ◽  
Scale Insects ◽  
Eastern North America ◽  
Forest Insect ◽  
Two New Species ◽  
Forest Biology ◽  
Species Descriptions ◽  
Biology Laboratory

Among the more important predacious coccinellids in eastern North America is Hyperaspis binotata auct., which has been considered a general feeder on Toumeyella numismaticum (P. & M.), Pulvinaria spp., and other scale insects. A review of the specimens identified as H. binotata in the collections of the Forest Insect Laboratory, Sault Ste. Marie, has revealed, not only H. binotata (Say), but two apparently new species, descriptions of which are given in this paper. In addition to the material at Sault Ste. Marie, specimens were obtained from the Canadian National Collection and the Forest Biology Laboratory, Winnipeg, Manitoba.

scholarly journals Impact of COVID-19 on the Endocrine System – a mini-review

Endocrinology ◽  
2021 ◽  
Author(s):  
Sophie A Clarke ◽  
Ali Abbara ◽  
Waljit S Dhillo
Keyword(s):  
Virus Disease ◽  
Case Reports ◽  
Endocrine System ◽  
Endocrine Glands ◽  
Long Term Effects ◽  
Mortality And Morbidity ◽  
Angiotensin Converting Enzyme 2 ◽  
System A ◽  
Transmembrane Serine Protease

Abstract The Corona Virus Disease 2019 (COVID-19) pandemic continues to exert a significant impact on global healthcare systems, causing devastating mortality and morbidity. As time passes and our understanding of this novel respiratory virus deepens, it is increasingly clear that its effects extend beyond that of the respiratory system. The coronavirus responsible for COVID-19, SARS-CoV-2, obtains cellular access through the angiotensin converting enzyme 2 (ACE2) receptor in a process requiring the transmembrane serine protease 2 (TMPRSS2) protein. Both ACE2 and TMPRSS2 are widely expressed in many endocrine glands. This, along with several case reports of thyroid and pituitary disruption in patients with COVID-19, has resulted in significant interest in its impact on the endocrine system. Indeed, as mortality is abated by the increasing availability of effective vaccines, there is increasing focus on the long-term effects on health in COVID-19 survivors. This review summarises data investigating the effects of COVID-19 on each of the endocrine axes to guide appropriate investigations and optimal management.

Ovarian Dysfunction in Fetally Irradiated Beagles

1977 ◽  
Vol 35 ◽  
pp. 658-659
Author(s):  
T. M. Seed ◽  
M. H. Sanderson ◽  
D. L. Gutzeit ◽  
T. E. Fritz ◽  
D. V. Tolle ◽  
...  
Keyword(s):  
Gamma Rays ◽  
Low Dose ◽  
Long Term Effects ◽  
Ovarian Dysfunction ◽  
Dose Rates ◽  
Highly Sensitive ◽  
Microscopic Evaluation ◽  
Ovarian Pathology ◽  
Normal Offspring

The developing mammalian fetus is thought to be highly sensitive to ionizing radiation. However, dose, dose-rate relationships are not well established, especially the long term effects of protracted, low-dose exposure. A previous report (1) has indicated that bred beagle bitches exposed to daily doses of 5 to 35 R 60Co gamma rays throughout gestation can produce viable, seemingly normal offspring. Puppies irradiated in utero are distinguishable from controls only by their smaller size, dental abnormalities, and, in adulthood, by their inability to bear young.We report here our preliminary microscopic evaluation of ovarian pathology in young pups continuously irradiated throughout gestation at daily (22 h/day) dose rates of either 0.4, 1.0, 2.5, or 5.0 R/day of gamma rays from an attenuated 60Co source. Pups from non-irradiated bitches served as controls. Experimental animals were evaluated clinically and hematologically (control + 5.0 R/day pups) at regular intervals.

Ultrastructural investigations of MDL 19,660-induced effects on the canine platelet and megakaryocyte

1990 ◽  
Vol 48 (3) ◽  
pp. 374-375
Author(s):  
D.E. Loudy ◽  
J. Sprinkle-Cavallo ◽  
J.T. Yarrington ◽  
F.Y. Thompson ◽  
J.P. Gibson
Keyword(s):  
Antidepressant Drug ◽  
Beagle Dogs ◽  
Long Term Effects ◽  
Short Term ◽  
Platelet Counts ◽  
Toxicological Studies ◽  
Induced Aggregation ◽  
Internal Architecture

Previous short term toxicological studies of one to two weeks duration have demonstrated that MDL 19,660 (5-(4-chlorophenyl)-2,4-dihydro-2,4-dimethyl-3Hl, 2,4-triazole-3-thione), an antidepressant drug, causes a dose-related thrombocytopenia in dogs. Platelet counts started to decline after two days of dosing with 30 mg/kg/day and continued to decrease to their lowest levels by 5-7 days. The loss in platelets was primarily of the small discoid subpopulation. In vitro studies have also indicated that MDL 19,660: does not spontaneously aggregate canine platelets and has moderate antiaggregating properties by inhibiting ADP-induced aggregation. The objectives of the present investigation of MDL 19,660 were to evaluate ultrastructurally long term effects on platelet internal architecture and changes in subpopulations of platelets and megakaryocytes.Nine male and nine female beagle dogs were divided equally into three groups and were administered orally 0, 15, or 30 mg/kg/day of MDL 19,660 for three months. Compared to a control platelet range of 353,000- 452,000/μl, a doserelated thrombocytopenia reached a maximum severity of an average of 135,000/μl for the 15 mg/kg/day dogs after two weeks and 81,000/μl for the 30 mg/kg/day dogs after one week.

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