scholarly journals Casein phosphopeptide-amorphous calcium phosphate and glass ionomer show distinct effects in the remineralization of proximal artificial caries lesion in situ

2013 ◽  
Vol 32 (4) ◽  
pp. 648-653 ◽  
Author(s):  
Rathapong THEPYOU ◽  
Wanvipa CHANMITKUL ◽  
Ornnicha THANATVARAKORN ◽  
Hidenori HAMBA ◽  
Wanwalai CHOB-ISARA ◽  
...  
Keyword(s):  
Calcium Phosphate ◽  
Amorphous Calcium Phosphate ◽  
Glass Ionomer ◽  
Caries Lesion ◽  
Casein Phosphopeptide

Fluoride and Casein Phosphopeptide-Amorphous Calcium Phosphate

2008 ◽  
Vol 87 (4) ◽  
pp. 344-348 ◽  
Author(s):  
E.C. Reynolds ◽  
F. Cai ◽  
N.J. Cochrane ◽  
P. Shen ◽  
G.D. Walker ◽  
...  
Keyword(s):  
Calcium Phosphate ◽  
Amorphous Calcium Phosphate ◽  
Double Blind ◽  
Water Slurry ◽  
Supragingival Plaque ◽  
Casein Phosphopeptide

Casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) slows the progression of caries and remineralizes enamel subsurface lesions. The aim of this study was to determine the ability of CPP-ACP to increase the incorporation of fluoride into plaque and to promote enamel remineralization in situ. Randomized, double-blind, cross-over studies involved mouthrinses and dentifrices containing CPP-ACP and fluoride. The mouthrinses were used for 60 sec, three times/day for 5 days, and supragingival plaque was collected and analyzed for F. The dentifrices were rinsed as a water slurry for 60 sec four times/day for 14 days in an in situ model. The addition of 2% CPP-ACP to the 450-ppm-F mouthrinse significantly increased the incorporation of fluoride into plaque. The dentifrice containing 2% CPP-ACP produced a level of remineralization similar to that achieved with a dentifrice containing 2800 ppm F. The dentifrice containing 2% CPP-ACP plus 1100 ppm F was superior to all other formulations.

Incorporation of Casein Phosphopeptide-Amorphous Calcium Phosphate into a Glass-ionomer Cement

2003 ◽  
Vol 82 (11) ◽  
pp. 914-918 ◽  
Author(s):  
S.A. Mazzaoui ◽  
M.F. Burrow ◽  
M.J. Tyas ◽  
S.G. Dashper ◽  
D. Eakins ◽  
...  
Keyword(s):  
Calcium Phosphate ◽  
Amorphous Calcium Phosphate ◽  
Glass Ionomer Cement ◽  
Glass Ionomer ◽  
Casein Phosphopeptide ◽  
Ionomer Cement

Casein Phosphopeptide-Amorphous Calcium Phosphate Incorporated into Sugar Confections Inhibits the Progression of Enamel Subsurface Lesions in situ

2010 ◽  
Vol 44 (1) ◽  
pp. 33-40 ◽  
Author(s):  
G.D. Walker ◽  
F. Cai ◽  
P. Shen ◽  
G.G. Adams ◽  
C. Reynolds ◽  
...  
Keyword(s):  
Calcium Phosphate ◽  
Amorphous Calcium Phosphate ◽  
Casein Phosphopeptide

scholarly journals Efficacy of casein derivate CPP-ACP1

2014 ◽  
Vol 62 (3) ◽  
pp. 243-252
Author(s):  
Renata Faria PEREIRA ◽  
Soraya Coelho LEAL
Keyword(s):  
Calcium Phosphate ◽  
Randomized Controlled Trials ◽  
Systematic Reviews ◽  
Amorphous Calcium Phosphate ◽  
Controlled Trials ◽  
Randomized Controlled ◽  
Pubmed Database ◽  
Casein Phosphopeptide

OBJECTIVE: A literature review of systematic reviews and in situ and in vivo randomized controlled trials was conducted in order to assess the role of casein phosphopeptide - amorphous calcium phosphate in providing caries-preventive effect superior to any intervention or placebo. METHODS: Initially, Pubmed database was searched for systematic reviews. Two systematic reviews were identified, which concluded that the quantity and quality of randomized controlled trials were insufficient to recommend the clinical use of the product. After this, Pubmed database was searched for in situ and in vivo randomized controlled trials that were not included in the reviews identified. In vivo and in situ studies yielded mixed results. RESULTS: In situ studies indicated greater efficacy of casein phosphopeptide - amorphous calcium phosphate in comparison with placebo. Whereas, in vivo studies demonstrated different findings CONCLUSION: Casein phosphopeptide - amorphous calcium phosphate had a performance equivalent to or greater efficacy than placebo; fluoride was more effective than the casein complex; casein phosphopeptide - amorphous calcium phosphate associated with fluoride showed better or equivalent performance to that of placebo. In view of available evidence, it was not possible to generalize the indication of casein phosphopeptide - amorphous calcium phosphate for preventing dental caries. Further studies on the preventive effect and longer treatment applications are recommended.

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