Four New Prenylated Flavonoids, Glyasperins A, B, C, and D from the Roots of Glycyrrhiza aspera

Heterocycles ◽  
1992 ◽  
Vol 34 (3) ◽  
pp. 575 ◽  
Author(s):  
Taro Nomura ◽  
Lu Zeng ◽  
Toshio Fukai ◽  
Ru-Yi Zhang ◽  
Zhi-Cen Lou
Keyword(s):  
Prenylated Flavonoids

New cytotoxic prenylated flavonoids from Commiphora opobalsamum stem bark

Planta Medica ◽  
2016 ◽  
Vol 81 (S 01) ◽  
pp. S1-S381
Author(s):  
AA El-Gamal ◽  
SM Al-Massarani ◽  
WM Abdel-Mageed ◽  
A El-Shaibany ◽  
HM Al-Mahbashi ◽  
...  
Keyword(s):  
Stem Bark ◽  
Prenylated Flavonoids

Killing two birds with one stone – Prenylated flavonoids disrupt the lethal synergism of influenza A viruses and pneumococci

Planta Medica ◽  
2016 ◽  
Vol 81 (S 01) ◽  
pp. S1-S381
Author(s):  
U Grienke ◽  
M Richter ◽  
E Walther ◽  
A Hoffmann ◽  
J Kirchmair ◽  
...  
Keyword(s):  
Influenza A ◽  
Influenza A Viruses ◽  
Prenylated Flavonoids

scholarly journals Prenylated Flavonoids and C-15 Isoprenoid Analogues with Antibacterial Properties from the Whole Plant of Imperata cylindrica (L.) Raeusch (Gramineae)

Molecules ◽  
2021 ◽  
Vol 26 (16) ◽  
pp. 4717
Author(s):  
Romeo Nago ◽  
Paul Nayim ◽  
Armelle Mbaveng ◽  
James Mpetga ◽  
Gabin Bitchagno ◽  
...  
Keyword(s):  
Silica Gel ◽  
Methanol Extract ◽  
Antibacterial Properties ◽  
Imperata Cylindrica ◽  
Drug Resistant ◽  
Bacterial Strains ◽  
Prenylated Flavonoids ◽  
Whole Plant ◽  
Crude Methanol Extract ◽  
Potential Origin

The local botanical Imperata cylindrica in Cameroon was investigated for its antibacterial potency. The methanol extract afforded a total of seven compounds, including five hitherto unreported compounds comprising three flavonoids (1–3) and two C-15 isoprenoid analogues (4 and 5) together with known derivatives (6 and 7). The novelty of the flavonoids was related to the presence of both methyl and prenyl groups. The potential origin of the methyl in the flavonoids is discussed, as well as the chemophenetic significance of our findings. Isolation was performed over repeated silica gel and Sephadex LH-20 column chromatography and the structures were elucidated by (NMR and MS). The crude methanol extract and isolated compounds showed considerable antibacterial potency against a panel of multi-drug resistant (MDR) bacterial strains. The best MIC values were obtained with compound (2) against S. aureus ATCC 25923 (32 µg/mL) and MRSA1 (16 µg/mL).

Prenylated flavonoids, promising nutraceuticals with impressive biological activities

2015 ◽  
Vol 44 (1) ◽  
pp. 93-104 ◽  
Author(s):  
Xiaoman Yang ◽  
Yueming Jiang ◽  
Jiali Yang ◽  
Jirui He ◽  
Jian Sun ◽  
...  
Keyword(s):  
Biological Activities ◽  
Prenylated Flavonoids

ChemInform Abstract: Mass Spectrometry of Prenylated Flavonoids

ChemInform ◽  
2010 ◽  
Vol 23 (22) ◽  
pp. no-no
Author(s):  
M. TAKAYAMA ◽  
T. FUKAI ◽  
Y. HANO ◽  
T. NOMURA
Keyword(s):  
Mass Spectrometry ◽  
Prenylated Flavonoids

Prenylated flavonoids from seeds of Calopogonium mucunoides

1982 ◽  
Vol 21 (2) ◽  
pp. 488-489 ◽  
Author(s):  
Marilia O.daS. Pereira ◽  
Edna C. Fantine ◽  
José R. de Sousa
Keyword(s):  
Prenylated Flavonoids ◽  
Calopogonium Mucunoides

ChemInform Abstract: Cytotoxic Prenylated Flavonoids from the Stem Bark of Maackia amurensis.

ChemInform ◽  
2009 ◽  
Vol 40 (36) ◽  
Author(s):  
Xiong Li ◽  
Dong Wang ◽  
Ming-yu Xia ◽  
Zhi-hui Wang ◽  
Wei-ning Wang ◽  
...  
Keyword(s):  
Stem Bark ◽  
Prenylated Flavonoids ◽  
Maackia Amurensis

scholarly journals LaPT2 Gene Encodes a Flavonoid Prenyltransferase in White Lupin

2021 ◽  
Vol 12 ◽  
Author(s):  
Jinyue Liu ◽  
Yaying Xia ◽  
Wenbo Jiang ◽  
Guoan Shen ◽  
Yongzhen Pang
Keyword(s):  
Plant Defense ◽  
Human Health ◽  
Fluorescent Protein ◽  
Lupinus Albus ◽  
Yeast Cells ◽  
White Lupin ◽  
In Planta ◽  
Strong Activity ◽  
Prenylated Flavonoids ◽  
Flavonoid Compounds

Legume plants are rich in prenylated flavonoid compounds, which play an important role in plant defense and human health. In the present study, we identified a prenyltransferase (PT) gene, named LaPT2, in white lupin (Lupinus albus), which shows a high identity and close relationship with the other known PT genes involved in flavonoid prenylation in planta. The recombinant LaPT2 protein expressed in yeast cells exhibited a relatively strong activity toward several flavonols (e.g., kaempferol, quercetin, and myricetin) and a relatively weak activity toward flavanone (naringenin). In addition, the recombinant LaPT2 protein was also active toward several other types of flavonoids, including galangin, morin, 5-deoxyquercetin, 4'-O-methylkaempferol, taxifolin, and aromadendrin, with distinct enzymatic affinities. The LaPT2 gene was preferentially expressed in the roots, which is consistent with the presence of prenylated flavonoid kaempferol in the roots. Moreover, we found that the expression level of LaPT2 paralleled with those of LaF3H1 and LaFLS2 genes that were relatively higher in roots and lower in leaves, suggesting that they were essential for the accumulation of prenylated flavonoid kaempferol in roots. The deduced full-length LaPT2 protein and its signal peptide fused with a green fluorescent protein (GFP) are targeted to plastids in the Arabidopsis thaliana protoplast. Our study demonstrated that LaPT2 from white lupin is responsible for the biosynthesis of prenylated flavonoids, in particular flavonols, which could be utilized as phytoalexin for plant defense and bioactive flavonoid compounds for human health.

Prenylated flavonoids from Commiphora opobalsamum stem bark

2017 ◽  
Vol 141 ◽  
pp. 80-85 ◽  
Author(s):  
Ali A. El-Gamal ◽  
Shaza M. Al-Massarani ◽  
Wael M. Abdel-Mageed ◽  
Amina El-Shaibany ◽  
Hassan M. Al-Mahbashi ◽  
...  
Keyword(s):  
Stem Bark ◽  
Prenylated Flavonoids

Effect of prenylated flavonoids and chalcones isolated from Artocarpus species on platelet aggregation in human whole blood

2010 ◽  
Vol 64 (3) ◽  
pp. 365-369 ◽  
Author(s):  
Ibrahim Jantan ◽  
Yusyila H. Mohd Yasin ◽  
Shajarahtunnur Jamil ◽  
Hasnah Sirat ◽  
Norazah Basar
Keyword(s):  
Platelet Aggregation ◽  
Whole Blood ◽  
Human Whole Blood ◽  
Prenylated Flavonoids
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