Estimate of the risk of radiation-induced cancers after linear-accelerator-based breast-cancer radiotherapy

2013 ◽  
Vol 63 (1) ◽  
pp. 97-103 ◽  
Author(s):  
Eui Kwan Koh ◽  
Jungju Seo ◽  
Tae Seong Baek ◽  
Eun Ji Chung ◽  
Myonggeun Yoon ◽  
...  
2019 ◽  
Vol 186 (2-3) ◽  
pp. 381-385
Author(s):  
Pavel Kundrát ◽  
Cristoforo Simonetto ◽  
Markus Eidemüller ◽  
Julia Remmele ◽  
Hannes Rennau ◽  
...  

Abstract Breast cancer radiotherapy may in the long term lead to radiation-induced secondary cancer or heart disease. These health risks hugely vary among patients, partially due to anatomy-driven differences in doses deposited to the heart, ipsilateral lung and contralateral breast. We identify four anatomic features that largely cover these dosimetric variations to enable personalized risk estimates. For three exemplary, very different risk scenarios, the given parameter set reproduces 63–74% of the individual risk variability for left-sided breast cancer patients. These anatomic features will be used in the PASSOS software to support decision processes in breast-cancer therapy.


2020 ◽  
Vol 152 ◽  
pp. 103-110 ◽  
Author(s):  
Ebbe Laugaard Lorenzen ◽  
Jens Christian Rehammar ◽  
Maj-Britt Jensen ◽  
Marianne Ewertz ◽  
Carsten Brink

2018 ◽  
Vol 127 ◽  
pp. S733
Author(s):  
M. Loos ◽  
K.J. Borm ◽  
M. Oechsner ◽  
D. Paepke ◽  
S.E. Combs ◽  
...  

2018 ◽  
Vol 53 (1) ◽  
pp. 1-5 ◽  
Author(s):  
Tanja Marinko

AbstractBackgroundBreast cancer is the second most common cancer worldwide. Thanks to the modern oncological treatments, disease specific survival has improved throughout the last decades. The number of breast cancer survivors has been increasing, and more and more attention has been paid to the breast cancer treatment side effects. Whereas there are many data regarding ischemic heart disease after radiotherapy for breast cancer, there is not much data in the literature about the incidence and clinical meaning of pericardial disease after breast cancer radiotherapy.ConclusionsAlthough radiation-induced pericarditis is the earliest form of radiation-induced cardiovascular disease after irradiation of the heart, it seems that in clinical practice, especially by using modern radiotherapy treatment techniques, it is underdiagnosed because patients are mostly asymptomatic. In some cases, especially in its late form and after multimodal systemic oncological treatment in combination with radiotherapy, it could be presented in severe form and life threatening. Treatment modalities for radiation-induced pericardial diseases are the same as in the non-irradiated population, but in the irradiated patients, surgery may be difficult.


2006 ◽  
Vol 51 (3) ◽  
pp. L1-L9 ◽  
Author(s):  
Ioannis Tsougos ◽  
Panayiotis Mavroidis ◽  
Kyriaki Theodorou ◽  
J Rajala ◽  
M A Pitkänen ◽  
...  

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