scholarly journals A RESECTED CASE OF INTRADUCTAL PAPILLARY NEOPLASM OF BILE DUCT WITH HEPATOLITHIASIS PRESENTED WITH LIMITED DILATION OF INTRAHEPATIC BILE DUCT

2008 ◽  
Vol 69 (12) ◽  
pp. 3234-3239 ◽  
Author(s):  
Toyoo NITTA ◽  
Yoshihiro SAKAI ◽  
Tomohiro MIZUTANI ◽  
Tomohiro SIMIZU ◽  
Toshiyuki MIYAHARA ◽  
...  
2019 ◽  
Vol 27 (8) ◽  
pp. 900-906
Author(s):  
Genki Usui ◽  
Hirotsugu Hashimoto ◽  
Masashi Kusakabe ◽  
Go Shirota ◽  
Yoshiya Sugiura ◽  
...  

Carcinosarcomas with elements of cholangiocarcinoma and sarcoma are rare and have a poor prognosis. The spreading pattern and radiological findings of these lesions remain unclear. A 74-year-old man presented with a high γ-glutamyl transferase level. Magnetic resonance imaging revealed dilation of the right intrahepatic and common bile ducts, consistent with an intraductal papillary neoplasm of the bile duct (IPNB), and diffusion-weighted imaging (DWI) indicated an area of high signal intensity in the intrahepatic bile duct. Bile duct biopsy yielded a small amount of atypical spindle cells, and the patient underwent a right hepatectomy. Microscopically, the tumor contained cholangiocarcinoma and sarcomatous components, including osteosarcoma and leiomyosarcoma, leading to a diagnosis of intrahepatic carcinosarcoma. The tumor spread primarily through the intrahepatic bile duct. An accurate radiological diagnosis of carcinosarcoma was challenging, given the apparent similarities with IPNB. The findings from DWI and pathology of a bile duct biopsy may assist with preoperative diagnosis.


2016 ◽  
Vol 2016 ◽  
pp. 1-6 ◽  
Author(s):  
Vor Luvira ◽  
Ake Pugkhem ◽  
Theerawee Tipwaratorn ◽  
Yaovalux Chamgramol ◽  
Chawalit Pairojkul ◽  
...  

Intraductal papillary neoplasm of the bile duct (IPNB) is a specific type of bile duct tumor. It has been proposed that it could be the biliary counterpart of the intraductal papillary neoplasm of the pancreas (IPMN-P). This hypothesis is supported by the presence of simultaneous intraductal tumors of both the bile duct and pancreas. There have been five reports of patients with simultaneous IPNB and IPMN-P. In all of these cases, biliary involvement was limited to the intrahepatic and perihilar bile duct, which had characteristics similar to IPMN-P and usually had slow progression in nature. Herein, we present the first case of extensive intraductal neoplasm involving the extrahepatic bile duct, intrahepatic bile duct, and entire length of the pancreas with a poor outcome, even after being treated aggressively with radical surgery and adjuvant chemotherapy. Additionally, we summarize previous case reports of simultaneous intraductal lesions of the bile duct and pancreas.


2020 ◽  
Vol 6 (1) ◽  
Author(s):  
Rumi Matono ◽  
Mizuki Ninomiya ◽  
Kazutoyo Morita ◽  
Takahiro Tomino ◽  
Yumi Oshiro ◽  
...  

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