Specific induction of apoptosis by 1,8-cineole in two human leukemia cell lines, but not a in human stomach cancer cell line

2002 ◽  
Author(s):  
H. Moteki ◽  
H. Hibasami ◽  
Y. Yamada ◽  
H. Katsuzaki ◽  
K. Imai ◽  
...  
Keyword(s):  
Cell Line ◽  
Stomach Cancer ◽  
Leukemia Cell ◽  
Cancer Cell Line ◽  
Human Stomach ◽  
Human Leukemia ◽  
Leukemia Cell Lines ◽  
Specific Induction ◽  
Induction Of Apoptosis ◽  
Human Stomach Cancer

Biological effects of Tween-80 in combination with hyperthermia on human stomach cancer cell line BGC-823

1994 ◽  
Vol 6 (4) ◽  
pp. 252-258 ◽  
Author(s):  
Huchuan Yang ◽  
Yaoqin Yang ◽  
Huihong Tao ◽  
Junyi Zhou ◽  
Yongde Wang
Keyword(s):  
Cell Line ◽  
Stomach Cancer ◽  
Cancer Cell ◽  
Biological Effects ◽  
Cancer Cell Line ◽  
Tween 80 ◽  
Human Stomach ◽  
Human Stomach Cancer

New cancer cachexia rat model generated by implantation of a peritoneal dissemination-derived human stomach cancer cell line

2014 ◽  
Vol 306 (4) ◽  
pp. E373-E387 ◽  
Author(s):  
Kiyoshi Terawaki ◽  
Yumi Sawada ◽  
Yohei Kashiwase ◽  
Hirofumi Hashimoto ◽  
Mitsuhiro Yoshimura ◽  
...  
Keyword(s):  
Weight Loss ◽  
Cell Line ◽  
Stomach Cancer ◽  
Rat Model ◽  
Cancer Cachexia ◽  
Peritoneal Dissemination ◽  
Cancer Cell Line ◽  
Human Stomach ◽  
Mrna Levels ◽  
Human Stomach Cancer

Cancer cachexia (CC), a syndrome characterized by anorexia and body weight loss due to low fat-free mass levels, including reduced musculature, markedly worsens patient quality of life. Although stomach cancer patients have the highest incidence of cachexia, few experimental models for the study of stomach CC have been established. Herein, we developed stomach CC animal models using nude rats subcutaneously implanted with two novel cell lines, i.e., MKN45c185, established from the human stomach cancer cell line MKN-45, and 85As2, derived from peritoneal dissemination of orthotopically implanted MKN45c185 cells in mice. Both CC models showed marked weight loss, anorexia, reduced musculature and muscle strength, increased inflammatory markers, and low plasma albumin levels; however, CC developed earlier and was more severe in rats implanted with 85As2 than in those implanted with MKN45cl85. Moreover, human leukemia inhibitory factor (LIF), a known cachectic factor, and hypothalamic orexigenic peptide mRNA levels increased in the models, whereas hypothalamic anorexigenic peptide mRNA levels decreased. Surgical removal of the tumor not only abolished cachexia symptoms but also reduced plasma LIF levels to below detectable limits. Importantly, oral administration of rikkunshito, a traditional Japanese medicine, substantially ameliorated CC-related anorexia and body composition changes. In summary, our novel peritoneal dissemination-derived 85As2 rat model developed severe cachexia, possibly caused by LIF from cancer cells, that was ameliorated by rikkunshito. This model should provide a useful tool for further study into the mechanisms and treatment of stomach CC.

scholarly journals A flavonoid compound fromChrysosplenium nudicauleinhibits growth and induces apoptosis of the human stomach cancer cell line SGC-7901

2015 ◽  
Vol 54 (7) ◽  
pp. 1133-1139 ◽  
Author(s):  
Yanping Luo ◽  
Hongjuan Yu ◽  
Yunshang Yang ◽  
Weihua Tian ◽  
Kaizhong Dong ◽  
...  
Keyword(s):  
Cell Line ◽  
Stomach Cancer ◽  
Cancer Cell ◽  
Cancer Cell Line ◽  
Human Stomach ◽  
Flavonoid Compound ◽  
Human Stomach Cancer

scholarly journals The Anti-tumor Activity of Vitamin C via the Increase of Fas (CD95) and MHC I Expression on Human Stomach Cancer Cell Line, SNU1

2011 ◽  
Vol 11 (4) ◽  
pp. 210 ◽  
Author(s):  
Yeonsil Yu ◽  
Seyeon Bae ◽  
Hyemin Kim ◽  
Yejin Kim ◽  
Nag Bum Chu ◽  
...  
Keyword(s):  
Vitamin C ◽  
Cell Line ◽  
Stomach Cancer ◽  
Cancer Cell ◽  
Cancer Cell Line ◽  
Human Stomach ◽  
Mhc I ◽  
Human Stomach Cancer ◽  
Anti Tumor Activity

Induction of Apoptosis by Xanthones from Mangosteen in Human Leukemia Cell Lines

2003 ◽  
Vol 66 (8) ◽  
pp. 1124-1127 ◽  
Author(s):  
Kenji Matsumoto ◽  
Yukihiro Akao ◽  
Emi Kobayashi ◽  
Kenji Ohguchi ◽  
Tetsuro Ito ◽  
...  
Keyword(s):  
Cell Lines ◽  
Leukemia Cell ◽  
Human Leukemia ◽  
Human Leukemia Cell ◽  
Leukemia Cell Lines ◽  
Induction Of Apoptosis

Effects of glycolic acid on the induction of apoptosis via caspase-3 activation in human leukemia cell line (HL-60)

2004 ◽  
Vol 42 (11) ◽  
pp. 1777-1784 ◽  
Author(s):  
Jen-Hung Yang ◽  
Chi-Chung Chou ◽  
Ya-Wen Cheng ◽  
Lee-Yan Sheen ◽  
Ming-Chi Chou ◽  
...  
Keyword(s):  
Cell Line ◽  
Glycolic Acid ◽  
Caspase 3 ◽  
Leukemia Cell ◽  
Leukemia Cell Line ◽  
Human Leukemia ◽  
Human Leukemia Cell ◽  
Human Leukemia Cell Line ◽  
Induction Of Apoptosis
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