Downregulation of the β1 adrenergic receptor in the myocardium results in insensitivity to metoprolol and reduces blood pressure in spontaneously hypertensive rats

Yun Huang; Xiao-Li Liu; Jia Wen; Li-Hua Huang; Yao Lu; Ru-Jia Miao; Xing Liu; Ying Li; Xiao-Wei Xing; Hong Yuan

doi:10.3892/mmr.2016.6038

Downregulation of the β1 adrenergic receptor in the myocardium results in insensitivity to metoprolol and reduces blood pressure in spontaneously hypertensive rats

Molecular Medicine Reports ◽

10.3892/mmr.2016.6038 ◽

2016 ◽

Vol 15 (2) ◽

pp. 703-711 ◽

Cited By ~ 3

Author(s):

Yun Huang ◽

Xiao-Li Liu ◽

Jia Wen ◽

Li-Hua Huang ◽

Yao Lu ◽

...

Keyword(s):

Blood Pressure ◽

Adrenergic Receptor ◽

Spontaneously Hypertensive Rats ◽

Hypertensive Rats ◽

Spontaneously Hypertensive

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BLOOD PRESSURE CHANGES IN MATURE SPONTANEOUSLY HYPERTENSIVE RATS (SHR) FOLLOWING ORALLY AND SUBCUTANEOUSLY ADMINISTERED BETA-ADRENERGIC RECEPTOR BLOCKING DRUG

Abstracts ◽

10.1016/b978-0-08-021308-8.51387-9 ◽

1977 ◽

pp. 569

Author(s):

Joseph V. Levy

Keyword(s):

Blood Pressure ◽

Adrenergic Receptor ◽

Spontaneously Hypertensive Rats ◽

Blocking Drug ◽

Hypertensive Rats ◽

Beta Adrenergic Receptor ◽

Beta Adrenergic ◽

Spontaneously Hypertensive ◽

Receptor Blocking ◽

Pressure Changes

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Antisense Inhibition of β 1 -Adrenergic Receptor mRNA in a Single Dose Produces a Profound and Prolonged Reduction in High Blood Pressure in Spontaneously Hypertensive Rats

Circulation ◽

10.1161/01.cir.101.6.682 ◽

2000 ◽

Vol 101 (6) ◽

pp. 682-688 ◽

Cited By ~ 29

Author(s):

Yuan Clare Zhang ◽

Jonathan D. Bui ◽

Leping Shen ◽

M. Ian Phillips

Keyword(s):

Blood Pressure ◽

Single Dose ◽

High Blood Pressure ◽

Adrenergic Receptor ◽

Spontaneously Hypertensive Rats ◽

Antisense Inhibition ◽

Hypertensive Rats ◽

Spontaneously Hypertensive ◽

Receptor Mrna

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Different Effects on Inhibition of Cardiac Hypertrophy in Spontaneously Hypertensive Rats by Monotherapy and Combination Therapy of Adrenergic Receptor Antagonists and/or the Angiotensin II Type 1 Receptor Blocker under Comparable Blood Pressure Reduction

Hypertension Research ◽

10.1291/hypres.28.79 ◽

2005 ◽

Vol 28 (1) ◽

pp. 79-87 ◽

Cited By ~ 14

Author(s):

Takae ASAI ◽

Toshio KUSHIRO ◽

Hirotaka FUJITA ◽

Katsuo KANMATSUSE

Keyword(s):

Blood Pressure ◽

Angiotensin Ii ◽

Combination Therapy ◽

Adrenergic Receptor ◽

Spontaneously Hypertensive Rats ◽

Blood Pressure Reduction ◽

Pressure Reduction ◽

Hypertensive Rats ◽

Spontaneously Hypertensive

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GW27-e0227 Downregulation of the β1 adrenergic receptor in myocardium by AAV9-shRNA-ADRB1-ZsGreen injection reduce blood pressure in spontaneously hypertensive rats

Journal of the American College of Cardiology ◽

10.1016/j.jacc.2016.07.024 ◽

2016 ◽

Vol 68 (16) ◽

pp. C7 ◽

Cited By ~ 1

Author(s):

Wen Gaiyan ◽

Hong Yuan

Keyword(s):

Blood Pressure ◽

Adrenergic Receptor ◽

Spontaneously Hypertensive Rats ◽

Reduce Blood Pressure ◽

Hypertensive Rats ◽

Spontaneously Hypertensive

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Basic research of beta1-adrenergic receptor gene methylation on the different expression and correlation with blood pressure in spontaneously hypertensive rats

International Journal of Cardiology ◽

10.1016/j.ijcard.2011.08.744 ◽

2011 ◽

Vol 152 ◽

pp. S82-S83

Author(s):

Hong Yuan ◽

Xia Du ◽

Zhijun Huang ◽

Xiaowei Xing ◽

Guoping Yang ◽

...

Keyword(s):

Blood Pressure ◽

Adrenergic Receptor ◽

Spontaneously Hypertensive Rats ◽

Receptor Gene ◽

Basic Research ◽

Hypertensive Rats ◽

Gene Methylation ◽

Spontaneously Hypertensive ◽

Adrenergic Receptor Gene

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L-003 BETA1-ADRENERGIC RECEPTOR GENE METHYLATION AND CORRELATION WITH BLOOD PRESSURE IN SPONTANEOUSLY HYPERTENSIVE RATS

Journal of Hypertension ◽

10.1097/01.hjh.0000408084.23097.64 ◽

2011 ◽

Vol 29 ◽

pp. e35

Author(s):

Yan Peng ◽

Xia Du ◽

Hong Yuan ◽

Zhi-Jun Huang ◽

Xiao-Wei Xing

Keyword(s):

Blood Pressure ◽

Adrenergic Receptor ◽

Spontaneously Hypertensive Rats ◽

Receptor Gene ◽

Hypertensive Rats ◽

Gene Methylation ◽

Spontaneously Hypertensive ◽

Adrenergic Receptor Gene

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An experimental study in reducing blood pressure in spontaneously hypertensive rats through extracellular signal-regulated kinase inhibition

Cell Biology International ◽

10.1042/cbi034s031b ◽

2010 ◽

Vol 34 (8) ◽

pp. S31-S31

Author(s):

Li Jing ◽

Jian‑zhong Zhang ◽

Jin‑ping Sun ◽

Xin An ◽

Feng‑ying Guo ◽

...

Keyword(s):

Blood Pressure ◽

Experimental Study ◽

Spontaneously Hypertensive Rats ◽

Hypertensive Rats ◽

Kinase Inhibition ◽

Spontaneously Hypertensive ◽

Extracellular Signal Regulated Kinase ◽

Extracellular Signal

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Improving Effect of Powders of Cooked Soybean and Chongkukjang on Blood Pressure and Lipid Metabolism in Spontaneously Hypertensive Rats

Journal of the Korean Society of Food Science and Nutrition ◽

10.3746/jkfn.2003.32.6.899 ◽

2003 ◽

Vol 32 (6) ◽

pp. 899-905 ◽

Cited By ~ 33

Keyword(s):

Blood Pressure ◽

Lipid Metabolism ◽

Spontaneously Hypertensive Rats ◽

Hypertensive Rats ◽

Spontaneously Hypertensive

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Spent Hen Muscle Protein Hydrolysate Reduces Blood Pressure in Spontaneously Hypertensive Rats

10.21748/am20.159 ◽

2020 ◽

Author(s):

Hingbing Fan ◽

Jianping Wu

Keyword(s):

Blood Pressure ◽

Spontaneously Hypertensive Rats ◽

Muscle Protein ◽

Protein Hydrolysate ◽

Hypertensive Rats ◽

Spontaneously Hypertensive ◽

Spent Hen

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Comparison of Effect of Endothelin Antagonism and Angiotensin-Converting Enzyme Inhibition on Blood Pressure and Vascular Structure in Spontaneously Hypertensive Rats Treated With N ω -Nitro- l -Arginine Methyl Ester

Hypertension ◽

10.1161/01.hyp.28.2.188 ◽

1996 ◽

Vol 28 (2) ◽

pp. 188-195 ◽

Cited By ~ 21

Author(s):

Jin-S. Li ◽

Li Y. Deng ◽

Kevin Grove ◽

Christian F. Deschepper ◽

Ernesto L. Schiffrin

Keyword(s):

Blood Pressure ◽

Methyl Ester ◽

Angiotensin Converting Enzyme ◽

Spontaneously Hypertensive Rats ◽

Angiotensin Converting Enzyme Inhibition ◽

Vascular Structure ◽

Converting Enzyme ◽

Hypertensive Rats ◽

Spontaneously Hypertensive ◽

Converting Enzyme Inhibition

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