scholarly journals Application of adipose-derived stromal cells in fat grafting: Basic science and literature review

2017 ◽  
Vol 14 (3) ◽  
pp. 2415-2423 ◽  
Author(s):  
Margarita Moustaki ◽  
Othon Papadopoulos ◽  
Christos Verikokos ◽  
Dimitrios Karypidis ◽  
Dhalia Masud ◽  
...  
Keyword(s):  
Literature Review ◽  
Stromal Cells ◽  
Basic Science ◽  
Fat Grafting ◽  
Science And Literature ◽  
Adipose Derived Stromal Cells

scholarly journals Characterization of Human Knee and Chin Adipose-Derived Stromal Cells

2015 ◽  
Vol 2015 ◽  
pp. 1-11 ◽  
Author(s):  
Magali Kouidhi ◽  
Phi Villageois ◽  
Carine M. Mounier ◽  
Corinne Ménigot ◽  
Yves Rival ◽  
...  
Keyword(s):  
Stromal Cells ◽  
Expression Profiles ◽  
Donor Site ◽  
Subcutaneous Fat ◽  
Gene Expression Profiles ◽  
Fat Grafting ◽  
Human Knee ◽  
Fat Depots ◽  
Adipose Derived Stromal Cells ◽  
Molecular Matching

Animal study findings have revealed that individual fat depots are not functionally equivalent and have different embryonic origins depending on the anatomic location. Mouse bone regeneration studies have also shown that it is essential to match theHoxcode of transplanted cells and host tissues to achieve correct repair. However, subcutaneous fat depots from any donor site are often used in autologous fat grafting. Our study was thus carried out to determine the embryonic origins of human facial (chin) and limb (knee) fat depots and whether they had similar features and molecular matching patterns. Paired chin and knee fat depots were harvested from 11 subjects and gene expression profiles were determined by DNA microarray analyses. Adipose-derived stromal cells (ASCs) from both sites were isolated and analyzed for their capacity to proliferate, form clones, and differentiate. Chin and knee fat depots expressed a differentHOXcode and could have different embryonic origins. ASCs displayed a different phenotype, with chin-ASCs having the potential to differentiate into brown-like adipocytes, whereas knee-ASCs differentiated into white adipocytes. These results highlighted different features for these two fat sites and indicated that donor site selection might be an important factor to be considered when applying adipose tissue in cell-based therapies.

Systemic Administration of Adipose-Derived Stromal Cells Concurrent with Fat Grafting

2019 ◽  
Vol 143 (5) ◽  
pp. 973e-982e ◽  
Author(s):  
Ki Yong Hong ◽  
Il-Kug Kim ◽  
Seong Oh Park ◽  
Ung Sik Jin ◽  
Hak Chang
Keyword(s):  
Stromal Cells ◽  
Fat Grafting ◽  
Systemic Administration ◽  
Adipose Derived Stromal Cells

Fluorescent Immortalized Human Adipose Derived Stromal Cells (hASCs-TS/GFP+) for Studying Cell Drug Delivery Mediated by Microvesicles

2017 ◽  
Vol 17 (11) ◽  
Author(s):  
Valentina Cocce ◽  
Luigi Balducci ◽  
Maria L. Falchetti ◽  
Luisa Pascucci ◽  
Emilio Ciusani ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Stromal Cells ◽  
Adipose Derived Stromal Cells
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