scholarly journals HMGB1 as a therapeutic target in spinal cord injury: A hypothesis for novel therapy development

2011 ◽  
Vol 2 (5) ◽  
pp. 767-770 ◽  
Author(s):  
KIYOSHI KIKUCHI ◽  
HISAAKI UCHIKADO ◽  
NAOKI MIURA ◽  
YOKO MORIMOTO ◽  
TAKASHI ITO ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Therapeutic Target ◽  
Novel Therapy ◽  
Cord Injury ◽  
Therapy Development

scholarly journals Complement Plays an Important Role in Spinal Cord Injury and Represents a Therapeutic Target for Improving Recovery following Trauma

2006 ◽  
Vol 169 (3) ◽  
pp. 1039-1047 ◽  
Author(s):  
Fei Qiao ◽  
Carl Atkinson ◽  
Hongbin Song ◽  
Ravinder Pannu ◽  
Inderjit Singh ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Therapeutic Target ◽  
Cord Injury

scholarly journals Cytosolic phospholipase A 2 protein as a novel therapeutic target for spinal cord injury

2014 ◽  
Vol 75 (5) ◽  
pp. 644-658 ◽  
Author(s):  
Nai‐Kui Liu ◽  
Ling‐Xiao Deng ◽  
Yi Ping Zhang ◽  
Qing‐Bo Lu ◽  
Xiao‐Fei Wang ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Therapeutic Target ◽  
Phospholipase A ◽  
Cytosolic Phospholipase ◽  
Cord Injury ◽  
Novel Therapeutic ◽  
Phospholipase A 2

scholarly journals Stem Cells in Spinal Cord Injury

2008 ◽  
Vol 24 (4-5) ◽  
pp. 239-250 ◽  
Author(s):  
Jean R. Wrathall ◽  
Judith M. Lytle
Keyword(s):  
Spinal Cord ◽  
Stem Cells ◽  
Spinal Cord Injury ◽  
Neural Stem Cells ◽  
Therapeutic Target ◽  
Proliferative Response ◽  
Traumatic Injury ◽  
Functional Deficits ◽  
Cord Injury ◽  
Adult Spinal Cord

Traumatic injury to the adult spinal cord results in a massive loss of cells and permanent functional deficits. However, recent studies demonstrate that there is a proliferative response of endogenous glial precursors and progenitors and perhaps also pluripotent neural stem cells. These cells may prove to be an important new therapeutic target to improve recovery after injury to the spinal cord and brain.

scholarly journals TFE3, a potential therapeutic target for Spinal Cord Injury via augmenting autophagy flux and alleviating ER stress

Theranostics ◽  
2020 ◽  
Vol 10 (20) ◽  
pp. 9280-9302
Author(s):  
Kailiang Zhou ◽  
Zhilong Zheng ◽  
Yao Li ◽  
Wen Han ◽  
Jing Zhang ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Er Stress ◽  
Therapeutic Target ◽  
Autophagy Flux ◽  
Potential Therapeutic Target ◽  
Cord Injury

Matrix Metalloproteinases as a Therapeutic Target to Improve Neurologic Recovery After Spinal Cord Injury

2015 ◽  
Author(s):  
Linda J. Noble ◽  
Alpa Mahuvakar ◽  
Thomas Fandel ◽  
Aida F. Martinez ◽  
Jon Levine
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Matrix Metalloproteinases ◽  
Therapeutic Target ◽  
Neurologic Recovery ◽  
Cord Injury
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