scholarly journals Distribution of erythrocyte binding antigen 175 (EBA-175) alleles and ABO blood groups in a hypoendemic area in Senegal

2012 ◽  
Vol 6 (10) ◽  
pp. 727-733 ◽  
Author(s):  
Aida Sadikh Badiane ◽  
Ousmane Sarr ◽  
Awa Bineta Deme ◽  
Ambroise Dioum Ahouidi ◽  
Papa Elhadji Omar Gueye ◽  
...  
Keyword(s):  
Blood Group ◽  
Plasmodium Falciparum Malaria ◽  
Blood Groups ◽  
Abo Blood Groups ◽  
Blood Samples ◽  
Group Type ◽  
Erythrocyte Binding ◽  
Blood Group Type ◽  
First Time ◽  
Uncomplicated Plasmodium Falciparum Malaria

Introduction: The study was conducted to determine for the first time the association between the erythrocyte binding antigen 175 (EBA-175) alleles and ABO blood groups in malaria patients living in Thies, a hypoendemic area in Senegal. Methodology: In 2007, the EBA-175 alleles and blood group types were determined by nested PCR and the Simonin test respectively in blood samples obtained from uncomplicated Plasmodium falciparum malaria positive patients. Results and conclusion: In total, 129 patients were enrolled in the study. The EBA-175 genotyping showed a prevalence of 67.45% for the F-allele, 27.90% for the C-allele and 4.65% of mixed C+F infection. The distribution of the ABO blood group type showed 59.8% for the O group, 19.7% for the A group, 17.2% for the B group, and 3.3% for the AB group. No correlation was noted between the EBA-175 alleles and either the blood group type or parasitemia.

The Relation between the Blood Groups, Rhesus Factor, and Breast Cancer in the Holy Karbala Governorate

2020 ◽  
pp. 31-33
Keyword(s):  
Breast Cancer ◽  
Blood Group ◽  
Type A ◽  
Blood Groups ◽  
Abo Blood Groups ◽  
Group Type ◽  
Rhesus Factor ◽  
Significant Difference ◽  
Healthy Control ◽  
Blood Group Type

The distribution ABO blood groups among patients with breast cancer were as follow: blood group type O (40.8%), blood group type A (25.0%), B (23.7%), and AB (10.4%), for the donor’s healthy control, ABO blood groups percentages were as follow: type O (39.9%) type A (28.1%), type B (22.0%), and type AB (9.9%). There is no significant association between blood types ABO and the breast cancer. (P > 0.05) Rh factor has a significant difference between patients with breast cancer and healthy control (P=0.002). There were significant differences in age categories among patients with breast cancer and controls. (p= 0.000) .

“ASSOCIATION OF ABO & RH BLOOD GROUPS WITH HEPATITIS, HIV AND SYPHILIS INFECTIONS IN HEALTHY BLOOD DONORS AT TERTIARY CARE CENTRE”.

2021 ◽  
pp. 68-70
Author(s):  
Sonal Chitroda ◽  
Neha Patel ◽  
Pinal Solanki
Keyword(s):  
Blood Group ◽  
Blood Donors ◽  
Tertiary Care ◽  
Blood Groups ◽  
Care Hospital ◽  
Tertiary Care Centre ◽  
Group Type ◽  
Increased Risk ◽  
High Prevalence ◽  
Blood Group Type

Background: People from certain blood groups are more prone to develop infections transmitted by blood transfusion. In order to improve the management of such infections some hypothesis suggests that genetic predispositions like ABO and Rh blood groups would inuence the occurrence of such infections. Hence the present study aims to assess any possible associations of ABO & Rh blood groups with Hepatitis, HIV & syphilis infections in healthy blood donors. This was a retrospective study in heal Methods: thy blood donors of tertiary care hospital enrolled during years 2016 to 2020. Blood samples from total 34015 donors were screened for blood grouping & serology of HIV, Hepatitis & Syphilis. Result: Out of total donors only 171 donors were found positive for transfusion transmitted infections. Hepatitis B virus was found more prevalent compared to other infections. In ABO blood group type “B” and in Rh blood group type “Positive” was found more prevalent in donors. But it did not show any signicant association with transfusion transmitted infections. Conclusion: High prevalence of HBV infections in blood donors in present study point towards need of public health measures in general population. Undertaking further research to determine the special blood groups as increased risk for categorized donors is recommended.

scholarly journals Are ABO Gene Alleles Responsible for Cardiovascular Diseases and Venous Thromboembolism and Do They Play a Role in COVID?

2021 ◽  
Author(s):  
Dennis J. Cordato ◽  
Wissam Soubra ◽  
Sameer Saleem ◽  
Kaneez Fatima Shad
Keyword(s):  
Coronary Heart Disease ◽  
Heart Disease ◽  
Venous Thromboembolism ◽  
Cardiovascular Diseases ◽  
Factor Viii ◽  
Blood Group ◽  
Blood Groups ◽  
Group Type ◽  
Blood Group Type ◽  
Peripheral Arterial

Cardiovascular diseases (CVD) including coronary heart disease and stroke are leading causes of death and disability globally. Studies of the association between ABO blood groups and CVD have consistently demonstrated an increased risk of coronary heart disease, myocardial infarction, cerebral ischaemic stroke, peripheral arterial disease and venous thromboembolism (VTE) including deep vein thrombosis and pulmonary thromboembolism in patients who possess a non-O blood group type. The most likely mechanism is thought to be the increase in von Willebrand Factor (vWF) and factor VIII levels seen in patients with a non-O blood group. Other postulated mechanisms include elevations in circulating inflammatory markers such as endothelial cell and platelet adhesion molecules in subjects with a non-O blood group. More recently, it has also been recognised that individuals with a non-O blood group type carry a higher risk of SARS-C0V-2 infection and COVID-19 related complications. The increased levels in vWF and factor VIII amongst individuals with a non-O blood group who have contracted SARS-CoV-2 infection may result in an additive thrombophilic effect to that caused by the SARS-CoV-2 virus. Another postulated mechanism is that individuals with an O-blood group are protected by anti-A and B antibodies which possibly inhibit the binding of the SARS-CoV-2 spike protein to lung epithelium angiotensin converting enzyme-2 receptors. There are over 35 minor blood groups on red blood cells, some of which such as Kidd, Lewis and Duffy have been associated with CVD either alone or in combination with a non-O blood group allele(s). However, their role in SARS-CoV-2 infection and mechanism of action for an association with CVD remain unknown. This review explores the relationship between ABO and minor blood groups with CVD and VTE, with a focus on potential mechanisms underlying this relationship and the potential role of ABO blood group types in COVID.

scholarly journals ABO blood group, glycosyltransferase activity and risk of Venous Thrombosis

2020 ◽  
Author(s):  
Manal Ibrahim Kosta ◽  
Pascal Bailly ◽  
Monique Silvy ◽  
Noemie Saut ◽  
Pierre Suchon ◽  
...  
Keyword(s):  
Venous Thrombosis ◽  
Blood Group ◽  
Plasma Levels ◽  
Blood Groups ◽  
Abo Blood Group ◽  
Abo Blood Groups ◽  
Factor Assay ◽  
Von Willebrand ◽  
First Time ◽  
Willebrand Factor

AbstractIntroductionABO blood group influence the risk of venous thrombosis (VT) by modifying A and B glycosyltransferases (AGT and BGT) activities that further modulates Factor VIII (FVIII) and von Willebrand Factor (VWF) plasma levels. The aim of this work was to evaluate the association of plasma GTs activities with VWF/FVIII plasma levels and VT risk in a case-control study.Materials and Methods420 cases were matched with 420 controls for age and ABO blood group. GT activities in plasma were measured using the quantitative transfer of tritiated N-acetylgalactosamine or galactose to the 2’-fucosyl-lactose and expressed in disintegration per minute/30µL of plasma and 2 hours of reaction (dpm/30µL/2H). FVIII and VWF plasma levels were respectively measured using human FVIII-deficient plasma in a 1-stage factor assay and STA LIATEST VWF (Diagnostica Stago).ResultsA and B GT activities were significantly lower in cases than in controls (8119±4027 vs 9682±4177 dpm/30µL/2H, p=2.03 × 10−5, and 4931±2305 vs 5524±2096 dpm/30µL/2H, p=0.043 respectively). This association was observed whatever the ABO blood groups. The ABO A1 blood group was found to explain∼80% of AGT activity. After adjusting for ABO blood groups, AGT activity was not correlated to VWF/FVIII plasma levels. Conversely, there was a moderate correlation (ρ∼0.30) between BGT activity and VWF/ FVIII plasma levels in B blood group carriers.ConclusionThis work showed, for the first time, that GT activities were decreased in VT patients in comparison to controls with the same ABO blood group. The biological mechanisms responsible for this association remained to be determined.

scholarly journals Association of Malaria Parasitaemia with ABO/Rhesus Blood Group among Out-patients of Township Clinic Gwagwalada Abuja, Nigeria

2019 ◽  
pp. 1-7
Author(s):  
Binta Balarabe-Musa ◽  
H. R. Muhammad ◽  
H. Momo ◽  
F. A. Nnadike
Keyword(s):  
Plasmodium Falciparum ◽  
Blood Group ◽  
Malaria Infection ◽  
Blood Groups ◽  
Falciparum Infection ◽  
Abo Blood Groups ◽  
Malaria Parasitaemia ◽  
Blood Samples ◽  
Rhesus Blood Group ◽  
Control Methodology

Aim: This study was carried out to determine association of malaria parasitaemia with ABO/Rhesus blood group. Methodology: A total of 150 blood samples were randomly selected and examined for the presence of Plasmodium falciparum using microscopy, blood group was determined using agglutination technique. Results: A total 92 (61.3%) were found to be infected with P. falciparum, the prevalence was highest among under five (0-10) than older groups, and higher among males 55 (63.2%) than female 37 (58.7%). Majority of the patients were rhesus positive 90(64.3%) while 2(20.0%) were rhesus negative. High percentage of blood group O, 70 (46.7%) was observed, followed by A 39(26.0%), B 34 (22.7%) and AB 7 (4.6%). All ABO blood groups showed varied presence of P. falciparum 51(72.8%), 22(56.4%), 17(50.0%) and 2(28.5%) for O, A, B and AB, respectively. Parasite density was also higher in blood group O 70 (41.69%), followed by B 34 (30.67%), and A 39 (28.09%) then AB 7 (16.84%). Conclusion: It can be concluded that malaria parasitaemia is higher in males than female and in the younger ages than the older ones. Also Blood groups O are the most susceptible to malaria infection and AB are the least infected. However further investigation is needed to clearly establish the association ABO/Rhesus blood groups and P. falciparum infection and the need for intensified control methodology of the disease and education of the populace on the effect of rhesus negative cannot be over emphasized.

scholarly journals Correlation of ABO Blood Groups and Rh Factor with The Severity of Generalized Chronic Periodontitis: Across Sectional Study in Riyadh, Saudi Arabia

2019 ◽  
Vol 7 (4) ◽  
pp. 617-622 ◽  
Author(s):  
Diana Mostafa ◽  
Essam I. Elkhatat ◽  
Pradeep Koppolu ◽  
Muna Mahgoub ◽  
Esam Dhaifullah ◽  
...  
Keyword(s):  
Saudi Arabia ◽  
Blood Group ◽  
Chronic Periodontitis ◽  
Periodontal Diseases ◽  
Blood Groups ◽  
Blood Group Antigens ◽  
Abo Blood Groups ◽  
Sectional Study ◽  
Cross Sectional ◽  
Group I

BACKGROUND: The development of periodontal diseases depends on the presence of causative microorganisms, host immunity and risk factors. Although variability present among the types of periodontal diseases, all are represented to a shared interaction between host and bacteria. ABO blood groups are the most investigated erythrocyte antigen system. However, limited investigations have been conducted to explore the alliance between ABO blood groups and periodontal diseases. AIM: Our purpose was to explore any possible association between the severity of chronic periodontitis with ABO blood groups and Rh factor. METHODS: A cross-sectional study was carried out on 205 patients out of 1126 generalised chronic periodontitis patients (GCP) who were referred to Al-Farabi Colleges, Riyadh, Saudi Arabia. They were categorized into; group I (mild), group II (moderate) and group III (sever). RESULTS: The patients with blood group O were at a greater risk to develop GCP irrespective of its severity, followed by those with blood group A, B, and AB. The dispensation of the Rh factor in all groups exhibited a significantly greater distribution of Rh positive. CONCLUSION: Genetic factors such as ABO blood group antigens may act as a risk influencer that affects the progression and severity of the chronic periodontitis.

scholarly journals Association of ABO blood groups with presentation and outcomes of confirmed SARS CoV-2 infection: A prospective study in the largest COVID-19 dedicated hospital in Bangladesh

PLoS ONE ◽  
2021 ◽  
Vol 16 (4) ◽  
pp. e0249252
Author(s):  
Reaz Mahmud ◽  
Mohammad Aftab Rassel ◽  
Farhana Binte Monayem ◽  
S. K. Jakaria Been Sayeed ◽  
Md Shahidul Islam ◽  
...  
Keyword(s):  
Blood Group ◽  
Blood Groups ◽  
Abo Blood Groups ◽  
Duration Of Symptoms ◽  
Presenting Symptoms ◽  
Blood Group A ◽  
Group I ◽  
Significant Difference ◽  
Group A ◽  
Group Ii

Background Globally, studies have shown conflicting results regarding the association of blood groups with SARS CoV-2 infection. Objective To observe the association between ABO blood groups and the presentation and outcomes of confirmed COVID-19 cases. Design, setting, and participants This was a prospective cohort study of patients with mild-to-moderately severe COVID-19 infections who presented in the COVID-19 unit of Dhaka Medical College Hospital and were enrolled between 01 June and 25 August, 2020. Patients were followed up for at least 30 days after disease onset. We grouped participants with A-positive and A-negative blood groups into group I and participants with other blood groups into group II. Results The cohort included 438 patients; 52 patients were lost to follow-up, five died, and 381 completed the study. The prevalence of blood group A [144 (32.9%)] was significantly higher among COVID-19 patients than in the general population (p < 0.001). The presenting age [mean (SD)] of group I [42.1 (14.5)] was higher than that of group II [38.8 (12.4), p = 0.014]. Sex (p = 0.23) and co-morbidity (hypertension, p = 0.34; diabetes, p = 0.13) did not differ between the patients in groups I and II. No differences were observed regarding important presenting symptoms, including fever (p = 0.72), cough (p = 0.69), and respiratory distress (p = 0.09). There was no significant difference in the median duration of symptoms in the two group (12 days), and conversion to the next level of severity was observed in 26 (20.6%) and 36 patients (13.8%) in group I and II, respectively. However, persistent positivity of RT-PCR at 14 days of initial positivity was more frequent among the patients in group I [24 (19%)] than among those in group II [29 (11.1%)]. Conclusions The prevalence of blood group A was higher among COVID-19 patients. Although ABO blood groups were not associated with the presentation or recovery period of COVID-19, patients with blood group A had delayed seroconversion.

scholarly journals DISTRIBUTION OF ABO AND RH (D) BLOOD GROUPS AMONG BLOOD DONORS IN DISTRICT MARDAN, PAKISTAN

1969 ◽  
Vol 3 (2) ◽  
pp. 318-322
Author(s):  
MUHAMMAD KHALID ◽  
NAILA ASLAM ◽  
MUHAMMAD SIYAR ◽  
RASHID AHMAD
Keyword(s):  
Blood Group ◽  
Blood Donors ◽  
Local Community ◽  
Healthy Adult ◽  
Blood Groups ◽  
Abo Blood Groups ◽  
Cross Sectional ◽  
Group B ◽  
Abo Blood Grouping ◽  
Blood Grouping

OBJECTIVE: To find out the distribution of ABO and Rh (D) blood groups among blood donors in districtMardan and to help transfusion services in the area.STUDY DESIGN: Cross sectional descriptive study.MATERIALS AND METHODS: The study was conducted in DHQ Hospital Mardan from 1st January2012 to 31st December 2012. A total of 2893 healthy adult, blood donors (both volunteer and directed) fromdistrict Mardan were included. Two ml of blood anti-coagulated with EDTA was taken and both ABO andRh (D) blood groups were determined using commercially available anti-sera of Biolaboratories. Thedistribution ofABO and Rh blood groups in the local community were then calculated.RESULTS: Among ABO blood groups “ B” (27.97%) was the most prevalent, followed by “0” (27.93%),“ A” (24.75%) and “ AB” (19.36%). Group Rh positive (94.30%) was more prevalent than Rh negative(5.70%). Similarly 0+ve (26.65%) was most frequent followed by B+ve (26.17%), A+ve (23.16%), AB+ve(18.32%), B've(1.80%),Ave(l.59%),O ve( 1.28%) and ABve( 1.04%).CONCLUSION: Blood group 'B' was most frequent among the ABO blood groups and Rh (D) positiveamong Rh blood groups while0+vewas the most frequent blood group in the study population.KEYWORDS: ABO Blood grouping, Rh (D) blood grouping, Mardan.

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