scholarly journals Evaluating the Effect of Booster Dose of Hepatitis B Vaccine in Low-and Non-Responders Healthcare Workers and the Role of some Host-Related Factors

2011 ◽  
Vol 7 (2) ◽  
pp. 24-28 ◽  
Author(s):  
Chia-Yon
Keyword(s):  
Hepatitis B ◽  
Healthcare Workers ◽  
Booster Dose ◽  
Hepatitis B Vaccine ◽  
Related Factors

Evaluation of the response to a booster dose of hepatitis B vaccine in previously immunized healthcare workers

Vaccine ◽  
2001 ◽  
Vol 19 (28-29) ◽  
pp. 4081-4085 ◽  
Author(s):  
James L Williams ◽  
Carol J Christensen ◽  
Brian J McMahon ◽  
Lisa R Bulkow ◽  
Henry H Cagle ◽  
...  
Keyword(s):  
Hepatitis B ◽  
Healthcare Workers ◽  
Booster Dose ◽  
Hepatitis B Vaccine

scholarly journals Circulating Tfh cell and subsets distribution are associated with low‐responsiveness to hepatitis B vaccination

2021 ◽  
Vol 27 (1) ◽  
Author(s):  
Mingjuan Yin ◽  
Yongzhen Xiong ◽  
Dongmei Liang ◽  
Hao Tang ◽  
Qian Hong ◽  
...  
Keyword(s):  
Hepatitis B ◽  
Hepatitis B Vaccine ◽  
Hepatitis B Vaccination ◽  
Cellular Mechanisms ◽  
Immunological Responses ◽  
Follicular Helper ◽  
Low Responders ◽  
Specific Subset ◽  
Antibody Titers

Abstract Background An estimated 5–10 % of healthy vaccinees lack adequate antibody response following receipt of a standard three-dose hepatitis B vaccination regimen. The cellular mechanisms responsible for poor immunological responses to hepatitis B vaccine have not been fully elucidated to date. Methods There were 61 low responders and 56 hyper responders involved in our study. Peripheral blood samples were mainly collected at D7, D14 and D28 after revaccinated with a further dose of 20 µg of recombinant hepatitis B vaccine. Results We found low responders to the hepatitis B vaccine presented lower frequencies of circulating follicular helper T (cTfh) cells, plasmablasts and a profound skewing away from cTfh2 and cTfh17 cells both toward cTfh1 cells. Importantly, the skewing of Tfh cell subsets correlated with IL-21 and protective antibody titers. Based on the key role of microRNAs involved in Tfh cell differentiation, we revealed miR-19b-1 and miR-92a-1 correlated with the cTfh cell subsets distribution and antibody production. Conclusions Our findings highlighted a decrease in cTfh cells and specific subset skewing contribute to reduced antibody responses in low responders.

scholarly journals A Study of Persistence of Anti-HBs Antibodies after Vaccination with Recombinant Hepatitis B Vaccine in Healthcare Workers

2018 ◽  
Vol 33 (3) ◽  
pp. 117-122
Author(s):  
Sumio IWASAKI ◽  
Reiko OYAMADA ◽  
Tsubasa WATANABE ◽  
Kiyomi HASUIKE ◽  
Sumito NAKAMURA ◽  
...  
Keyword(s):  
Hepatitis B ◽  
Healthcare Workers ◽  
Hepatitis B Vaccine ◽  
Recombinant Hepatitis

Antibody persistence and the effect of a booster dose given 5, 10 or 15years after vaccinating preadolescents with a recombinant hepatitis B vaccine

Vaccine ◽  
2013 ◽  
Vol 31 (3) ◽  
pp. 448-451 ◽  
Author(s):  
Vladimir Gilca ◽  
Gaston De Serres ◽  
Nicole Boulianne ◽  
Donald Murphy ◽  
Philippe De Wals ◽  
...  
Keyword(s):  
Hepatitis B ◽  
Booster Dose ◽  
Hepatitis B Vaccine ◽  
Recombinant Hepatitis ◽  
Antibody Persistence

scholarly journals Evaluation of Immune Response to Hepatitis B Vaccine in Healthcare Workers at a Tertiary Care Hospital

2018 ◽  
Vol 36 (3) ◽  
pp. 397-400
Author(s):  
Praveena Basireddy ◽  
Surekha Avileli ◽  
Nagajyothi Beldono ◽  
Swarna Latha Gundela
Keyword(s):  
Immune Response ◽  
Hepatitis B ◽  
Healthcare Workers ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Hepatitis B Vaccine ◽  
Care Hospital

Impact of the Bloodborne Pathogens Standard on Vaccination of Healthcare Workers with Hepatitis B Vaccine

1995 ◽  
Vol 16 (5) ◽  
pp. 287-291 ◽  
Author(s):  
Tracy B. Agerton ◽  
Francis J. Mahoney ◽  
Louis B. Polish ◽  
Craig N. Shapiro
Keyword(s):  
Hepatitis B ◽  
Healthcare Workers ◽  
Hepatitis B Vaccine ◽  
Bloodborne Pathogens
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