Pachychoroid Spectrum Diseases; Color Fundus Photograph, Fundus Fluorescein Angiography And Indocyanine Green Angiography.

2020 ◽  
pp. 75-80
Keyword(s):  
Indocyanine Green ◽  
Fluorescein Angiography ◽  
Multimodal Imaging ◽  
Choroidal Thickness ◽  
Indocyanine Green Angiography ◽  
Morphological Changes ◽  
Clinical Manifestations ◽  
Fundus Fluorescein Angiography ◽  
Fundus Photographs

The term of pachychoroid spectrum diseases is used to identify a group of diseases that are characterized by increase of choroidal thickness. The increase of choroidal thickness is caused by dilated vascular vessels in Haller’s layer and accompanied by thinning in the choriocapillaris and Sattler’s layer. The presence of characteristic morphological changes including structural and functional choroidal changes is the key pathophysiological basis for the identification of pachychoroid diseases. The spectrum of pachychoroid disease consists of different clinical manifestations that can progress from one to another. Multimodal imaging methods are used in the diagnosis, treatment, and follow-up of these diseases. In this review, color fundus photographs, fundus fluorescein angiography, and indocyanine green angiography characteristics of pachychoroid diseases are discussed.

scholarly journals Fluorescein Angiography, Wide Field Angiography, and Indocyanine Green Angiography in Behcet Uveitis

2018 ◽  
pp. 334-337
Keyword(s):  
Early Diagnosis ◽  
Indocyanine Green ◽  
Fluorescein Angiography ◽  
Indocyanine Green Angiography ◽  
Ocular Involvement ◽  
Wide Field ◽  
Fundus Examination ◽  
Fundus Fluorescein Angiography ◽  
Important Place ◽  
Retinal Periphery

In Behcet's disease, the anterior and posterior segments of the eye may be affected separately or together. Fundus fluorescein angiography should be performed in addition to ophthalmoscopic examination for early diagnosis and treatment of ocular involvement. Fundus fluorescein angiography (FFA) is the gold standard for the evaluation of the retinal vascular system and pathologies. Fundus fluorescein angiography is more sensitive than fundus examination in the detection of vasculitis, and angiographic involvement is always more common than clinical involvement. Fluorescein angiography may reveal leakage from retinal veins in eyes whose visual impression is not affected and the fundus examination is normal. The absence of vascular leakage with fluorescein angiography indicates that the disease is in a completely inactive period. Because of the development of blindness due to posterior segment involvement, early detection of the disease with fundus angiography and the initiation of the treatment is successful in terms of visual prognosis. It has an important place in terms of early activation of patients with FFA in the early diagnosis of eye involvement and follow-up of the disease and treatment. Wide-field imaging angiography imaging of the retinal periphery revealed the importance of lesions in retinal periphery and peripheral areas invisible by standard angiography. The use of indocyanine green angiography in Behcet uveitis is limited.

Indocyanine green angiography imaging findings in artery occlusions

2021 ◽  
pp. 112067212110378
Author(s):  
Ramesh Venkatesh ◽  
Nikitha Gurram Reddy ◽  
Vishma Prabhu ◽  
Pukhraj Rishi ◽  
Arpitha Pereira ◽  
...  
Keyword(s):  
Indocyanine Green ◽  
Multimodal Imaging ◽  
Indocyanine Green Angiography ◽  
Retinal Vessel ◽  
Retinal Artery Occlusion ◽  
Artery Occlusion ◽  
Imaging Features ◽  
Retinal Artery ◽  
Choroidal Perfusion ◽  
Rouleaux Formation

Purpose: To describe the multimodal imaging features including indocyanine green angiography (ICGA) in cases diagnosed clinically as central retinal artery occlusion (CRAO) at its different disease stages. Methods: In this retrospective observational study, patients diagnosed clinically as CRAO or hemi-CRAO were included. All patients underwent multimodal imaging with optical coherence tomography (OCT), fundus fluorescein angiography (FFA) and indocyanine green angiography (ICGA) were studied. Analysis of ICGA images in different stages of artery occlusions and its correlation with accompanying FFA and OCT images was done. Results: Eight such studies in five patients were available for analysis. The most important observation noted on ICGA was the presence of hypercyanescent spots seen during the acute stages of the disease in four of the five cases. The spots were accompanied by retinal vessel staining on FFA in the corresponding region. As the disease showed signs of resolution, the hypercyanescent spots on ICGA and retinal vessel staining on FFA disappeared. The hypercyanescent spots seen on the ICGA were noted due to the red blood cell aggregation or ‘rouleaux’ formation. In addition, choroidal perfusion abnormalities were noted on ICGA in all five cases in the acute stage. Conclusion: Choroidal perfusion changes can be identified in acute phase of retinal artery occlusion. Rouleaux formation in the retinal circulation occurs due to the slowing of the blood flow following artery occlusion. These are seen as hypercyanescent spots in the late phase on ICGA.

Identification of Underlying Causes of Spontaneous Submacular Hemorrhage by Indocyanine Green Angiography

2015 ◽  
Vol 233 (3-4) ◽  
pp. 146-154 ◽  
Author(s):  
Hyesun Kim ◽  
Sung Chul Lee ◽  
Sang Myung Kim ◽  
Ji Hwan Lee ◽  
Hyoung Jun Koh ◽  
...  
Keyword(s):  
Visual Acuity ◽  
Indocyanine Green ◽  
Indocyanine Green Angiography ◽  
Age Related Macular Degeneration ◽  
Fundus Photography ◽  
Submacular Hemorrhage ◽  
Foveal Thickness ◽  
Central Foveal Thickness ◽  
The Mean

Purpose: To investigate the causes of acute spontaneous submacular hemorrhage with indocyanine green angiography (ICGA). Methods: Retrospective observation case series. A total of 51 eyes from 51 patients with newly developed spontaneous submacular hemorrhage were enrolled. Best-corrected visual acuity (BCVA), fundus photography, fluorescein angiography, spectral domain optical coherence tomography (OCT), and ICGA at baseline were analyzed. The extent of hemorrhage using fundus photography, height of hemorrhage, and central foveal thickness measured by OCT was analyzed to compare the diagnostic and nondiagnostic groups. Results: The mean logarithm of the minimum angle of resolution (logMAR) BCVA at presentation was 1.21 ± 0.74 (Snellen equivalent, 20/324); the mean follow-up period was 23.9 ± 23.9 months. The cause of submacular hemorrhage was diagnosed in 43 of 51 eyes (84.3%) based on ICGA at presentation. The initial diagnoses were correct in 93% of eyes. In 3 cases, the initial diagnosis of age-related macular degeneration (AMD) was changed to polypoidal choroidal vasculopathy (PCV) based on follow-up ICGA. The central foveal thickness was significantly greater in the nondiagnostic group (1,102.4 vs. 666.7 μm, respectively; p = 0.008). The most common cause of submacular hemorrhage was neovascular AMD (52.9%), followed by PCV (37.3%), macroaneurysm (5.9%), and lacquer crack (3.9%). The mean final visual acuity was generally worse in patients with submacular hemorrhage with typical AMD (visual acuity 20/618) or PCV (visual acuity 20/240) compared to that in patients with retinal macroaneurysm (visual acuity 20/100) or lacquer crack (visual acuity 20/72). Conclusions: ICGA at initial presentation helps identify causes of submacular hemorrhage, allowing differential treatment approaches that may improve outcomes and safety.

scholarly journals Multimodal Image Analysis in Acquired Vitelliform Lesions and Adult-Onset Foveomacular Vitelliform Dystrophy

2016 ◽  
Vol 2016 ◽  
pp. 1-6 ◽  
Author(s):  
Ricardo Rocha Bastos ◽  
Carla Sofia Ferreira ◽  
Elisete Brandão ◽  
Fernando Falcão-Reis ◽  
Ângela M. Carneiro
Keyword(s):  
Image Analysis ◽  
Multimodal Imaging ◽  
Age Of Onset ◽  
Fundus Autofluorescence ◽  
Correct Diagnosis ◽  
Retinal Diseases ◽  
Adult Onset ◽  
Fundus Photographs ◽  
Sd Oct

Purpose. To characterize vitelliform lesions (VLs) in adult-onset foveomacular vitelliform dystrophy (AOFVD) and acquired vitelliform (AVL) patients using multimodal image analysis.Methods. Retrospective study of twenty-eight eyes from nineteen patients diagnosed with AVL or AOFVD. They were evaluated by color fundus photographs, fundus autofluorescence (FAF), fluorescein angiography (FA), and spectral-domain optical coherence tomography (SD-OCT).Results. Bilateral VLs were associated with AOFVD(p=0.013). Regular and centered VLs were associated with AOFVD (p=0.004andp=0.016), whereas irregular and noncentered lesions were more frequent in AVL patients. Visual acuity, greatest linear dimension (GLD), lesion height (LH), and pseudohypopyon were similar between groups. Whereas median LH and GLD in AVL group diminished significantly during follow-up (p=0.009andp=0.001), AOFVD lesions tended to become larger and thicker.Conclusions. When consulting a patient presenting a VL with unknown age of onset, familial history, or previous retinal diseases, some aspects of multimodal imaging assessment may lead the ophthalmologist to a correct diagnosis.

scholarly journals Microsurgical resection of previously embolized recurrent cerebellopontine angle AVM

2021 ◽  
Vol 4 (1) ◽  
pp. V2
Author(s):  
Ehsan Dowlati ◽  
Kelsi Chesney ◽  
Vikram V. Nayar
Keyword(s):  
Arteriovenous Malformation ◽  
Indocyanine Green ◽  
Endovascular Treatment ◽  
Cerebellopontine Angle ◽  
Indocyanine Green Angiography ◽  
Transverse Sinus ◽  
Grade Ii ◽  
Microsurgical Resection ◽  
Martin Grade

This is the case of a ruptured Spetzler-Martin grade II arteriovenous malformation (AVM) located in the cerebellopontine angle and draining into the transverse sinus. The AVM was initially treated with staged embolization using Onyx (ev3 Neurovascular). However, recurrence was noted and treatment with microsurgical resection was undertaken. The authors present technical nuances of the approach and strategies for microsurgical resection of a previously embolized recurrent AVM with the aid of intraoperative indocyanine green angiography. Follow-up after endovascular treatment is critical, and curative treatment with microsurgical resection can be achieved with low morbidity in such AVMs as demonstrated by this case.The video can be found here: https://youtu.be/LMpz_YTFC0g

scholarly journals The Evaluatıon of The Effıcacy of Adalımumab in Refractory Non-Infectıous Uveıtıs Wıth Ultra-Wıdefıeld Fundus Fluoresceın Angıography

2021 ◽  
Author(s):  
Dilek UZLU ◽  
Büşra Köse ◽  
Nurettin Akyol ◽  
Hidayet Erdöl ◽  
Murat Günay
Keyword(s):  
Fluorescein Angiography ◽  
Choroidal Thickness ◽  
Vascular Leakage ◽  
Fundus Fluorescein Angiography ◽  
Study Results ◽  
Infectious Uveitis ◽  
The Mean ◽  
Active Inflammation

Abstract Aim: To investigate the efficacy of adalimumab in the cases with refractory non-infectious uveitis and evaluate retinal vascular leakage changes on ultra-widefield fundus fluorescein angiography.Methods: Twenty-three patients with refractory uveitis were included in study. Results: Forty-four eyes of 23 patients with non-infectious uveitiswere evaluated. Clinically active inflammation was present in 19 eyes (43.18%), while 25 (56.8%) were inactive. The mean drug burden was a 9.91±3.78 (5-21) in baseline, 7.3±4.25 at third and 8.0±4.71 at sixth month (p=0.022). The mean choroidal thickness was 256.65±43.63 μm in baseline, 240.49±36.73 μm at third and 224.81±34.91 μm at sixth month (p≤0.05). In terms of leakage extend, leakage was initially present in a mean of 2.95±4.55 clock hour quadrants, 2.41±3.91 at thirdand 1.76±3.44 at sixth month (p<0.001). Conclusion: Adalimumab was found to be effective in establishing inflammation control by reducing drug burden, controlling retinal vascular leakage and choroidal inflammation in refractory uveitis.

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