Effects of Chinese herbal medicine Bushen Gubiao Recipe on toll-like receptor 4 and CD4+CD25+foxp3+ regulatory T cells in mice with recurrent respiratory tract infections

2010 ◽  
Vol 8 (11) ◽  
pp. 1053-1059 ◽  
Author(s):  
YB Zhou
Keyword(s):  
T Cells ◽  
Herbal Medicine ◽  
Respiratory Tract ◽  
Chinese Herbal Medicine ◽  
Respiratory Tract Infections ◽  
Toll Like Receptor ◽  
Toll Like Receptor 4 ◽  
Chinese Herbal ◽  
Tract Infections ◽  
Recurrent Respiratory Tract Infections

scholarly journals Retraction Note: Childhood iron deficiency anemia leads to recurrent respiratory tract infections and gastroenteritis

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Jayaweera Arachchige Asela Sampath Jayaweera ◽  
Mohammed Reyes ◽  
Anpalaham Joseph
Keyword(s):  
Iron Deficiency ◽  
Respiratory Tract ◽  
Iron Deficiency Anemia ◽  
Respiratory Tract Infections ◽  
Deficiency Anemia ◽  
Link Type ◽  
Tract Infections ◽  
Recurrent Respiratory Tract Infections

Editor's Note: this Article has been retracted; the Retraction Note is available at https://doi.org/10.1038/s41598-021-90018-8.

scholarly journals Acceptability of a Sublingual Drug Formulation for Respiratory Tract Infections in Children Aged 3 to 5 Years

Pharmaceutics ◽  
2021 ◽  
Vol 13 (2) ◽  
pp. 294
Author(s):  
Andrzej Emeryk ◽  
Thibault Vallet ◽  
Ewelina Wawryk-Gawda ◽  
Arkadiusz Jędrzejewski ◽  
Frederic Durmont ◽  
...  
Keyword(s):  
Respiratory Tract ◽  
Respiratory Tract Infections ◽  
Drug Formulation ◽  
Reference Framework ◽  
Significant Difference ◽  
Key Factor ◽  
Treatment Safety ◽  
The Many ◽  
Tract Infections ◽  
Recurrent Respiratory Tract Infections

In pediatrics, acceptability has emerged as a key factor for compliance, and consequently for treatment safety and efficacy. Polyvalent mechanical bacterial lysate (PMBL) in 50-mg sublingual tablets is indicated in children and adults for the prophylaxis of recurrent respiratory tract infections. This medication may be prescribed in children over 3 years of age; the appropriateness of this sublingual formulation should thus be demonstrated amongst young children. Using a multivariate approach integrating the many aspects of acceptability, standardized observer reports were collected for medication intake over the course of treatment (days 1, 2, and 10) in 37 patients aged 3 to 5 years, and then analyzed in an intelligible model: the acceptability reference framework. According to this multidimensional model, 50-mg PMBL sublingual tablets were classified as “positively accepted” in children aged 3 to 5 years on all three days of evaluation. As the acceptability evaluation should be relative, we demonstrated that there was no significant difference between the acceptability of these sublingual tablets and a score reflecting the average acceptability of oral/buccal medicines in preschoolers. These results highlight that sublingual formulations could be appropriate for use in preschoolers.

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