scholarly journals Chinese Herbal Medicine in the Treatment of Acute Respiratory Tract Infections: Review of Randomized and Controlled Clinical Trials

1999 ◽  
Vol 28 (2) ◽  
pp. 235-236 ◽  
Author(s):  
Chaoying Liu ◽  
Robert M. Douglas
Keyword(s):  
Clinical Trials ◽  
Herbal Medicine ◽  
Respiratory Tract ◽  
Chinese Herbal Medicine ◽  
Respiratory Tract Infections ◽  
Controlled Clinical Trials ◽  
Acute Respiratory Tract Infections ◽  
Chinese Herbal ◽  
Tract Infections

scholarly journals Use of OM-85 BV for the Prevention of Acute Respiratory Tract Infections in Occupational Medicine

2002 ◽  
Vol 30 (3) ◽  
pp. 325-329 ◽  
Author(s):  
MA Carmona-Ramírez ◽  
V Alvárez-Gómez ◽  
A Berber
Keyword(s):  
Respiratory Tract ◽  
Occupational Medicine ◽  
Respiratory Tract Infections ◽  
Controlled Clinical Trials ◽  
Factory Workers ◽  
Double Blind ◽  
Double Blind Placebo ◽  
Acute Respiratory Tract Infections ◽  
Job Roles ◽  
Tract Infections

This study evaluated the safety and efficacy of the immunostimulatory agent OM-85 BV in 112 male car-factory workers who were highly susceptible to acute respiratory tract infections (ARTIs), each having experienced ≥ 4 ARTIs during 1999. From January to March 2000, each worker received one capsule of OM-85 BV (7 mg) per day for 10 consecutive days each month. The patients were followed for a further 9 months. Mean number of ARTIs decreased from 8.2 ± 2.1 per worker in 1999 to 5.3 ± 2.9 in 2000; i.e. a difference of −2.9 (95% confidence intervals, −3.5 to −2.4). Similar effects were observed in men who had different job roles, and no adverse events were reported during drug administration. We concluded that OM-85 BV appears to be safe and effective in reducing the incidence of ARTIs in susceptible workers, although further double-blind, placebo-controlled clinical trials are required.

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