scholarly journals Chinese herbal medicine for acute upper respiratory tract infections and reproductive safety: A systematic review

2019 ◽  
Vol 13 (2) ◽  
pp. 117-129 ◽  
Author(s):  
Zengshu Huang ◽  
Xinyao Pan ◽  
Jing Zhou ◽  
Wing Ting Leung ◽  
Chuyu Li ◽  
...  
Keyword(s):  
Systematic Review ◽  
Herbal Medicine ◽  
Respiratory Tract ◽  
Chinese Herbal Medicine ◽  
Respiratory Tract Infections ◽  
Upper Respiratory Tract Infections ◽  
Upper Respiratory Tract ◽  
Chinese Herbal ◽  
Upper Respiratory ◽  
Tract Infections

scholarly journals Probiotics for the Prevention of Acute Respiratory-Tract Infections in Older People: Systematic Review

Healthcare ◽  
2021 ◽  
Vol 9 (6) ◽  
pp. 690
Author(s):  
Maja Strauss ◽  
Dušanka Mičetić-Turk ◽  
Maja Šikić Pogačar ◽  
Sabina Fijan
Keyword(s):  
Systematic Review ◽  
Respiratory Tract ◽  
Older People ◽  
Respiratory Tract Infections ◽  
Current Evidence ◽  
Upper Respiratory Tract Infections ◽  
Upper Respiratory Tract ◽  
Probiotic Strains ◽  
Upper Respiratory ◽  
Tract Infections

The aim of this systematic review was to present the indirect influence of probiotics on the incidence and duration of acute upper respiratory-tract infections in older people, by regulating the immune system. Eight randomized, placebo-controlled clinical trials met the inclusion criteria, considering the threshold of older people being 60 years and over. Single strain probiotics were used in all studies, including three probiotic strains used in fermented foods: Lactobacillus delbrueckii subsp. bulgaricus OLL1073R-1, Lacticaseibacillus paracasei subsp. paracasei CNCM I-1518 and Lacticaseibacillusparacasei Shirota, and three probiotic strains used as food supplements: Loigolactobacillus coryniformis K8 CECT5711, Bacillus subtilis CU1 and Lacticaseibacillus rhamnosus GG. Current evidence showed that certain probiotic strains were better than a placebo in lowering the incidence or number of older people experiencing acute upper respiratory tract infections; however, not all probiotic strains were efficient, and not all studies reported statistically significant outcomes. More high quality large-scale properly controlled clinical studies focusing on older people are warranted.

scholarly journals Effectiveness of honey for symptomatic relief in upper respiratory tract infections: a systematic review and meta-analysis

2020 ◽  
pp. bmjebm-2020-111336 ◽  
Author(s):  
Hibatullah Abuelgasim ◽  
Charlotte Albury ◽  
Joseph Lee
Keyword(s):  
Systematic Review ◽  
Antimicrobial Resistance ◽  
Respiratory Tract ◽  
Respiratory Tract Infections ◽  
Meta Analysis ◽  
Symptomatic Relief ◽  
Upper Respiratory Tract Infections ◽  
Upper Respiratory Tract ◽  
Upper Respiratory ◽  
Tract Infections

BackgroundAntibiotic over prescription for upper respiratory tract infections (URTIs) in primary care exacerbates antimicrobial resistance. There is a need for effective alternatives to antibiotic prescribing. Honey is a lay remedy for URTIs, and has an emerging evidence base for its use. Honey has antimicrobial properties, and guidelines recommended honey for acute cough in children.ObjectivesTo evaluate the effectiveness of honey for symptomatic relief in URTIs.MethodsA systematic review and meta-analysis. We searched Pubmed, Embase, Web of Science, AMED, Cab abstracts, Cochrane Library, LILACS, and CINAHL with a combination of keywords and MeSH terms.ResultsWe identified 1345 unique records, and 14 studies were included. Overall risk of bias was moderate. Compared with usual care, honey improved combined symptom score (three studies, mean difference −3.96, 95% CI −5.42 to −2.51, I2=0%), cough frequency (eight studies, standardised mean difference (SMD) −0.36, 95% CI −0.50 to −0.21, I2=0%) and cough severity (five studies, SMD −0.44, 95% CI −0.64 to −0.25, I2=20%). We combined two studies comparing honey with placebo for relieving combined symptoms (SMD −0.63, 95% CI −1.44 to 0.18, I2=91%).ConclusionsHoney was superior to usual care for the improvement of symptoms of upper respiratory tract infections. It provides a widely available and cheap alternative to antibiotics. Honey could help efforts to slow the spread of antimicrobial resistance, but further high quality, placebo controlled trials are needed.PROSPERO registration NoStudy ID, CRD42017067582 on PROSPERO: International prospective register of systematic reviews (https://www.crd.york.ac.uk/prospero/).

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