scholarly journals DIET THERAPY IN CHILDREN WITH FOOD ALLERGY

2013 ◽  
Vol 10 (5) ◽  
pp. 70-75
Author(s):  
E E Varlamov ◽  
A N Pampura
Keyword(s):  
Atopic Dermatitis ◽  
Food Allergy ◽  
Amino Acid ◽  
Diet Therapy ◽  
Average Value ◽  
Multiple Food Allergy ◽  
Amino Acid Formula

Introduction. Experience of amino acid formulas application in eldest children is limited. Background. To estimate efficiency of amino acid formula at children at the age from 1 till 10 years with atopic dermatitis (AD). Methods. 9 AD children with multiple food allergy were included in the study. All patients took amino acid formula «Neocate Advance». The efficiency of diet therapy was estimated with index SCORAD. Results. The average value of index SCORAD decreased AFTER 1 week therapy, Me — 48,5 [44,5; 52,5] to Me — 18,8 [18; 37,5] a point (p=0,008), after 2 weeks — Me — 12,6 [7,8; 13,5] a point (p=0,008). Conclusion. Medical amino acid formula «Neocate Advance» is an effective diet therapy of AD children with multiple food allergy.

scholarly journals FEATURES OF DIET THERAPY IN INFANTS WITH POLYVALENTFOOD ALLERGY

2010 ◽  
Vol 7 (6) ◽  
pp. 60-63
Author(s):  
A N Pampura ◽  
E E Varlamov
Keyword(s):  
Atopic Dermatitis ◽  
Food Allergy ◽  
Amino Acid ◽  
Challenge Test ◽  
Specific Ige ◽  
Elimination Diet ◽  
Food Protein ◽  
Oral Challenge Test ◽  
Protein Intolerance ◽  
Amino Acid Formula

Background. Establish indications for prescription of amino acid formula to infants with atopic dermatitis. Methods. 55 infants with atopic dermatitis and food allergy were enrolled. Allergic examination included skin prick tests and evaluation of specific IgE level. Oral challenge test was performed if necessary. Results. Low efficacy of elimination diet was observed in 16 infants with multiple food protein intolerance. In the issue cluster analysis defined two subgroups. High IgE levels, specific IgE to egg and fish were considered as criterions of the first subgroup. Patients with multiple food protein intolerance and low efficacy to elimination diet received amino acid formula, SCORAD index decreased more than 50% after the first week of treatment. Conclusion. Multiple food protein intolerance is particular form of food allergy. Prescription of amino acid formula is reasonable in this category of patients.

scholarly journals Clinical and immunological characteristics ofpatients with polyvalent food allergy in reasoning of clinical prescribing of amino acid formula

2012 ◽  
Vol 9 (1) ◽  
pp. 84-87
Author(s):  
E E Varlamov ◽  
T S Okuneva ◽  
A N Pampura
Keyword(s):  
Atopic Dermatitis ◽  
Food Allergy ◽  
Amino Acid ◽  
Fruits And Vegetables ◽  
Specific Ige ◽  
Food Intolerance ◽  
Cow Milk ◽  
Amino Acid Formula

Methods: 117 infants with atopic dermatitis and food allergy were enrolled. The analysis of clinical and immunological characteristics of the infants with multiple food intolerance was performed. Results: asthma, high levels of specific IgE to cow milk, egg, beef, pork, sensitization to allergens of cereals, fruits and vegetables were characterized for infants with multiple food intolerance. Conclusion: infants with multiple food intolerance possess defined clinical and immunological characteristics which can form the basis for prescribing of amino acid formula.

scholarly journals The efficiency of diet therapy based on amino-acid formula «Neocate Advance»® in treatment of children with severe atopic dermatitis and cow’s milk food allergy. Clinical cases

2016 ◽  
Vol 13 (1) ◽  
pp. 27-37
Author(s):  
O G Elisutina ◽  
O K Shtyrbul ◽  
A N Pampura ◽  
O A Erina ◽  
E S Fedenko
Keyword(s):  
Atopic Dermatitis ◽  
Food Allergy ◽  
Amino Acid ◽  
Correct Choice ◽  
Diet Therapy ◽  
Cow’S Milk ◽  
Severe Atopic Dermatitis ◽  
Cow's Milk ◽  
Abnormal Immune Response ◽  
Ige Mediated

A food allergy is an abnormal immune response to food, mostly depended on IgE-mediated reactions. One of the most common symptoms of children’s food allergy is atopic dermatitis. The primary goal of diet therapy is the correct choice of hypoallergenic formula. In this article the cases of using amino-acid based formula «Neocate Advance»® in treatment of children with severe atopic dermatitis and cow’s milk food allergy are considered.

scholarly journals FEATURES OF THE CYTOKINE PROFILE IN INFANTS WITH MULTIPLE FOOD PROTEIN INTOLERANCE

2012 ◽  
Vol 9 (5) ◽  
pp. 76-80
Author(s):  
E E Varlamov ◽  
T V Vinogradova ◽  
A A Chuslyaeva ◽  
A N Pampura
Keyword(s):  
Atopic Dermatitis ◽  
Food Allergy ◽  
Amino Acid ◽  
Inflammatory Process ◽  
Allergic Diseases ◽  
Cytokine Profile ◽  
Food Protein ◽  
Additional Indication ◽  
Protein Intolerance

Introduction. Types of the course of allergic diseases may be related to cytokine profile. Determination of the spectrum of cytokines to evaluate the mechanisms of allergic inflammatory process that improves the efficiency of management of patients with allergic diseases was performed. Background. To establish the features of cytokine profile in children with multiple food protein intolerance. Methods. 39 children with atopic dermatitis and food allergy were included in the openlabel study, 18 of whom had multiple food protein intolerance. All patients were examined with enzyme immunoassay (ELISA) to determine the concentration of IL-4, IL-5, IL-13, IL-17, IL-22, eotaxin, eotaxin2, TGF-β. Results. In children with multiple food protein intolerance the concentration of TGF-β was increased in comparison with the group of children without multiple food intolerances Me 14,04 [11,3; 18,0] against 10,3 [4,8; 12, 8] pg/ml, respectively, p = 0,038. The level of other cytokines had no difference. Conclusion. Increased concentration of TGF-β in patients with multiple food protein intolerance may be an additional indication for the amino acid formulas.

Clinical effectiveness of amino acid formula in infants with severe atopic dermatitis and cow's-milk protein allergy

2016 ◽  
Vol 91 (6) ◽  
pp. 521-527
Author(s):  
Serhiy Nyankovskyy ◽  
Olena Nyankovska ◽  
Dmytro Dobryanskyy ◽  
Oleg Shadrin ◽  
Viktoria Klimenko ◽  
...  
Keyword(s):  
Atopic Dermatitis ◽  
Amino Acid ◽  
Milk Protein ◽  
Clinical Effectiveness ◽  
Cow’S Milk ◽  
Severe Atopic Dermatitis ◽  
Cow's Milk ◽  
Cow’S Milk Protein ◽  
Amino Acid Formula

scholarly journals The estimation of efficiency of diet therapy in atopic dermatitis and food allergy in children

2012 ◽  
Vol 9 (4) ◽  
pp. 72-78
Author(s):  
V A Revyakina ◽  
K G Sharapova ◽  
E YU Berezina ◽  
T B Sentsova ◽  
O YU Monosova ◽  
...  
Keyword(s):  
Atopic Dermatitis ◽  
Food Allergy ◽  
Milk Protein ◽  
Goat Milk ◽  
Serum Levels ◽  
Diet Therapy ◽  
Cow Milk ◽  
Milk Formula ◽  
Igg Antibodies ◽  
Positive Skin

Background. Clinical and immunological estimation of efficiency of different special formulas in children with atopic dermatitis due to food allergy. Methods. Fifty four children with atopic dermatitis aged 0,5—3 years old were examined. Children were divided into three groups on the base of their diet therapy. The 1 st group included 15 patients on the hypoallergenic milk-free diet, the 2 nd group (18 patients) was fed by goat milk formula, and the 3 rd group (21 children) was fed by special formula with high hydrolyzed protein. The dynamics of serum levels of IgE and IgG antibodies to cow milk protein and its fractions, and dynamics of cytokine levels (IL-4, IL-5, and IL-10) were measured during different types of diet therapy. Results. The positive skin changes during diet therapy included decrease of erythema, exudation and itching, gradual regression of rash. In 3 months of therapy complete clinical remission was achieved in 10 (66,7%) children in the 1 st group, in 14 (77,8%) children in the 2 nd group and in 15 (71,7%) children in the 3 rd group. The significant decrease of levels of IgG antibodies levels to cow milk protein and its fractions in children during different elimination diets was determined. The significant decrease of levels of specific IgE antibodies to cow milk protein (p

scholarly journals A Combined Analysis of Gut and Skin Microbiota in Infants with Food Allergy and Atopic Dermatitis: A Pilot Study

Nutrients ◽  
2021 ◽  
Vol 13 (5) ◽  
pp. 1682
Author(s):  
Ewa Łoś-Rycharska ◽  
Marcin Gołębiewski ◽  
Marcin Sikora ◽  
Tomasz Grzybowski ◽  
Marta Gorzkiewicz ◽  
...  
Keyword(s):  
Atopic Dermatitis ◽  
Food Allergy ◽  
Gut Microbiota ◽  
Bacterial Species ◽  
Rrna Gene ◽  
Healthy Children ◽  
Skin Microbiota ◽  
Fecal Samples ◽  
Healthy Infants ◽  
Α Diversity

The gut microbiota in patients with food allergy, and the skin microbiota in atopic dermatitis patients differ from those of healthy people. We hypothesize that relationships may exist between gut and skin microbiota in patients with allergies. The aim of this study was to determine the possible relationship between gut and skin microbiota in patients with allergies, hence simultaneous analysis of the two compartments of microbiota was performed in infants with and without allergic symptoms. Fifty-nine infants with food allergy and/or atopic dermatitis and 28 healthy children were enrolled in the study. The skin and gut microbiota were evaluated using 16S rRNA gene amplicon sequencing. No significant differences in the α-diversity of dermal or fecal microbiota were observed between allergic and non-allergic infants; however, a significant relationship was found between bacterial community structure and allergy phenotypes, especially in the fecal samples. Certain clinical conditions were associated with characteristic bacterial taxa in the skin and gut microbiota. Positive correlations were found between skin and fecal samples in the abundance of Gemella among allergic infants, and Lactobacillus and Bacteroides among healthy infants. Although infants with allergies and healthy infants demonstrate microbiota with similar α-diversity, some differences in β-diversity and bacterial species abundance can be seen, which may depend on the phenotype of the allergy. For some organisms, their abundance in skin and feces samples may be correlated, and these correlations might serve as indicators of the host’s allergic state.

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