scholarly journals Peculiarities of non-allergic rhinitis with eosinophilia syndrome

2015 ◽  
Vol 12 (4) ◽  
pp. 3-7
Author(s):  
V A Utesheva ◽  
G P Bondareva ◽  
A I Kryukov ◽  
T G Barkhina

Nonallergic rhinitis with eosinophilia syndrome (NARES) is a syndrome containing the symptoms similar to allergic rhinitis, with absence of atopy and the presence of eosinophila more than 20% in smears from nasal mucosa. Pathophysiology of NARES has not been studied completely, but permanent eosinophilic inflammation is the keystone of NARES pathogenesis. This disease is marked by local eosinophilic infiltration without atopy, confirmed by negative skin tests, normal levels of total and specific IgE in serum, negative nasal provocation tests with allergens. Nowadays this nosology is considered to be poorly understood.

2019 ◽  
Vol 30 (3) ◽  
pp. 296-304 ◽  
Author(s):  
Olympia Tsilochristou ◽  
Marialena Kyriakakou ◽  
Ioanna Manolaraki ◽  
John Lakoumentas ◽  
Ekaterini Tiligada ◽  
...  

2015 ◽  
Vol 273 (6) ◽  
pp. 1469-1475 ◽  
Author(s):  
Sven Becker ◽  
Julia Rasp ◽  
Katharina Eder ◽  
Alexander Berghaus ◽  
Matthias F. Kramer ◽  
...  

ORL ◽  
2021 ◽  
pp. 1-6
Author(s):  
Giancarlo Pecorari ◽  
Giuseppe Riva ◽  
Claudia Bartoli ◽  
Mattia Ravera ◽  
Valeria Dell’Era ◽  
...  

Introduction: Radiofrequency turbinate volume reduction (RFTVR) is an effective treatment of inferior turbinate hypertrophy. RFTVR can reduce epithelial cell alterations in nasal mucosa. The aim of this observational study was to evaluate the effects of RFTVR on nasal obstruction and cytology, stratifying for different types of rhinitis. Methods: Nasal cytology and subjective nasal obstruction were evaluated on 113 patients before RFTVR (T0) and after 3 months (T1). The patients were divided into groups on the basis of the underlying disease: allergic rhinitis, nonallergic rhinitis, rhinitis medicamentosa, and other diseases (e.g., hormonal-based turbinate hypertrophy). Results: Nasal cytology at T0 identified 42 patients with allergic rhinitis, 40 with nonallergic rhinitis, 19 with rhinitis medicamentosa, and 12 with other diseases. An improvement of nasal cytology at T1 was observed in 29.2% of cases. They mainly consisted of patients with nonallergic rhinitis with neutrophils, whose neutrophil infiltrate decreased. Only 2 cases (1.7%) showed a worsening of nasal cytology at T1. A statistically significant decrease in subjective nasal obstruction was observed for every group (p < 0.05). Higher differences of nasal obstruction between T0 and T1 were found in patients with rhinitis medicamentosa or other diseases. Conclusion: RFTVR represents a safe and effective treatment for turbinate hypertrophy of various etiology. It is not responsible for a worsening of inflammatory infiltrate of the nasal mucosa.


2014 ◽  
Vol 67 (suppl. 1) ◽  
pp. 49-56
Author(s):  
Maja Buljcik-Cupic ◽  
Dragana Lemez ◽  
Slobodan Savovic ◽  
Ljiljana Jovancevic ◽  
Danijela Dragicevic

Local allergic rhinitis is a localized allergic response of the nasal mucosa to aeroallergens in the absence of atopy with characteristic production of specific local immunoglobulin E antibodies in the nasal mucosa, T helper type 2 cellular infiltration response during the exposure to aeroallergens and positive results via the nasal allergic provocation test with the release of inflammatory mediators (triptase and eosinophil cationic proteins). Even though the prevalence of local allergic rhinitis has been and is still being investigated, a large number of patients with diagnosed non-allergic rhinitis or idiopathic rhinitis are currently classified as having local allergic rhinitis. The causes of local allergic rhinitis are most commonly house dust, dust mites, pollens and many others. Diagnosis of local allergic rhinitis is made using nasal allergen provocation tests when the prick test for standard inhalation allergens and the serum specific immunoglobulin analysis for aeroallergens are negative. The increasing amount of data on localized allergic response in non-atopic patients asks for many answers regarding local allergic rhinitis. These answers can be obtained by a study on the prevalence and incidence in children and adults, the impact of positive family atopy in the development of disease, the impact of associated diseases of the lower respiratory tract and conjunctiva, the effectiveness of drug treatment and the issue of administration of specific immunotherapy.


2002 ◽  
Vol 109 (1) ◽  
pp. S98-S98
Author(s):  
Alan Wolff ◽  
Kumar Patel ◽  
John Oppenheimer ◽  
Stan H Weiss ◽  
Leonard Bielory

1986 ◽  
Vol 18 (1-2) ◽  
pp. 251-253 ◽  
Author(s):  
Emanuela Masini ◽  
L. Rucci ◽  
Maria Bruna Cirri-Borghi ◽  
Eliana Giannella ◽  
P. F. Mannaioni

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