scholarly journals Paradoxical side effect in treatment with antipsychotics for aggression/agitation and psychosis in dementia: case-series

2020 ◽  
Vol 85 (2) ◽  
pp. 119-126
Author(s):  
Tudor Florea ◽  
Matei Palimariciuc ◽  
Vasile Chiriță ◽  
Roxana Chiriță
Keyword(s):  
Side Effect ◽  
Case Series ◽  
Dementia Case

scholarly journals Drug Induced Encephalopathy in Patients with Chronic Kidney Disease: A Case Series

2018 ◽  
Vol 8 (2) ◽  
pp. 172-176
Author(s):  
Wasim Md Mohosin Ul Haque ◽  
Tabassum Samad ◽  
Muhammad Abdur Rahim ◽  
Shudhanshu Kumar Saha ◽  
Sarwar Iqbal
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Renal Impairment ◽  
Side Effect ◽  
Case Series ◽  
Special Group ◽  
Drug Induced ◽  
Reduced Dose

Drug induced encephalopathy is an established side effect of many drugs when used in a higher dose. Though we do not encounter this side effect frequently in our day to day practice, yet with renal impairment this is not uncommon. Even with a reduced dose many of these can precipitate encephalopathy in this special group of patients. We are presenting here a series of seven such cases of drug induced encephalopathy in patients with renal impairment.Birdem Med J 2018; 8(2): 172-176

scholarly journals Efavirenz induced gynecomastia, hidden reality: a case series

2020 ◽  
Vol 7 (11) ◽  
pp. 1747
Author(s):  
Dnyanesh N. Morkar ◽  
Ankita Aneja ◽  
Rishabh Agarwal
Keyword(s):  
Side Effects ◽  
Hiv Infection ◽  
Side Effect ◽  
Case Series ◽  
Drug Adherence ◽  
Resource Limited Settings ◽  
Hiv Patients ◽  
Highly Active ◽  
Resource Limited ◽  
Haart Therapy

The prognosis of HIV infection has considerably improved following the introduction of highly active anti-retroviral therapy by reducing AIDS related morbidity and mortality. At the same time, ART drugs are well known for their side effects. Gynaecomastia is a lesser known side effect of a commonly used anti-retroviral drug efavirenz. There are very few reports of HAART-induced gynaecomastia in resource-limited settings. The current study presents a series of three cases that developed ultrasound confirmed gynaecomastia following efavirenz containing HAART. Initial reports of gynaecomastia related to HAART were in HIV patients with lipodystrophy, they were termed as pseudogynaecomastia. Gradually, few reports of efavirenz related gynaecomastia were published wherein other causes of gynaecomastia were ruled out. Several hypothesis have been suggested for the pathophysiology of development of gynaecomastia related to efavirenz consumption. All other causes were ruled out in our patients too. The incidence of gynaecomastia is increasing in men with HIV on HAART therapy, proper identification and management will promote better drug adherence.

Intracranial Dural Arteriovenous Fistula as a Reversible Cause of Dementia: Case Series and Literature Review

2019 ◽  
Vol 121 ◽  
pp. e543-e553 ◽  
Author(s):  
Arnaldo Brito ◽  
Anderson Chun On Tsang ◽  
Christopher Hilditch ◽  
Patrick Nicholson ◽  
Timo Krings ◽  
...  
Keyword(s):  
Literature Review ◽  
Arteriovenous Fistula ◽  
Dural Arteriovenous Fistula ◽  
Case Series ◽  
Dementia Case

scholarly journals Donepezil for Compulsive Behavior in Degenerative Dementia: Case Series

2018 ◽  
Vol 16 (2) ◽  
pp. 224-227
Author(s):  
Biswa Ranjan Mishra ◽  
Vanteemar S. Sreeraj ◽  
Saranya Dhanashekaran ◽  
Rituparna Maiti
Keyword(s):  
Case Series ◽  
Compulsive Behavior ◽  
Dementia Case ◽  
Degenerative Dementia

scholarly journals A case series of efavirenz induced gynaecomastia

2021 ◽  
Vol 8 (7) ◽  
pp. 984
Author(s):  
Balakrishna Teli ◽  
Sneha Biradar ◽  
Sheshan V. S.
Keyword(s):  
Side Effects ◽  
Hiv Infection ◽  
Side Effect ◽  
Case Reports ◽  
Case Series ◽  
Drug Adherence ◽  
Resource Limited Settings ◽  
Highly Active ◽  
Resource Limited ◽  
Haart Therapy

The prognosis of HIV infection has significantly changed following the introduction of highly active anti-retroviral therapy by reducing AIDS related morbidity and mortality. At the same time, HAART is documented for its side effects. Gynaecomastia is a less documented side effect of a commonly used ART drug efavirenz. There are only few case reports of HAART-induced gynaecomastia in resource limited settings. Initially gynaecomastia related to HAART in HIV patients was thought due to lipodystrophy and was termed as pseudogynaecomastia. Later, few case reports of efavirenz related gynaecomastia were published after ruling out other causes of gynaecomastia. All other causes of gynaecomastia were ruled out in our patients too. The incidence of gynaecomastia is increasing in men with HIV on HAART therapy, proper identification and management will promote better drug adherence. The present study presented a series of two cases that developed ultrasound confirmed gynaecomastia following efavirenz containing HAART.

scholarly journals A Case Series of Severe Hyperammonemia Encephalopathy Related to Valproate: Can Antipsychotics Increase the Risk?

2019 ◽  
Author(s):  
Effat Davoudi-Monfared ◽  
Mojan Radmehr ◽  
Padideh Ghaeli ◽  
Maryam Mousavi
Keyword(s):  
Risk Factors ◽  
Risk Factor ◽  
Psychiatric Disorder ◽  
Side Effect ◽  
Case Series ◽  
Nutritional Deficiencies ◽  
Common Side Effect ◽  
Hyperammonemic Encephalopathy

Valproate-induced hyperammonemia is a common side effect of valproate, which may occur either without any symptoms or may rarely cause symptoms of encephalopathy. Different risk factors have been defined for this side effect, including some nutritional deficiencies and polypharmacy (eg, other anticonvulsants). Three cases with psychiatric disorder who showed symptoms of severe hyperammonemia encephalopathy and had taken valproate with antipsychotics, especially risperidone, are presented here. In all cases, the symptoms were improved by discontinuation of valproate. Administration of antipsychotic may be considered as a risk factor for hyperammonemic encephalopathy related to valproate, specifically in some prone populations.

Cefotetan-Induced Hemolytic Anemia: Case Series and Review

2018 ◽  
Vol 32 (6) ◽  
pp. 679-682 ◽  
Author(s):  
Kathlyn Lim ◽  
Hai Tran ◽  
Angela Hirai-Yang ◽  
Niyati Vakil ◽  
Gregory Marks ◽  
...  
Keyword(s):  
Hemolytic Anemia ◽  
Side Effect ◽  
Medical Center ◽  
Case Series ◽  
Antibody Testing ◽  
Drug Induced ◽  
Immune Hemolytic Anemia

Purpose: To raise awareness of cefotetan-induced hemolytic anemia, a known rare but serious side effect that occurred in 5 patients at our medical center. Summary: Five cases of cefotetan-induced hemolytic anemia, which presented over the period of a single year at our center, are described. In each case, hemolytic anemia was confirmed by testing for the presence of anti-cefotetan antibodies. Each case occurred approximately 1 to 2 weeks following exposure to the drug. All five patients survived. A brief review of drug-induced immune hemolytic anemia (DIIHA) is also discussed. Conclusion: DIIHA may be difficult to distinguish from other causes of hemolytic anemia, but should be included in the differential in patients exposed to medications associated with DIIHA. Once suspected, antibody testing should be performed, and once diagnosed, further exposure should be avoided.

scholarly journals Successful treatment of severe psoriasis vulgaris in child with methotrexate injection

2019 ◽  
Author(s):  
Agatha Anindhita ◽  
S. Sawitri
Keyword(s):  
Side Effect ◽  
Psoriasis Vulgaris ◽  
Systemic Treatment ◽  
Case Series ◽  
Severe Psoriasis ◽  
Expert Opinions ◽  
Mild Improvement ◽  
Pasi Score ◽  
History Of ◽  
Pediatric Disorders

Pediatric psoriasis could begin in childhood in almost one-third of the cases. There are currently no international standardized guidelines for medical treatment of pediatric psoriasis. Case: A 3-years-old girl with a 1-year history of psoriasis came to outpatient clinic. She already went to dermatologist but only reached mild improvement. The lesion became worse within 2 months. PASI score was 32. The patient was given methotrexate injection 0,5 mg/BW/week for about 3 months. PASI score was decrease and became 15 after 3 months of the therapy with no serious side effect. Discussion: The treatment approach is based primarily on guidelines for adult psoriasis, a few case series, expert opinions, or experience with systemic drugs acquired in other pediatric disorders. Systemic treatment was given to this patient because the child was categorized as severe psoriasis. Conclusion: Methotrexate treatment in this patient was showed a good progression with no serious side effect.

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