Cefotetan-Induced Hemolytic Anemia: Case Series and Review

2018 ◽  
Vol 32 (6) ◽  
pp. 679-682 ◽  
Author(s):  
Kathlyn Lim ◽  
Hai Tran ◽  
Angela Hirai-Yang ◽  
Niyati Vakil ◽  
Gregory Marks ◽  
...  
Keyword(s):  
Hemolytic Anemia ◽  
Side Effect ◽  
Medical Center ◽  
Case Series ◽  
Antibody Testing ◽  
Drug Induced ◽  
Immune Hemolytic Anemia

Purpose: To raise awareness of cefotetan-induced hemolytic anemia, a known rare but serious side effect that occurred in 5 patients at our medical center. Summary: Five cases of cefotetan-induced hemolytic anemia, which presented over the period of a single year at our center, are described. In each case, hemolytic anemia was confirmed by testing for the presence of anti-cefotetan antibodies. Each case occurred approximately 1 to 2 weeks following exposure to the drug. All five patients survived. A brief review of drug-induced immune hemolytic anemia (DIIHA) is also discussed. Conclusion: DIIHA may be difficult to distinguish from other causes of hemolytic anemia, but should be included in the differential in patients exposed to medications associated with DIIHA. Once suspected, antibody testing should be performed, and once diagnosed, further exposure should be avoided.

scholarly journals Drug Induced Encephalopathy in Patients with Chronic Kidney Disease: A Case Series

2018 ◽  
Vol 8 (2) ◽  
pp. 172-176
Author(s):  
Wasim Md Mohosin Ul Haque ◽  
Tabassum Samad ◽  
Muhammad Abdur Rahim ◽  
Shudhanshu Kumar Saha ◽  
Sarwar Iqbal
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Renal Impairment ◽  
Side Effect ◽  
Case Series ◽  
Special Group ◽  
Drug Induced ◽  
Reduced Dose

Drug induced encephalopathy is an established side effect of many drugs when used in a higher dose. Though we do not encounter this side effect frequently in our day to day practice, yet with renal impairment this is not uncommon. Even with a reduced dose many of these can precipitate encephalopathy in this special group of patients. We are presenting here a series of seven such cases of drug induced encephalopathy in patients with renal impairment.Birdem Med J 2018; 8(2): 172-176

scholarly journals Drug-induced immune hemolytic anemia (Direct Antiglobulin Test positive)

2013 ◽  
Vol 69 (2) ◽  
pp. 190-192 ◽  
Author(s):  
R.S. Sarkar ◽  
J. Philip ◽  
R.S. Mallhi ◽  
Neelesh Jain
Keyword(s):  
Hemolytic Anemia ◽  
Direct Antiglobulin Test ◽  
Drug Induced ◽  
Immune Hemolytic Anemia ◽  
Antiglobulin Test

scholarly journals Drug-induced immune hemolytic anemia because of efavirenz

AIDS ◽  
2020 ◽  
Vol 34 (2) ◽  
pp. 326-328 ◽  
Author(s):  
Kyaw S. Lin ◽  
Sein Win ◽  
Phyo P. Nyein
Keyword(s):  
Hemolytic Anemia ◽  
Drug Induced ◽  
Immune Hemolytic Anemia

Immune hemolytic anemia with drug-induced antibodies to carboplatin and vincristine in a pediatric patient with an optic pathway glioma

Transfusion ◽  
2014 ◽  
Vol 54 (11) ◽  
pp. 2901-2905 ◽  
Author(s):  
Marisol Betensky ◽  
Char Witmer ◽  
Michael J. Fisher ◽  
Sandra Nance ◽  
Mitchell J. Weiss ◽  
...  
Keyword(s):  
Pediatric Patient ◽  
Hemolytic Anemia ◽  
Optic Pathway Glioma ◽  
Optic Pathway ◽  
Drug Induced ◽  
Immune Hemolytic Anemia

scholarly journals Ibuprofen-Induced Hemolytic Anemia

2013 ◽  
Vol 2013 ◽  
pp. 1-3
Author(s):  
Aram Barbaryan ◽  
Chioma Iyinagoro ◽  
Nwabundo Nwankwo ◽  
Alaa M. Ali ◽  
Raya Saba ◽  
...  
Keyword(s):  
Hemolytic Anemia ◽  
Blood Count ◽  
Complete Blood Count ◽  
Rare Condition ◽  
Shortness Of Breath ◽  
Drug Induced ◽  
Immune Hemolytic Anemia ◽  
Patient Reported ◽  
Mucous Membranes ◽  
New Onset

Drug-induced immune hemolytic anemia is a rare condition with an incidence of 1 per million of the population. We report the case of a 36-year-old female who presented to the emergency department complaining of shortness of breath and dark colored urine. Physical examination was significant for pale mucous membranes. The patient reported using ibuprofen for a few days prior to presentation. Complete blood count performed before starting ibuprofen revealed normal platelets and hemoglobin values. On admission, the patient had evidence of hemolytic anemia with hemoglobin of 4.9 g/dL, hematocrit of 14.2%, lactate dehydrogenase 435 IU/L, and reticulocytosis 23.2%. Further testing ruled out autoimmune disease, lymphoma, and leukemia as etiologies for the patient’s new onset hemolytic anemia. Ibuprofen was immediately stopped with a gradual hematologic recovery within 3 days.

Association of positive direct antiglobulin test (DAT) with nonreactive eluate and drug-induced immune hemolytic anemia (DIHA)

2020 ◽  
pp. 103015
Author(s):  
Cristiane da Silva Rodrigues de Araújo ◽  
Bruna Accorsi Machado ◽  
Tamaris Fior ◽  
Júlia Mognon Mattiello ◽  
Mosseli Meinhart ◽  
...  
Keyword(s):  
Hemolytic Anemia ◽  
Direct Antiglobulin Test ◽  
Drug Induced ◽  
Immune Hemolytic Anemia ◽  
Antiglobulin Test ◽  
Positive Direct
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