scholarly journals NERVE CONDUCTION STUDY IN DIFFERENT CLINICAL GRADES OF DIABETIC FOOT

2019 ◽  
pp. 61-63
Author(s):  
Hemchandra. V. Nerlekar ◽  
Shekhar gouda

Background:Diabetic neuropathy is one of the commonest late complications of diabetes. Diabetic neuropathy can be either peripheral or autonomic. Nerve conduction study (NCS) is the recording and measurement of the compound nerve and muscle action potentials elicited in response to an electrical stimulus. Currently, the principal uses of NCV (Nerve Conduction velocity) study are to evaluate paresthesias (numbness, tingling, burning) and /or weakness of arms or legs. Methods: All patients diagnosed as diabetic foot were sent for Nerve Conduction Study after obtaining their written informed consent. Three nerves were studied; two motor nerves, Common peroneal and Tibial nerves, and one purely sensory nerve, Sural nerve. Results: Mixed type neuropathy with bilateral lower limb involvement was the most common type encountered. Interpretation and Conclusion: Mixed type of neuropathy was the most common in my study with respect to sensory and motor types of neuropathy; and also axonal and demyelinating types of neuropathy. Number of patients with bilateral neuropathy detected by NCV study in my study is more than that detected clinically and the difference is significant by applying the test of significance. Hence, NCV is a better study to detect nerve conduction abnormalities than clinical examination in diabetic foot.

2009 ◽  
Vol 120 (7) ◽  
pp. 1342-1345 ◽  
Author(s):  
Christian P. Kamm ◽  
Olivier Scheidegger ◽  
Kai M. Rösler

2018 ◽  
Vol 27 (4) ◽  
pp. 38-47
Author(s):  
Stella Papageorgiou ◽  
Konstantinos Krikonis ◽  
Jean-François Quinton ◽  
Kirsten Gnirs

Author(s):  
Umamaheshwari C. ◽  
Shanthi M. ◽  
Malathi M.

Background: Chemotherapy induced peripheral neuropathy is a significant disability after the treatment of large number of cancers and they have an impact on quality of life. The aim of the present endeavour was to study the cisplatin-paclitaxel induced peripheral neuropathy in patients with lung or ovarian cancerMethods: The study was carried out in the Department of Oncology, Government Rajaji Hospital, Madurai, after obtaining clearance from Institutional ethical committee, Government Rajaji Hospital, Madurai. Thirty newly diagnosed patients suffering from Lung or ovarian cancer attending Oncology department were selected. After satisfying inclusion and exclusion criteria. Patient received injection cisplatin 60 mg/m2 and injection paclitaxel 175 mg/m2. Nerve conduction study was done to assess the peripheral neuropathy. It was done before starting the chemotherapy. Patients with grade 0 neuropathy were included for the study. Nerve conduction study was repeated after each cycle. The time taken to develop peripheral neuropathy was assessed using Cancer Institute - Common Toxicity Criteria version 3.0. The data were analyzed with SPSS statistical software package (Version 16.0 SPSS Inc., Chicago, USA ).Results: There is a statistically significant reduction in sensory nerve (sural) amplitude (SNAP) and latency (p <0.05) indicating significant axonal damage. The time taken to develop peripheral neuropathy was 3 cycles with grade 3/4.Conclusions: In this present study, the neurotoxicity induced by cisplatin-paclitaxel in patients with lung or ovarian carcinoma was observed, so that early intervention can prevent the permanent neurotoxicity.


2004 ◽  
Vol 29 (5) ◽  
pp. 716-720 ◽  
Author(s):  
Henry C. Tong ◽  
Robert A. Werner ◽  
Alfred Franzblau

2012 ◽  
Vol 123 (5) ◽  
pp. 973-978 ◽  
Author(s):  
Hideharu Murashima ◽  
Masahiro Sonoo ◽  
Hiroshi Tsukamoto ◽  
Shingo Kawakami ◽  
Yasuomi Kawamura ◽  
...  

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