scholarly journals Comparison of two different dosages of the tranexamic acid on reducing of bleeding during spinal fusion surgery

2019 ◽  
Vol 41 (3) ◽  
pp. 78-84
Author(s):  
Ali mohamadian Erdi ◽  
Mahzad Yousefian ◽  
Mir Hossein Mossavi ◽  
Atefeh Shadman
Keyword(s):  
Tranexamic Acid ◽  
Spinal Fusion ◽  
Fusion Surgery ◽  
Spinal Fusion Surgery

scholarly journals Tranexamic acid reduces blood loss and transfusion in adult patients having spinal fusion surgery

2006 ◽  
Vol 53 (1) ◽  
pp. 26385-26385 ◽  
Author(s):  
Jean Wong ◽  
El-Beheiry Hossam ◽  
Yogendran Suntheralingam ◽  
Raja Rampersaud ◽  
Frances Chung
Keyword(s):  
Blood Loss ◽  
Tranexamic Acid ◽  
Spinal Fusion ◽  
Adult Patients ◽  
Fusion Surgery ◽  
Spinal Fusion Surgery

Tranexamic Acid Reduces Perioperative Blood Loss in Adult Patients Having Spinal Fusion Surgery

2008 ◽  
Vol 107 (5) ◽  
pp. 1479-1486 ◽  
Author(s):  
Jean Wong ◽  
Hossam El Beheiry ◽  
Yoga Raja Rampersaud ◽  
Stephen Lewis ◽  
Henry Ahn ◽  
...  
Keyword(s):  
Blood Loss ◽  
Tranexamic Acid ◽  
Spinal Fusion ◽  
Adult Patients ◽  
Fusion Surgery ◽  
Spinal Fusion Surgery ◽  
Perioperative Blood Loss

The Efficiency of Simultaneous Systemic and Topical Use of Tranexamic Acid in Spinal Fusion Surgery

2021 ◽  
Author(s):  
Uzay Erdogan ◽  
Seckin Sari ◽  
Ahmet Akbas
Keyword(s):  
Blood Loss ◽  
Tranexamic Acid ◽  
Spinal Fusion ◽  
Adult Patients ◽  
Conservation Strategy ◽  
Postoperative Blood Loss ◽  
Allogenic Blood Transfusion ◽  
Fusion Surgery ◽  
Drainage Fluid ◽  
Spinal Fusion Surgery

Abstract Background and Aim Multilevel posterior spinal fusion surgery in adults is associated with significant intra- and postoperative blood loss. Tranexamic acid (TXA) is an antifibrinolytic agent for reducing blood loss and allogenic blood transfusion. The purpose of this study was to evaluate the efficiency of TXA in reducing blood loss and improving hematologic parameters in adult patients undergoing posterior thoracic/lumbar instrumented spinal fusion surgery. Patients and Methods This is a retrospective observational study comparing the intra- and postoperative hemodynamic findings of two groups treated with and without TXA. The study included 112 adult patients receiving elective posterior thoracic/lumbar instrumented spinal fusion surgery. The patients were evaluated in terms of age, gender, type of surgery, intraoperative blood loss, pre- and postoperative hemoglobin (Hb) and hematocrit values, postoperative systemic anticoagulant use, intra- and postoperative use of blood products, and the volume of the drainage fluid as an indicator of postoperative blood loss. The TXA group received preoperative 10 mg/kg intravenous TXA, another dose of 10 mg/kg/h in isotonic solution during the operation, and local administration of TXA before the closure of the surgical site (1g in patients undergoing surgery in ≤3 segments, and 2g in patients undergoing surgery in ≥4 segment group). Results Intra- and postoperative blood loss and need for transfusion were significantly lower in the TXA group. Fifty-three of 112 patients required intra- and postoperative transfusion, and postoperative anticoagulants were given to 25/112 patients. The postoperative Hb level was lower, and the difference of pre- and postoperative Hb values was higher in the non-TXA group (not significant). Conclusion Simultaneous systemic and topical application of TXA is a safe and efficient blood conservation strategy for adult patients undergoing major multilevel spinal surgery.

Does Tranexamic Acid Increase the Incidence of Thromboembolism After Spinal Fusion Surgery?

2020 ◽  
Vol 33 (2) ◽  
pp. E71-E75 ◽  
Author(s):  
Bong-Seong Ko ◽  
Kyu-Jung Cho ◽  
Young-Tae Kim ◽  
Jae-Woo Park ◽  
Nak-Chul Kim
Keyword(s):  
Tranexamic Acid ◽  
Spinal Fusion ◽  
Fusion Surgery ◽  
Spinal Fusion Surgery

scholarly journals Tranexamic acid reduces blood cost in long-segment spinal fusion surgery

Medicine ◽  
2020 ◽  
Vol 99 (37) ◽  
pp. e22069
Author(s):  
Linyu Yang ◽  
Xufeng Jia ◽  
Jian Yang ◽  
Jianping Kang
Keyword(s):  
Tranexamic Acid ◽  
Spinal Fusion ◽  
Fusion Surgery ◽  
Spinal Fusion Surgery

scholarly journals Compared to Conventional Dressing Techniques, Tranexamic Acid Injection Provide Better Surgical Outcomes in Spinal Fusion Surgery

2018 ◽  
Vol 11 (4) ◽  
pp. 2215-2220
Author(s):  
Ahmad Fauzi ◽  
Adam Moelyono ◽  
S. Dohar Tobing
Keyword(s):  
Tranexamic Acid ◽  
Spinal Fusion ◽  
Surgical Outcomes ◽  
Acid Group ◽  
Adhesive Tape ◽  
Fusion Surgery ◽  
Spinal Fusion Surgery ◽  
Acid Injection ◽  
Group 2 ◽  
Sterile Gauze

The use of mechanical and chemical hemostatic control techniques in spinal fusion surgery is common in Indonesia. However, there has been no study comparing the two in a single clinical trials. This study aims to find out which best of tranexamic acid injection, a bulky compression dressing and a standard dressing in providing surgical outcomes in spinal fusion surgery. Thirty patients were grouped into three, 10 patients each. To Group 1, tranexamic acid at a dose of 500 mg/ml was administered pre operation and 2 hours later. For Group 2, a bulky compression dressing was performed by covering the surgical wounds with a low-adherent dressing, overlaid with four layers of sterile gauze and then sealed with a conformable adhesive retention tape. Standard dressing was applied to the patients of Group-3 using the same type of bandage and adhesive tape given to the Group-2, but only overlaid with two layers of sterile gauze. There is no statistical difference among trials groups for preoperative (P > 0.220) and postoperative (P > 0.380) hemoglobin levels and the level of perioperative blood loss (P > 0.110). With respect to number of transfusion required, the tranexamic acid group was significantly lower compared to the standard dressing group (P = 0.018). No abnormality of wound seen in all three trials groups and only 2 patients of bulky compression dressing group reported experience of headache. In conclusion, tranexamic acid is better to promote hemostasis compared to conventional dressing techniques.

scholarly journals Topical use of tranexamic acid can effectively decrease hidden blood loss during posterior lumbar spinal fusion surgery

Medicine ◽  
2017 ◽  
Vol 96 (42) ◽  
pp. e8233 ◽  
Author(s):  
Zhinan Ren ◽  
Shugang Li ◽  
Lin Sheng ◽  
Qianyu Zhuang ◽  
Zheng Li ◽  
...  
Keyword(s):  
Blood Loss ◽  
Tranexamic Acid ◽  
Spinal Fusion ◽  
Lumbar Spinal Fusion ◽  
Fusion Surgery ◽  
Spinal Fusion Surgery ◽  
Hidden Blood Loss ◽  
Lumbar Spinal
Sign in / Sign up

Export Citation Format

Share Document