scholarly journals Cost-Benefit Analysis of Using A Single Dose of Tranexamic Acid in Degenerative Lumbar Scoliosis Patients Undergoing Long-Segment Spinal Fusion Surgery: A Retrospective Study

2021 ◽  
Vol 27 ◽  
Author(s):  
Lei Yuan ◽  
Yu Jiang ◽  
Yinhao Liu ◽  
Yan Zeng ◽  
Zhongqiang Chen ◽  
...  
Keyword(s):  
Single Dose ◽  
Retrospective Study ◽  
Tranexamic Acid ◽  
Spinal Fusion ◽  
Cost Benefit Analysis ◽  
Cost Benefit ◽  
Degenerative Lumbar Scoliosis ◽  
Benefit Analysis ◽  
Fusion Surgery ◽  
Spinal Fusion Surgery

scholarly journals Tranexamic acid reduces blood loss and transfusion in adult patients having spinal fusion surgery

2006 ◽  
Vol 53 (1) ◽  
pp. 26385-26385 ◽  
Author(s):  
Jean Wong ◽  
El-Beheiry Hossam ◽  
Yogendran Suntheralingam ◽  
Raja Rampersaud ◽  
Frances Chung
Keyword(s):  
Blood Loss ◽  
Tranexamic Acid ◽  
Spinal Fusion ◽  
Adult Patients ◽  
Fusion Surgery ◽  
Spinal Fusion Surgery

Tranexamic Acid Reduces Perioperative Blood Loss in Adult Patients Having Spinal Fusion Surgery

2008 ◽  
Vol 107 (5) ◽  
pp. 1479-1486 ◽  
Author(s):  
Jean Wong ◽  
Hossam El Beheiry ◽  
Yoga Raja Rampersaud ◽  
Stephen Lewis ◽  
Henry Ahn ◽  
...  
Keyword(s):  
Blood Loss ◽  
Tranexamic Acid ◽  
Spinal Fusion ◽  
Adult Patients ◽  
Fusion Surgery ◽  
Spinal Fusion Surgery ◽  
Perioperative Blood Loss

The Efficiency of Simultaneous Systemic and Topical Use of Tranexamic Acid in Spinal Fusion Surgery

2021 ◽  
Author(s):  
Uzay Erdogan ◽  
Seckin Sari ◽  
Ahmet Akbas
Keyword(s):  
Blood Loss ◽  
Tranexamic Acid ◽  
Spinal Fusion ◽  
Adult Patients ◽  
Conservation Strategy ◽  
Postoperative Blood Loss ◽  
Allogenic Blood Transfusion ◽  
Fusion Surgery ◽  
Drainage Fluid ◽  
Spinal Fusion Surgery

Abstract Background and Aim Multilevel posterior spinal fusion surgery in adults is associated with significant intra- and postoperative blood loss. Tranexamic acid (TXA) is an antifibrinolytic agent for reducing blood loss and allogenic blood transfusion. The purpose of this study was to evaluate the efficiency of TXA in reducing blood loss and improving hematologic parameters in adult patients undergoing posterior thoracic/lumbar instrumented spinal fusion surgery. Patients and Methods This is a retrospective observational study comparing the intra- and postoperative hemodynamic findings of two groups treated with and without TXA. The study included 112 adult patients receiving elective posterior thoracic/lumbar instrumented spinal fusion surgery. The patients were evaluated in terms of age, gender, type of surgery, intraoperative blood loss, pre- and postoperative hemoglobin (Hb) and hematocrit values, postoperative systemic anticoagulant use, intra- and postoperative use of blood products, and the volume of the drainage fluid as an indicator of postoperative blood loss. The TXA group received preoperative 10 mg/kg intravenous TXA, another dose of 10 mg/kg/h in isotonic solution during the operation, and local administration of TXA before the closure of the surgical site (1g in patients undergoing surgery in ≤3 segments, and 2g in patients undergoing surgery in ≥4 segment group). Results Intra- and postoperative blood loss and need for transfusion were significantly lower in the TXA group. Fifty-three of 112 patients required intra- and postoperative transfusion, and postoperative anticoagulants were given to 25/112 patients. The postoperative Hb level was lower, and the difference of pre- and postoperative Hb values was higher in the non-TXA group (not significant). Conclusion Simultaneous systemic and topical application of TXA is a safe and efficient blood conservation strategy for adult patients undergoing major multilevel spinal surgery.

Does Tranexamic Acid Increase the Incidence of Thromboembolism After Spinal Fusion Surgery?

2020 ◽  
Vol 33 (2) ◽  
pp. E71-E75 ◽  
Author(s):  
Bong-Seong Ko ◽  
Kyu-Jung Cho ◽  
Young-Tae Kim ◽  
Jae-Woo Park ◽  
Nak-Chul Kim
Keyword(s):  
Tranexamic Acid ◽  
Spinal Fusion ◽  
Fusion Surgery ◽  
Spinal Fusion Surgery

Cost-benefit analysis of the use of tranexamic acid in total replacement hip surgery

2019 ◽  
Vol 57 ◽  
pp. 124-128 ◽  
Author(s):  
Amanda Lopez-Picado ◽  
Borja Barrachina ◽  
Maria Remón ◽  
Maria Errea
Keyword(s):  
Tranexamic Acid ◽  
Cost Benefit Analysis ◽  
Cost Benefit ◽  
Hip Surgery ◽  
Benefit Analysis ◽  
Total Replacement
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