Faculty Opinions recommendation of Dietary long-chain PUFA enhance acute repair of ischemia-injured intestine of suckling pigs.

2012 ◽  
Author(s):  
Kim Barrett
Keyword(s):  
Chain Pufa ◽  
Long Chain

Prospective enzymes for omega-3 PUFA biosynthesis found in endoparasitic classes within the phylum Platyhelminthes

2020 ◽  
Vol 94 ◽  
Author(s):  
D. Babaran ◽  
M.T. Arts ◽  
R.J. Botelho ◽  
S.A. Locke ◽  
J. Koprivnikar
Keyword(s):  
Parasite Species ◽  
De Novo ◽  
Genomic Data ◽  
Wide Distribution ◽  
Omega 3 ◽  
Free Living ◽  
Chain Pufa ◽  
Pufa Biosynthesis ◽  
Aquatic Food ◽  
Long Chain

Abstract The free-living infectious stages of macroparasites, specifically, the cercariae of trematodes (flatworms), are likely to be significant (albeit underappreciated) vectors of nutritionally important polyunsaturated fatty acids (PUFA) to consumers within aquatic food webs, and other macroparasites could serve similar roles. In the context of de novo omega-3 (n-3) PUFA biosynthesis, it was thought that most animals lack the fatty acid (FA) desaturase enzymes that convert stearic acid (18:0) into ɑ-linolenic acid (ALA; 18:3n-3), the main FA precursor for n-3 long-chain PUFA. Recently, novel sequences of these enzymes were recovered from 80 species from six invertebrate phyla, with experimental confirmation of gene function in five phyla. Given this wide distribution, and the unusual attributes of flatworm genomes, we conducted an additional search for genes for de novo n-3 PUFA in the phylum Platyhelminthes. Searches with experimentally confirmed sequences from Rotifera recovered nine relevant FA desaturase sequences from eight species in four genera in the two exclusively endoparasite classes (Trematoda and Cestoda). These results could indicate adaptations of these particular parasite species, or may reflect the uneven taxonomic coverage of sequence databases. Although additional genomic data and, particularly, experimental study of gene functionality are important future validation steps, our results indicate endoparasitic platyhelminths may have enzymes for de novo n-3 PUFA biosynthesis, thereby contributing to global PUFA production, but also representing a potential target for clinical antihelmintic applications.

scholarly journals n‐3 PUFA Supplementation Alters Retinal Very‐Long‐Chain‐PUFA Levels and Ratios in Diabetic Animal Models

2019 ◽  
Vol 63 (15) ◽  
pp. 1801058 ◽  
Author(s):  
Aruna Gorusupudi ◽  
Fu‐Yen Chang ◽  
Kelly Nelson ◽  
Gregory S. Hageman ◽  
Paul S. Bernstein
Keyword(s):  
Animal Models ◽  
Diabetic Animal ◽  
Pufa Supplementation ◽  
Chain Pufa ◽  
Long Chain

Dietary long-chain PUFA in the form of TAG or phospholipids influence lymph lipoprotein size and composition in piglets

Lipids ◽  
2002 ◽  
Vol 37 (10) ◽  
pp. 975-980 ◽  
Author(s):  
Laura Amate ◽  
Angel Gil ◽  
María Ramírez
Keyword(s):  
Chain Pufa ◽  
Lipoprotein Size ◽  
Long Chain

scholarly journals The Source of Long-Chain PUFA in Formula Supplements Does Not Affect the Fatty Acid Composition of Plasma Lipids in Full-Term Infants

2004 ◽  
Vol 134 (4) ◽  
pp. 868-873 ◽  
Author(s):  
Aleix Sala-Vila ◽  
Ana I. Castellote ◽  
Cristina Campoy ◽  
Montserrat Rivero ◽  
María Rodriguez-Palmero ◽  
...  
Keyword(s):  
Fatty Acid Composition ◽  
Fatty Acid ◽  
Acid Composition ◽  
Plasma Lipids ◽  
Full Term ◽  
Term Infants ◽  
Chain Pufa ◽  
Long Chain

scholarly journals Maternal but Not Fetal FADS Gene Variants Modify the Association between Maternal Long-Chain PUFA Intake in Pregnancy and Birth Weight

2014 ◽  
Vol 144 (9) ◽  
pp. 1430-1437 ◽  
Author(s):  
Carolina Moltó-Puigmartí ◽  
Martien C. J. M. van Dongen ◽  
Pieter C. Dagnelie ◽  
Jogchum Plat ◽  
Ronald P. Mensink ◽  
...  
Keyword(s):  
Birth Weight ◽  
Gene Variants ◽  
Pufa Intake ◽  
Chain Pufa ◽  
Long Chain ◽  
Pregnancy And Birth ◽  
In Pregnancy

Long-chain PUFA in Granulocytes, Mononuclear Cells, and RBC in Patients With Cystic Fibrosis

2012 ◽  
Vol 55 (1) ◽  
pp. 76-81 ◽  
Author(s):  
Marianne H. Jørgensen ◽  
Peter Ott ◽  
Kim F. Michaelsen ◽  
Trine Porsgaard ◽  
Fleming Jensen ◽  
...  
Keyword(s):  
Cystic Fibrosis ◽  
Mononuclear Cells ◽  
Chain Pufa ◽  
Long Chain

scholarly journals Serum n-3 long-chain PUFA differ by sex and age in a population-based survey of New Zealand adolescents and adults

2007 ◽  
Vol 99 (1) ◽  
pp. 168-174 ◽  
Author(s):  
Francesca L. Crowe ◽  
C. Murray Skeaff ◽  
Timothy J. Green ◽  
Andrew R. Gray
Keyword(s):  
Age Differences ◽  
Cholesterol Ester ◽  
Disease Risk ◽  
Dietary Factors ◽  
Nutrition Survey ◽  
Men And Women ◽  
Chain Pufa ◽  
Epa And Dha ◽  
Sex And Age Differences ◽  
Long Chain

A higher proportion of n-3 long-chain PUFA in tissue lipids has been associated with a lower risk of CVD and some cancers. Diet is an important predictor of n-3 long-chain PUFA composition; however, the importance of non-dietary factors such as sex and age is unclear. We measured the proportion of n-3 long-chain PUFA in serum phospholipid, cholesterol ester and TAG of 2793 New Zealanders 15 years or older who participated in the 1997 National Nutrition Survey to determine differences by sex and age. Women had lower proportions of EPA and docosapentaenoic acid in phospholipid, by 0·07 (P = 0·004) and 0·10 (P < 0·001) mol%, respectively, and a higher proportion of DHA by 0·16 mol% (P = 0·001) compared with men. Intake of fish fat did not differ between men and women. There was a positive association between age and the proportion of EPA and DHA in phospholipid (P < 0·001). The sex differences in EPA and DHA were similar at all ages. Similar sex and age differences in serum cholesterol ester n-3 long-chain PUFA were found; only age differences were found in serum TAG. Sex and age differences in n-3 long-chain PUFA occur in the general population. Men and women may need to be considered separately when examining the association between disease risk and biomarkers of n-3 fatty acids.

The effect of long-chain polyunsaturated fatty acid and vitamin E supplementation of ewes on neonatal lamb vigour, lamb growth and colostrum parameters

2002 ◽  
Vol 2002 ◽  
pp. 7-7 ◽  
Author(s):  
J. L. Capper ◽  
R. G. Wilkinson ◽  
L. A. Sinclair ◽  
S. E. Pattinson ◽  
A. M. Mackenzie
Keyword(s):  
Fatty Acids ◽  
Vitamin E ◽  
Chain Polyunsaturated Fatty Acid ◽  
Alpha Linolenic Acid ◽  
Chain Pufa ◽  
Ruminant Diets ◽  
The Brain ◽  
Lamb Growth ◽  
Long Chain ◽  
Vitamin E Supplementation

The long-chain polyunsaturated fatty acids (PUFA) docosahexaenoic acid (DHA) and arachidonic acid (AA) are the most abundant fatty acids in the brain and are vital for its correct development and for that of the nervous system (Huang and Craig-Schmidt, 1996). Ruminant diets are low in DHA and its precursor alpha-linolenic acid. In addition, dietary PUFAs are substantially hydrogenated in the rumen. Consequently, it may be argued that the diets of pregnant and lactating ewes may be deficient in DHA and that a response to supplementation may be observed. Studies involving the supplementation of pregnant ewes with supraoptimal levels of vitamin E have shown that lambs born to supplemented dams are more vigorous immediately after birth and have higher liveweight gains (Merrell, 1998). The objective of this experiment was to investigate the effects of dietary long-chain PUFA in combination with vitamin E supplementation of ewes on ewe and lamb performance.

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