scholarly journals Electro-Oxidation and Simultaneous Determination of Indole-3-Acetic Acid and Salicylic Acid on Graphene Hydrogel Modified Electrode

Sensors ◽  
2019 ◽  
Vol 19 (24) ◽  
pp. 5483 ◽  
Author(s):  
Xiaodong Cao ◽  
Xueting Zhu ◽  
Shudong He ◽  
Xuan Xu ◽  
Yongkang Ye
Keyword(s):  
Acetic Acid ◽  
Salicylic Acid ◽  
Modified Electrode ◽  
Limit Of Detection ◽  
Simultaneous Detection ◽  
Three Dimensional ◽  
Linear Sweep Voltammetry ◽  
Oxidation Reactions ◽  
Sensor Performance ◽  
Indole 3 Acetic Acid

A selective and sensitive electrochemical sensor was developed for simultaneous detection of phytohormones indole-3-acetic acid (IAA) and salicylic acid (SA). The sensing interface was fabricated on a porous, three-dimensional networked graphene hydrogel (GH) modified glassy carbon electrode (GCE). The electrocatalytic behavior of IAA and SA on the surface of the modified electrode (GH/GCE) was investigated by cyclic voltammetry and linear sweep voltammetry. Results show that the oxidation reactions of IAA and SA occur at different potentials, which enable their simultaneous detection at the sensing interface. Under optimal conditions, the GH/GCE exhibited good selectivity and stability and its response, unaffected by various interferents, was linear in the range of 4 to 200 μM of IAA and SA. The limit of detection (S/N = 3) achieved were 1.42 μM for IAA and 2.80 μM for SA. The sensor performance was validated by measuring for IAA and SA in real vegetable samples with satisfactory results.

Gold nanoparticle-doped three-dimensional reduced graphene hydrogel modified electrodes for amperometric determination of indole-3-acetic acid and salicylic acid

Nanoscale ◽  
2019 ◽  
Vol 11 (21) ◽  
pp. 10247-10256 ◽  
Author(s):  
Xiaodong Cao ◽  
Xueting Zhu ◽  
Shudong He ◽  
Xuan Xu ◽  
Yongkang Ye ◽  
...  
Keyword(s):  
Acetic Acid ◽  
Salicylic Acid ◽  
Gold Nanoparticle ◽  
Three Dimensional ◽  
Modified Electrodes ◽  
Amperometric Determination ◽  
Reduced Graphene ◽  
Indole 3 Acetic Acid

Three-dimensional (3D) networked nanomaterials have attracted great interest because of their unique porous and 3D-networked structures.

scholarly journals An Electrochemical Strategy for the Simultaneous Detection of Doxorubicin and Simvastatin for Their Potential Use in the Treatment of Cancer

Biosensors ◽  
2021 ◽  
Vol 11 (1) ◽  
pp. 15
Author(s):  
Iulia Rus ◽  
Mihaela Tertiș ◽  
Cristina Barbălată ◽  
Alina Porfire ◽  
Ioan Tomuță ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Electrolyte Solution ◽  
Electrode Material ◽  
Dynamic Range ◽  
Limit Of Detection ◽  
Simultaneous Detection ◽  
Linear Sweep Voltammetry ◽  
Pharmaceutical Formulations ◽  
Promising Tool ◽  
Scan Rate

The aim of this study was to develop a disposable, simple, fast, and sensitive sensor for the simultaneous electrochemical detection of doxorubicin (DOX) and simvastatin (SMV), which could be used in preclinical studies for the development of new pharmaceutical formulations for drug delivery. Firstly, the electrochemical behavior of each molecule was analyzed regarding the influence of electrode material, electrolyte solution, and scan rate. After this, the proper electrode material, electrolyte solution, and scan rate for both active substances were chosen, and a linear sweep voltammetry procedure was optimized for simultaneous detection. Two chronoamperometry procedures were tested, one for the detection of DOX in the presence of SMV, and the other one for the detection of DOX and SMV together. Finally, calibration curves for DOX and SMV in the presence of each other were obtained using both electrochemical methods and the results were compared. The use of amperometry allowed for a better limit of detection (DOX: 0.1 μg/mL; SMV: 0.7 μg/mL) than the one obtained in voltammetry (1.5 μg/mL for both drugs). The limits of quantification using amperometry were 0.5 μg/mL for DOX (dynamic range: 0.5–65 μg/mL) and 2 μg/mL for SMV (dynamic range: 2–65 μg/mL), while using voltammetry 1 μg/mL was obtained for DOX (dynamic range: 1–100 μg/mL) and 5 μg/mL for SMV (dynamic range: 5–100 μg/mL). This detection strategy represents a promising tool for the analysis of new pharmaceutical formulations for targeted drug delivery containing both drugs, whose association was proven to bring benefits in the treatment of cancer.

scholarly journals An Analysis of a Compact Label-Free Guiding-Wave Biosensor Based on a Semiconductor-Clad Dielectric Strip Waveguide

Sensors ◽  
2020 ◽  
Vol 20 (12) ◽  
pp. 3368 ◽  
Author(s):  
Carlos Angulo Barrios
Keyword(s):  
Limit Of Detection ◽  
Beam Propagation Method ◽  
Three Dimensional ◽  
Silicon Oxynitride ◽  
Practical Implementation ◽  
Label Free ◽  
Sensor Performance ◽  
Strip Waveguide ◽  
Fabrication Tolerances ◽  
Photonic Biosensors

In this paper, a compact, integrated, semiconductor-clad strip waveguide label-free biosensor is proposed and analyzed. The device is based on CMOS-compatible materials such as amorphous-Si and silicon oxynitride. The optical sensor performance has been modeled by a three-dimensional beam propagation method. The simulations indicate that a 20-μm-long device can exhibit a surface limit of detection of 3 ng/cm2 for avidin molecules in aqueous solution. The sensor performance compares well to those displayed by other photonic biosensors with much larger footprints. The fabrication tolerances have been also studied in order to analyze the feasibility of the practical implementation of the biosensor.

scholarly journals Analysis of the horseradish peroxidase/indole-3-acetic acid combination in a three-dimensional tumor model

2004 ◽  
Vol 11 (7) ◽  
pp. 508-513 ◽  
Author(s):  
Joanna Tupper ◽  
Olga Greco ◽  
Gillian M Tozer ◽  
Gabi U Dachs
Keyword(s):  
Acetic Acid ◽  
Horseradish Peroxidase ◽  
Three Dimensional ◽  
Tumor Model ◽  
Indole 3 Acetic Acid

scholarly journals SIMULTANEOUS ELECTROCHEMICAL DETECTION OF ASCORBIC ACID, DOPAMINE, AND URIC ACID AT MAGNETIC NANOPARTICLES/REDUCED GRAPHENE OXIDE MODIFIED ELECTRODE

2021 ◽  
Vol 83 (3) ◽  
pp. 85-92
Author(s):  
Azleen Rashidah Mohd Rosli ◽  
Farhanini Yusoff ◽  
Saw Hong Loh ◽  
Hanis Mohd Yusoff ◽  
Muhammad Mahadi Abdul Jamil ◽  
...  
Keyword(s):  
Ascorbic Acid ◽  
Uric Acid ◽  
Graphene Oxide ◽  
Magnetic Nanoparticles ◽  
Reduced Graphene Oxide ◽  
Modified Electrode ◽  
Limit Of Detection ◽  
Simultaneous Detection ◽  
Differential Pulse ◽  
Reduced Graphene

A magnetic nanoparticles/reduced graphene oxide modified glassy carbon electrode (MNP/rGO/GCE) was fabricated via one-step facile synthesis route for the simultaneous determination of ascorbic acid (AA), dopamine (DA), along with uric acid (UA). A series of diseases and disorders has been associated with irregular levels of these respective analytes, thus early detection is highly crucial. Physical and electrochemical characterization of the modified electrode was conducted by using Scanning Electron Microscopy (SEM), Fourier Transform Infrared (FTIR) analysis, X-Ray Diffraction (XRD) analysis and Brauneur-Emmet-Teller (BET), Cyclic Voltammetry (CV) and Electron Impedance Spectroscopy (EIS). The results obtained confirmed the formation of MNP/rGO composite. Differential pulse voltammetry (DPV) of MNP/rGO/GCE displays three well-defined peaks which associated to AA, DA and UA, respectively. The response towards DA is linear in the concentration range of 15 nM to 100 µM with a detection limit of 0.19 nM while a response to AA and UA is also linear in the concentration range of 10 µM to 100 µM with a limit of detection 0.22 µM and 45 nM respectively. The proposed modified electrode offers a good response towards simultaneous detection of three different electroactive species with excellent electron transfer rate, great capacitance and ideal diffusive control behavior.

Electrochemical mapping of indole-3-acetic acid and salicylic acid in whole pea seedlings under normal conditions and salinity

2018 ◽  
Vol 276 ◽  
pp. 545-551 ◽  
Author(s):  
Li-Jun Sun ◽  
Jia-Jing Zhou ◽  
Jin-Lin Pan ◽  
Yun-Yun Liang ◽  
Zi-Jun Fang ◽  
...  
Keyword(s):  
Acetic Acid ◽  
Salicylic Acid ◽  
Pea Seedlings ◽  
Indole 3 Acetic Acid

scholarly journals A multifunctional ratiometric electrochemical sensor for combined determination of indole-3-acetic acid and salicylic acid

RSC Advances ◽  
2020 ◽  
Vol 10 (6) ◽  
pp. 3115-3121 ◽  
Author(s):  
Ye Hu ◽  
Xiaodong Wang ◽  
Cheng Wang ◽  
Peichen Hou ◽  
Hongtu Dong ◽  
...  
Keyword(s):  
Acetic Acid ◽  
Salicylic Acid ◽  
Electrochemical Sensor ◽  
First Time ◽  
Indole 3 Acetic Acid

For the first time, a multifunctional ratiometric electrochemical sensor was developed for quantifying IAA and SA simultaneously.

scholarly journals Optimized High-Performance Liquid Chromatography Method for Determining Nine Cytokinins, Indole-3-acetic Acid and Abscisic Acid

2021 ◽  
Vol 13 (13) ◽  
pp. 6998
Author(s):  
Beibei Qi ◽  
Chao Wu ◽  
Huiling Liang ◽  
Kehui Cui ◽  
Shah Fahad ◽  
...  
Keyword(s):  
High Performance Liquid Chromatography ◽  
Acetic Acid ◽  
Abscisic Acid ◽  
Liquid Chromatography ◽  
High Performance ◽  
Limit Of Detection ◽  
Xylem Sap ◽  
Column Temperature ◽  
Relative Standard ◽  
Indole 3 Acetic Acid

Liquid-liquid extraction and solid phase extraction followed by high-performance liquid chromatography (HPLC) connected with ultraviolet (UV) detection were used for the determination of phytohormones. The parameters influencing the performance of the HPLC-UV method, including composition of the mobile phase for gradient elution, column temperature, flow rate, and detection wavelength, were optimized. This method can simultaneously determine 11 phytohormones, including nine cytokinins, indole-3-acetic acid, and abscisic acid. The limit of detection of this method is 0.22 to 1.1 µg L−1, and the coefficient factors of linear regression are >0.998. The recoveries of the target phytohormones ranged between 62.1~109.4%, and the relative standard deviations were <10%. This method is suitable for determining phytohormones, especially cytokinins, in young panicles, roots, and xylem sap of rice plants.

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