scholarly journals New Single-Layered Paper-Based Microfluidic Devices for the Analysis of Nitrite and Glucose Built via Deposition of Adhesive Tape

Sensors ◽  
2019 ◽  
Vol 19 (19) ◽  
pp. 4082 ◽  
Author(s):  
Peng Yu ◽  
Muhan Deng ◽  
Yi Yang

A simple, low-cost technique has been developed for the rapid fabrication of single-layered paper-based microfluidic devices (μPADs). This technique, for the first time, made use of the deposition of patterned adhesive tape into the filter paper to construct hydrophobic barriers, with the help of toluene. Unlike other reported multi-layered μPADs that merely made use of adhesive tape as a separate layer for sealing or fluid flow controlling, the patterned adhesive tape was simultaneously dissolved and penetrated into the filter paper, which resulted in the successful transfer of the pattern from the tape to the filter paper. To demonstrate the effectiveness of this approach, nitrite and glucose were individually measured; detection limits as low as 0.015 ± 0.004 mM and 0.022 ± 0.006 mM were reported for nitrite and glucose, respectively. Multiplexed analysis of both analytes was also carried out with respective detection limits of 0.048 ± 0.005 mM and 0.025 ± 0.006 mM for nitrite and glucose. The application of the method was demonstrated by measuring nitrite and glucose in spiked artificial urine samples and satisfied recovery results were obtained.

Micromachines ◽  
2021 ◽  
Vol 12 (5) ◽  
pp. 514
Author(s):  
Wojciech Raj ◽  
Daisy Yang ◽  
Craig Priest

Based on the virtual walls concept, where fluids are guided by wettability, we demonstrate the application of a gas phase extraction microfluidic chip. Unlike in previous work, the chip is prepared using a simple, rapid, and low-cost fabrication method. Channels were cut into double-sided adhesive tape (280 µm thick) and bonded to hydrophilic glass slides. The tape was selectively made superhydrophobic by ‘dusting’ with hydrophobic silica gel to enhance the wettability contrast at the virtual walls. Finally, the two glass slides were bonded using tape, which acts as a spacer for gas transport from/to the guided liquids. In our example, the virtual walls create a stable liquid–vapor–liquid flow configuration for the extraction of a volatile analyte (ammonia), from one liquid stream to the other through the intermediate vapor phase. The collector stream contained a pH indicator to visualize the mass transport. Quantitative analysis of ammonium hydroxide in the sample stream (<1 mM) was possible using a characteristic onset time, where the first pH change in the collector stream was detected. The effect of gap length, flow rates, and pH of the collector stream on the onset time is demonstrated. Finally, we demonstrate the analysis of ammonium hydroxide in artificial human saliva to show that the virtual walls chip is suitable for extracting volatile analytes from biofluids.


Sensors ◽  
2021 ◽  
Vol 21 (6) ◽  
pp. 1977
Author(s):  
Ricardo Oliveira ◽  
Liliana M. Sousa ◽  
Ana M. Rocha ◽  
Rogério Nogueira ◽  
Lúcia Bilro

In this work, we demonstrate for the first time the capability to inscribe long-period gratings (LPGs) with UV radiation using simple and low cost amplitude masks fabricated with a consumer grade 3D printer. The spectrum obtained for a grating with 690 µm period and 38 mm length presented good quality, showing sharp resonances (i.e., 3 dB bandwidth < 3 nm), low out-of-band loss (~0.2 dB), and dip losses up to 18 dB. Furthermore, the capability to select the resonance wavelength has been demonstrated using different amplitude mask periods. The customization of the masks makes it possible to fabricate gratings with complex structures. Additionally, the simplicity in 3D printing an amplitude mask solves the problem of the lack of amplitude masks on the market and avoids the use of high resolution motorized stages, as is the case of the point-by-point technique. Finally, the 3D printed masks were also used to induce LPGs using the mechanical pressing method. Due to the better resolution of these masks compared to ones described on the state of the art, we were able to induce gratings with higher quality, such as low out-of-band loss (0.6 dB), reduced spectral ripples, and narrow bandwidths (~3 nm).


Polymers ◽  
2021 ◽  
Vol 13 (4) ◽  
pp. 607
Author(s):  
Lucero M. Hernandez-Cedillo ◽  
Francisco G. Vázquez-Cuevas ◽  
Rafael Quintero-Torres ◽  
Jose L. Aragón ◽  
Miguel Angel Ocampo Mortera ◽  
...  

In this article, we show an alternative low-cost fabrication method to obtain poly(dimethyl siloxane) (PDMS) microfluidic devices. The proposed method allows the inscription of micron resolution channels on polystyrene (PS) surfaces, used as a mold for the wanted microchip’s production, by applying a high absorption coating film on the PS surface to ablate it with a focused low-power visible laser. The method allows for obtaining micro-resolution channels at powers between 2 and 10 mW and can realize any two-dimensional polymeric devices. The effect of the main processing parameters on the channel’s geometry is presented.


RSC Advances ◽  
2021 ◽  
Vol 11 (9) ◽  
pp. 4873-4882
Author(s):  
Gongyan Liu ◽  
Ruiquan Yu ◽  
Jing Jiang ◽  
Zhuang Ding ◽  
Jing Ma ◽  
...  

Point-of-use water disinfection by GA@AgNPs-LA-FP.


1998 ◽  
Vol 70 (1-2) ◽  
pp. 153-158 ◽  
Author(s):  
W.K. Schomburg ◽  
R. Ahrens ◽  
W. Bacher ◽  
C. Goll ◽  
S. Meinzer ◽  
...  

2016 ◽  
Vol 8 (21) ◽  
pp. 13466-13471 ◽  
Author(s):  
Gerard Cadafalch Gazquez ◽  
Sidong Lei ◽  
Antony George ◽  
Hemtej Gullapalli ◽  
Bernard A. Boukamp ◽  
...  

2009 ◽  
Vol 20 (1) ◽  
pp. 015026 ◽  
Author(s):  
Mona Rahbar ◽  
Sumanpreet Chhina ◽  
Dan Sameoto ◽  
M Parameswaran

2007 ◽  
Vol 121-123 ◽  
pp. 611-614
Author(s):  
Che Hsin Lin ◽  
Jen Taie Shiea ◽  
Yen Lieng Lin

This paper proposes a novel method to on-chip fabricate a none-dead-volume microtip for ESI-MS applications. The microfluidic chip and ESI tip are fabricated in low-cost plastic based materials using a simple and rapid fabrication process. A constant-speed-pulling method is developed to fabricate the ESI tip by pulling mixed PMMA glue using a 30-μm stainless wire through the pre-formed microfluidic channel. The equilibrium of surface tension of PMMA glue will result in a sharp tip after curing. A highly uniform micro-tip can be formed directly at the outlet of the microfluidic channel with minimum dead-volume zone. Detection of caffeine, myoglobin, lysozyme and cytochrome C biosamples confirms the microchip device can be used for high resolution ESI-MS applications.


2017 ◽  
Vol 5 (39) ◽  
pp. 20860-20866 ◽  
Author(s):  
Mahdi Fathizadeh ◽  
Huynh Ngoc Tien ◽  
Konstantin Khivantsev ◽  
Jung-Tsai Chen ◽  
Miao Yu

We demonstrated for the first time that inkjet printing can be a low-cost, easy, fast, and scalable method for depositing ultrathin (7.5–60 nm) uniform graphene oxide (GO) nanofiltration membranes on polymeric supports for highly effective water purification.


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