scholarly journals Desquamative Gingivitis: Protocols, Procedures and Critical Issues

Proceedings ◽  
2019 ◽  
Vol 35 (1) ◽  
pp. 2
Author(s):  
Paola Carcieri
Keyword(s):  
Lichen Planus ◽  
Mucous Membrane ◽  
Plasma Cell ◽  
Oral Lichen Planus ◽  
Pemphigus Vulgaris ◽  
Mucous Membrane Pemphigoid ◽  
Critical Issues ◽  
Oral Lichen

Desquamative gingivitis (DG) isn’t a specific disorder; it simply represents the gingival manifestation associated with some heterogeneous mucocutaneous disorders, such as oral lichen planus (OLP), mucous membrane pemphigoid (MMP), pemphigus vulgaris (PV), plasma cell gingivitis (PCG) and few others. [...]

scholarly journals Immune-Mediated Desquamative Gingivitis and Optical Coherence Tomography Diagnostic Patterns: Clinical Implication from a Systematic Review

Diagnostics ◽  
2021 ◽  
Vol 11 (8) ◽  
pp. 1453
Author(s):  
Vera Panzarella ◽  
Alessia Bartolone ◽  
Vito Rodolico ◽  
Giorgia Capocasale ◽  
Laura Maniscalco ◽  
...  
Keyword(s):  
Systematic Review ◽  
Optical Coherence Tomography ◽  
Lichen Planus ◽  
Mucous Membrane ◽  
Oral Lichen Planus ◽  
Pemphigus Vulgaris ◽  
Mucous Membrane Pemphigoid ◽  
Optical Coherence ◽  
Immune Mediated ◽  
Oral Lichen

Desquamative Gingivitis (DG) comprises heterogeneous clinical manifestations of numerous immune-mediated muco-cutaneous diseases. Optical Coherence Tomography (OCT) has been proposed as a valuable diagnostic support even if, to date, there are no standardized OCT-diagnostic patterns applicable to DGs. A systematic review was performed to detect existing data on in vivo OCT diagnostic patterns of the most common immune-mediated DGs (i.e., pemphigus vulgaris, mucous membrane pemphigoid and oral lichen planus). It has been found that OCT exhibits specific patterns that address the diagnosis of DG by pemphigus vulgaris (i.e., intraepithelial unilocular blister, reduced epithelial thickness, presence of acantholytic cells in the blister) and by mucous membrane pemphigoid (i.e., subepithelial multilocular blister, presence of inflammatory infiltrate), but not by oral lichen planus. These patterns could offer an attractive diagnostic OCT framework to support the clinical preliminary assessment and monitoring of these complex pathological conditions.

Four cases of mucous membrane pemphigoid with clinical features of oral lichen planus

2015 ◽  
Vol 55 (6) ◽  
pp. 657-665 ◽  
Author(s):  
Aoi Fukuda ◽  
Akio Himejima ◽  
Daisuke Tsuruta ◽  
Hiroshi Koga ◽  
Bungo Ohyama ◽  
...  
Keyword(s):  
Lichen Planus ◽  
Mucous Membrane ◽  
Clinical Features ◽  
Oral Lichen Planus ◽  
Mucous Membrane Pemphigoid ◽  
Oral Lichen

Clinical–pathologic Agreement for Oral Lesions in an Oral Medicine Setting

2016 ◽  
Vol 2 (1) ◽  
pp. 1-10 ◽  
Author(s):  
Alessandro Villa ◽  
Francesco Nordio ◽  
Laura Strohmenger ◽  
Silvio Abati
Keyword(s):  
Lichen Planus ◽  
Oral Lichen Planus ◽  
Weighted Kappa ◽  
Mucous Membrane Pemphigoid ◽  
Histopathological Diagnosis ◽  
Severe Dysplasia ◽  
Oral Lesions ◽  
Oral Medicine ◽  
Squamous Papilloma ◽  
Oral Lichen

Background: Histopathological examination remains the gold standard for the diagnosis of oral mucosal lesions. To date little is known on the clinical–pathologic agreement for oral lesions diagnosed by oral medicine experts.  Objective: This retrospective study attempts to quantify the clinical–pathologic agreement for oral lesions diagnosed by oral medicine experts. Methods: Data were collected retrospectively from the medical records of all new oral medicine consultations. The clinical diagnosis provided by an oral medicine expert was compared to the histopathological diagnosis. Clinical–pathologic agreement was estimated as the percentage agreement and was measured using weighted Kappa. Results: The most common oral lesions were oral lichen planus (34.7%), traumatic fibroma (23.4%), squamous cell carcinoma (SCC) or severe dysplasia (6.7%), mucous membrane pemphigoid (MMP) (5.7%), leukoplakia (5.6%) and squamous papilloma (4.3%). The overall clinical–pathologic agreement for all lesions had a weighted kappa of 0.81 [95%CI 0.78% to 0.85%]. The concordance for the most common oral lesions in the study population was 90.2%, with a weighted kappa of 0.88 [95%CI 0.85% to 0.92%]. The clinical–pathologic agreement for SCC/severe dysplasia was 78.7%, for traumatic fibroma 91.4%, for leukoplakia 97.4%, for oral lichen planus 93.8%, for squamous papilloma 96.7% and for MMP 65%. Conclusions: The overall concordance between clinical and histopathological diagnosis for oral lesions was excellent. Dentists have the unique opportunity to refer patients to oral medicine experts for diagnosis and management of oral diseases. Given their expertise patients may require fewer visits for diagnostic purposes.

Assessment of IL-17 in Oral Lichen Planus and in Pemphigus Vulgaris

2019 ◽  
Vol 65 (1) ◽  
pp. 343-350
Author(s):  
Ibrahim El-Refai ◽  
Amira Maged ◽  
Dina El-Saady
Keyword(s):  
Lichen Planus ◽  
Oral Lichen Planus ◽  
Pemphigus Vulgaris ◽  
Oral Lichen

scholarly journals Lichen planus: Oral manifestations, differential diagnosis and treatment

2020 ◽  
Vol 36 (81) ◽  
pp. 1980-1994
Author(s):  
Marija Bradić-Vasić ◽  
Ana Pejčić ◽  
Milena Kostić ◽  
Ivan Minić ◽  
Radmila Obradović ◽  
...  
Keyword(s):  
Lichen Planus ◽  
Oral Lichen Planus ◽  
Skin Diseases ◽  
Precancerous Lesion ◽  
Pemphigus Vulgaris ◽  
Clinical History ◽  
Diagnosis And Treatment ◽  
Aged Patients ◽  
Mucous Membranes ◽  
Oral Lichen

Introduction: Some of the typical skin diseases, such as Pemphigus vulgaris, Pemphigoid mucosae oris, Erythema exudativum multiforme, Sclerodremia, Dermatitis herpetiformis-Duhring and Lichen planus, can cause swelling and irritation in mucous membranes of the oral cavity. Aim: The aim of the study was to precise diagnosis and treatment of oral Lichen planus manifestations. Methods: Analyzing the literature data and the experience of clinicians, the most common oral lichen planus manifestations were investigated. Results: This disease most commonly occurs in middle-aged patients (30-60 years) and is more common in women than in men. Oral Lichen planus is rarely seen in children. The disease presents in 0.5% to 2% of the population. Clinical history established the relation between oral Lichen planus and oral carcinoma, and therefore this disease should be considered a precancerous lesion. Conclusion: Dermatoses in the mouth are localized most often in the oral mucosa, both at the height of the occlusal line and in the mucous membrane of the retromolar area, but they can also occur in the mucous membranes of the tongue, the floor of the mouth and lips.

Coexistence of oral lichen planus and pemphigus vulgaris

2018 ◽  
Vol 22 (8) ◽  
pp. 2953-2955
Author(s):  
Kamran Balighi ◽  
HamidReza Mahmoudi ◽  
Soheil Tavakolpour ◽  
Maryam Daneshpazhooh
Keyword(s):  
Lichen Planus ◽  
Oral Lichen Planus ◽  
Pemphigus Vulgaris ◽  
Oral Lichen
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