Reflectance confocal microscopy as a new tool in thein vivoevaluation of desquamative gingivitis: patterns in mucous membrane pemphigoid, pemphigus vulgaris and oral lichen planus

2012 ◽  
Vol 168 (2) ◽  
pp. 257-264 ◽  
Author(s):  
S.S. Alessi ◽  
M.M.S. Nico ◽  
J.D. Fernandes ◽  
S.V. Lourenço
Keyword(s):  
Confocal Microscopy ◽  
Lichen Planus ◽  
Mucous Membrane ◽  
Oral Lichen Planus ◽  
Pemphigus Vulgaris ◽  
Reflectance Confocal Microscopy ◽  
Mucous Membrane Pemphigoid ◽  
Oral Lichen

scholarly journals Desquamative Gingivitis: Protocols, Procedures and Critical Issues

Proceedings ◽  
2019 ◽  
Vol 35 (1) ◽  
pp. 2
Author(s):  
Paola Carcieri
Keyword(s):  
Lichen Planus ◽  
Mucous Membrane ◽  
Plasma Cell ◽  
Oral Lichen Planus ◽  
Pemphigus Vulgaris ◽  
Mucous Membrane Pemphigoid ◽  
Critical Issues ◽  
Oral Lichen

Desquamative gingivitis (DG) isn’t a specific disorder; it simply represents the gingival manifestation associated with some heterogeneous mucocutaneous disorders, such as oral lichen planus (OLP), mucous membrane pemphigoid (MMP), pemphigus vulgaris (PV), plasma cell gingivitis (PCG) and few others. [...]

scholarly journals Immune-Mediated Desquamative Gingivitis and Optical Coherence Tomography Diagnostic Patterns: Clinical Implication from a Systematic Review

Diagnostics ◽  
2021 ◽  
Vol 11 (8) ◽  
pp. 1453
Author(s):  
Vera Panzarella ◽  
Alessia Bartolone ◽  
Vito Rodolico ◽  
Giorgia Capocasale ◽  
Laura Maniscalco ◽  
...  
Keyword(s):  
Systematic Review ◽  
Optical Coherence Tomography ◽  
Lichen Planus ◽  
Mucous Membrane ◽  
Oral Lichen Planus ◽  
Pemphigus Vulgaris ◽  
Mucous Membrane Pemphigoid ◽  
Optical Coherence ◽  
Immune Mediated ◽  
Oral Lichen

Desquamative Gingivitis (DG) comprises heterogeneous clinical manifestations of numerous immune-mediated muco-cutaneous diseases. Optical Coherence Tomography (OCT) has been proposed as a valuable diagnostic support even if, to date, there are no standardized OCT-diagnostic patterns applicable to DGs. A systematic review was performed to detect existing data on in vivo OCT diagnostic patterns of the most common immune-mediated DGs (i.e., pemphigus vulgaris, mucous membrane pemphigoid and oral lichen planus). It has been found that OCT exhibits specific patterns that address the diagnosis of DG by pemphigus vulgaris (i.e., intraepithelial unilocular blister, reduced epithelial thickness, presence of acantholytic cells in the blister) and by mucous membrane pemphigoid (i.e., subepithelial multilocular blister, presence of inflammatory infiltrate), but not by oral lichen planus. These patterns could offer an attractive diagnostic OCT framework to support the clinical preliminary assessment and monitoring of these complex pathological conditions.

In vivo reflectance confocal microscopy of oral lichen planus

2019 ◽  
Vol 58 (8) ◽  
pp. 940-945 ◽  
Author(s):  
Maria Contaldo ◽  
Dario Di Stasio ◽  
Massimo Petruzzi ◽  
Rosario Serpico ◽  
Alberta Lucchese
Keyword(s):  
Confocal Microscopy ◽  
Lichen Planus ◽  
Oral Lichen Planus ◽  
Reflectance Confocal Microscopy ◽  
Oral Lichen

Four cases of mucous membrane pemphigoid with clinical features of oral lichen planus

2015 ◽  
Vol 55 (6) ◽  
pp. 657-665 ◽  
Author(s):  
Aoi Fukuda ◽  
Akio Himejima ◽  
Daisuke Tsuruta ◽  
Hiroshi Koga ◽  
Bungo Ohyama ◽  
...  
Keyword(s):  
Lichen Planus ◽  
Mucous Membrane ◽  
Clinical Features ◽  
Oral Lichen Planus ◽  
Mucous Membrane Pemphigoid ◽  
Oral Lichen

Clinical–pathologic Agreement for Oral Lesions in an Oral Medicine Setting

2016 ◽  
Vol 2 (1) ◽  
pp. 1-10 ◽  
Author(s):  
Alessandro Villa ◽  
Francesco Nordio ◽  
Laura Strohmenger ◽  
Silvio Abati
Keyword(s):  
Lichen Planus ◽  
Oral Lichen Planus ◽  
Weighted Kappa ◽  
Mucous Membrane Pemphigoid ◽  
Histopathological Diagnosis ◽  
Severe Dysplasia ◽  
Oral Lesions ◽  
Oral Medicine ◽  
Squamous Papilloma ◽  
Oral Lichen

Background: Histopathological examination remains the gold standard for the diagnosis of oral mucosal lesions. To date little is known on the clinical–pathologic agreement for oral lesions diagnosed by oral medicine experts.  Objective: This retrospective study attempts to quantify the clinical–pathologic agreement for oral lesions diagnosed by oral medicine experts. Methods: Data were collected retrospectively from the medical records of all new oral medicine consultations. The clinical diagnosis provided by an oral medicine expert was compared to the histopathological diagnosis. Clinical–pathologic agreement was estimated as the percentage agreement and was measured using weighted Kappa. Results: The most common oral lesions were oral lichen planus (34.7%), traumatic fibroma (23.4%), squamous cell carcinoma (SCC) or severe dysplasia (6.7%), mucous membrane pemphigoid (MMP) (5.7%), leukoplakia (5.6%) and squamous papilloma (4.3%). The overall clinical–pathologic agreement for all lesions had a weighted kappa of 0.81 [95%CI 0.78% to 0.85%]. The concordance for the most common oral lesions in the study population was 90.2%, with a weighted kappa of 0.88 [95%CI 0.85% to 0.92%]. The clinical–pathologic agreement for SCC/severe dysplasia was 78.7%, for traumatic fibroma 91.4%, for leukoplakia 97.4%, for oral lichen planus 93.8%, for squamous papilloma 96.7% and for MMP 65%. Conclusions: The overall concordance between clinical and histopathological diagnosis for oral lesions was excellent. Dentists have the unique opportunity to refer patients to oral medicine experts for diagnosis and management of oral diseases. Given their expertise patients may require fewer visits for diagnostic purposes.

Assessment of IL-17 in Oral Lichen Planus and in Pemphigus Vulgaris

2019 ◽  
Vol 65 (1) ◽  
pp. 343-350
Author(s):  
Ibrahim El-Refai ◽  
Amira Maged ◽  
Dina El-Saady
Keyword(s):  
Lichen Planus ◽  
Oral Lichen Planus ◽  
Pemphigus Vulgaris ◽  
Oral Lichen
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