scholarly journals Immune-Mediated Desquamative Gingivitis and Optical Coherence Tomography Diagnostic Patterns: Clinical Implication from a Systematic Review

Diagnostics ◽  
2021 ◽  
Vol 11 (8) ◽  
pp. 1453
Author(s):  
Vera Panzarella ◽  
Alessia Bartolone ◽  
Vito Rodolico ◽  
Giorgia Capocasale ◽  
Laura Maniscalco ◽  
...  
Keyword(s):  
Systematic Review ◽  
Optical Coherence Tomography ◽  
Lichen Planus ◽  
Mucous Membrane ◽  
Oral Lichen Planus ◽  
Pemphigus Vulgaris ◽  
Mucous Membrane Pemphigoid ◽  
Optical Coherence ◽  
Immune Mediated ◽  
Oral Lichen

Desquamative Gingivitis (DG) comprises heterogeneous clinical manifestations of numerous immune-mediated muco-cutaneous diseases. Optical Coherence Tomography (OCT) has been proposed as a valuable diagnostic support even if, to date, there are no standardized OCT-diagnostic patterns applicable to DGs. A systematic review was performed to detect existing data on in vivo OCT diagnostic patterns of the most common immune-mediated DGs (i.e., pemphigus vulgaris, mucous membrane pemphigoid and oral lichen planus). It has been found that OCT exhibits specific patterns that address the diagnosis of DG by pemphigus vulgaris (i.e., intraepithelial unilocular blister, reduced epithelial thickness, presence of acantholytic cells in the blister) and by mucous membrane pemphigoid (i.e., subepithelial multilocular blister, presence of inflammatory infiltrate), but not by oral lichen planus. These patterns could offer an attractive diagnostic OCT framework to support the clinical preliminary assessment and monitoring of these complex pathological conditions.

scholarly journals Desquamative Gingivitis: Protocols, Procedures and Critical Issues

Proceedings ◽  
2019 ◽  
Vol 35 (1) ◽  
pp. 2
Author(s):  
Paola Carcieri
Keyword(s):  
Lichen Planus ◽  
Mucous Membrane ◽  
Plasma Cell ◽  
Oral Lichen Planus ◽  
Pemphigus Vulgaris ◽  
Mucous Membrane Pemphigoid ◽  
Critical Issues ◽  
Oral Lichen

Desquamative gingivitis (DG) isn’t a specific disorder; it simply represents the gingival manifestation associated with some heterogeneous mucocutaneous disorders, such as oral lichen planus (OLP), mucous membrane pemphigoid (MMP), pemphigus vulgaris (PV), plasma cell gingivitis (PCG) and few others. [...]

scholarly journals Dental Implant Rehabilitation in Patients Suffering from Mucocutaneous Diseases: A Systematic Review and Meta-Analysis

2018 ◽  
Vol 12 (1) ◽  
pp. 873-883 ◽  
Author(s):  
Parichehr Zarean ◽  
Paridokht Zarean ◽  
Negar Kanounisabet ◽  
Ahmad Moghareabed ◽  
Mansour Rismanchian ◽  
...  
Keyword(s):  
Risk Factors ◽  
Systematic Review ◽  
Systemic Lupus Erythematosus ◽  
Lichen Planus ◽  
Lupus Erythematosus ◽  
Oral Lichen Planus ◽  
Meta Analysis ◽  
Pemphigus Vulgaris ◽  
Systemic Lupus ◽  
Oral Lichen

Objective: Dental implantations are widely used for oral rehabilitation of edentulous patients. Despite high success rate, there are some risk factors that have been associated with failures. Oral mucocutaneous diseases are one of these risk factors for implant insertion due to the immunosuppressive therapy. There are limited studies that have dealt with the subject of dental implantology in oral mucosal disorders mainly with patients with oral lichenplanus, pemphigoid, pemphigus vulgaris, and systemic lupus erythematosus. In order to assess the result of implantations in such patients, we have reviewed the studies. Materials and Methods: We searched PubMed, Science Direct, and Cochrane databases for articles published from Jan 2000 to Dec 2017, using key search word “dental implants”, “oral lichen planus”, “pemphigoid”, “pemphigus vulgaris” and ”systemic lupus erythematosus”. Results: The random effects analysis result shows overall failure rates of 22% in patients with oral lichen planus. A systematic review revealed some failures that are not definitely related to these diseases. Conclusion: Due to the lack of adequate studies, a meta-analysis was only possible for oral lichen planus. Presently, there is no definite guideline regarding the placement of implant in patients suffering from mucocutaneous diseases; nevertheless, we should always consider that these patients are specific cases and need more attention in the first step of treatment and follow-ups. So there is a need to further clinical studies in order to evaluate more risk factors accurately and make a definitive conclusion.

Four cases of mucous membrane pemphigoid with clinical features of oral lichen planus

2015 ◽  
Vol 55 (6) ◽  
pp. 657-665 ◽  
Author(s):  
Aoi Fukuda ◽  
Akio Himejima ◽  
Daisuke Tsuruta ◽  
Hiroshi Koga ◽  
Bungo Ohyama ◽  
...  
Keyword(s):  
Lichen Planus ◽  
Mucous Membrane ◽  
Clinical Features ◽  
Oral Lichen Planus ◽  
Mucous Membrane Pemphigoid ◽  
Oral Lichen
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