scholarly journals Digital Twin Application for Model-Based DoE to Rapidly Identify Ideal Process Conditions for Space-Time Yield Optimization

Processes ◽  
2021 ◽  
Vol 9 (7) ◽  
pp. 1109
Author(s):  
Benjamin Bayer ◽  
Roger Dalmau Diaz ◽  
Michael Melcher ◽  
Gerald Striedner ◽  
Mark Duerkop

The fast exploration of a design space and identification of the best process conditions facilitating the highest space-time yield are of great interest for manufacturers. To obtain this information, depending on the design space, a large number of practical experiments must be performed, analyzed, and evaluated. To reduce this experimental effort and increase the process understanding, we evaluated a model-based design of experiments to rapidly identify the optimum process conditions in a design space maximizing space-time yield. From a small initial dataset, hybrid models were implemented and used as digital bioprocess twins, thus obtaining the recommended optimal experiment. In cases where these optimum conditions were not covered by existing data, the experiment was carried out and added to the initial data set, re-training the hybrid model. The procedure was repeated until the model gained certainty about the best process conditions, i.e., no new recommendations. To evaluate this workflow, we utilized different initial data sets and assessed their respective performances. The fastest approach for optimizing the space-time yield in a three-dimensional design space was found with five initial experiments. The digital twin gained certainty after four recommendations, leading to a significantly reduced experimental effort compared to other state-of-the-art approaches. This highlights the benefits of in silico design space exploration for accelerating knowledge-based bioprocess development, and reducing the number of hands-on experiments, time, energy, and raw materials.

2015 ◽  
Vol 2015 ◽  
pp. 1-20
Author(s):  
Gongyu Wang ◽  
Greg Stitt ◽  
Herman Lam ◽  
Alan George

Field-programmable gate arrays (FPGAs) provide a promising technology that can improve performance of many high-performance computing and embedded applications. However, unlike software design tools, the relatively immature state of FPGA tools significantly limits productivity and consequently prevents widespread adoption of the technology. For example, the lengthy design-translate-execute (DTE) process often must be iterated to meet the application requirements. Previous works have enabled model-based, design-space exploration to reduce DTE iterations but are limited by a lack of accurate model-based prediction of key design parameters, the most important of which is clock frequency. In this paper, we present a core-level modeling and design (CMD) methodology that enables modeling of FPGA applications at an abstract level and yet produces accurate predictions of parameters such as clock frequency, resource utilization (i.e., area), and latency. We evaluate CMD’s prediction methods using several high-performance DSP applications on various families of FPGAs and show an average clock-frequency prediction error of 3.6%, with a worst-case error of 20.4%, compared to the best of existing high-level prediction methods, 13.9% average error with 48.2% worst-case error. We also demonstrate how such prediction enables accurate design-space exploration without coding in a hardware-description language (HDL), significantly reducing the total design time.


Author(s):  
Nicolas Albarello ◽  
Jean-Baptiste Welcomme

The design of systems architectures often involve a combinatorial design-space made of technological and architectural choices. A complete or large exploration of this design space requires the use of a method to generate and evaluate design alternatives. This paper proposes an innovative approach for the design-space exploration of systems architectures. The SAMOA (System Architecture Model-based OptimizAtion) tool associated to the method is also introduced. The method permits to create a large number of various system architectures combining a set of possible components to address given system functions. The method relies on models that are used to represent the problem and the solutions and to evaluate architecture performances. An algorithm first synthesizes design alternatives (a physical architecture associated to a functional allocation) based on the functional architecture of the system, the system interfaces, a library of available components and user-defined design rules. Chains of components are sequentially added to an initially empty architecture until all functions are fulfilled. The design rules permit to guarantee the viability and validity of the chains of components and, consequently, of the generated architectures. The design space exploration is then performed in a smart way through the use of an evolutionary algorithm, the evolution mechanisms of which are specific to system architecting. Evaluation modules permit to assess the performances of alternatives based on the structure of the architecture model and the data embedded in the component models. These performances are used to select the best generated architectures considering constraints and quality metrics. This selection is based on the Pareto-dominance-based NSGA-II algorithm or, alternatively, on an interactive preference-based algorithm. Iterating over this evolution-evaluation-selection process permits to increase the quality of solutions and, thus, to highlight the regions of interest of the design-space which can be used as a base for further manual investigations. By using this method, the system designers have a larger confidence in the optimality of the adopted architecture than using a classical derivative approach as many more solutions are evaluated. Also, the method permits to quickly evaluate the trade-offs between the different considered criteria. Finally, the method can also be used to evaluate the impact of a technology on the system performances not only by a substituting a technology by another but also by adapting the architecture of the system.


2015 ◽  
Vol 23 (5) ◽  
pp. 1501-1513 ◽  
Author(s):  
Sergi Abadal ◽  
Mario Iannazzo ◽  
Mario Nemirovsky ◽  
Albert Cabellos-Aparicio ◽  
Heekwan Lee ◽  
...  

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