scholarly journals Finite Element Analysis for Biodegradable Dissolving Microneedle Materials on Skin Puncture and Mechanical Performance Evaluation

Polymers ◽  
2021 ◽  
Vol 13 (18) ◽  
pp. 3043
Author(s):  
Qinying Yan ◽  
Jiaqi Weng ◽  
Shulin Shen ◽  
Yan Wang ◽  
Min Fang ◽  
...  
Keyword(s):  
Mechanical Performance ◽  
Simulation Analysis ◽  
Experimental Tests ◽  
Solid Content ◽  
Research Progress ◽  
Comsol Multiphysics ◽  
Breaking Force ◽  
Element Analysis ◽  
Dissolving Microneedles ◽  
Solids Content

In this study, a micro-molding technology was used to prepare the microneedles (MNs), while a texture analyzer was used to measure its Young’s modulus, Poisson’s ratio and compression breaking force, to evaluate whether the MNs can penetrate the skin. The effects of different materials were characterized by their ability to withstand stresses using the Structural Mechanics Module of COMSOL Multiphysics. Carboxymethylcellulose (CMC) was chosen as the needle formulation material with varying quantities of polyvinyl pyrrolidone (PVP), polyvinyl alcohol (PVA) and hyaluronic acid (HA) to adjust the viscosity, brittleness, hardness and solubility of the material. The results of both the experimental tests and the predictions indicated that the hardest tip material had a solids content of 15% (w/w ) with a 1:2 (w/w) CMC: HA ratio. Furthermore, it was shown that a solid content of 10% (w/w) with a 1:5 (w/w) CMC: PVA ratio is suitable for making patches. The correlation between the mechanical properties and the different materials was found using the simulation analysis as well as the force required for different dissolving microneedles (DMNs) to penetrate the skin, which significantly promoted the research progress of microneedle transdermal drug delivery.

Analysis of the crashworthiness design and collision dynamics of a subway train

2019 ◽  
Vol 234 (10) ◽  
pp. 1117-1128
Author(s):  
Suchao Xie ◽  
Xuanjin Du ◽  
Hui Zhou ◽  
Da Wang ◽  
Zhejun Feng
Keyword(s):  
Finite Element ◽  
Energy Absorption ◽  
Mechanical Performance ◽  
Simulation Analysis ◽  
Element Model ◽  
Collision Dynamics ◽  
Element Analysis ◽  
Static Compression ◽  
Subway Train ◽  
Energy Absorbing

In this study, the crashworthiness of a subway train was assessed by establishing a finite element model for the first three carriages of the train and the track using the Hypermesh software. By utilising the *MAT_HONEYCOMB material model, a honeycomb in an anti-climbing energy-absorbing device was simulated. Moreover, the process of a subway train – travelling at a speed of 25 km/h – colliding with another identical train in a stationary and non-braking state was simulated by employing the finite element analysis software Hypermesh and LS-DYNA. The process of simulation analysis was divided into two parts: (1) analysis of the anti-climbing energy-absorbing devices under static compression for the investigation of energy absorption and (2) collision analysis of the whole train. The contributions of the proposed energy-absorbing structure – at the end of driver’s cab, the coupler and draft gears on each section – to the overall energy absorption in a train collision were calculated. Furthermore, based on the EN15227 standard, the crashworthiness of the train with respect to the survival space for occupants, train acceleration and uplift of wheels relative to the track was evaluated. The coupler of the first carriage fails in a collision at 25 km/h, and the coupler and draft gear are the main energy-absorbing devices. *MAT_HONEYCOMB was used to define the honeycomb materials in anti-climbing energy-absorbing devices and could simulate the mechanical performance thereof. The crashworthiness of the train meets the relevant standard requirements.

scholarly journals Modal Analysis of a Single-Structure Multiaxis MEMS Gyroscope

2016 ◽  
Vol 2016 ◽  
pp. 1-8 ◽  
Author(s):  
Muhammad Ali Shah ◽  
Faisal Iqbal ◽  
Ibrar Ali Shah ◽  
Byeungleul Lee
Keyword(s):  
Simulation Analysis ◽  
Comsol Multiphysics ◽  
Stress Effect ◽  
Element Analysis ◽  
Mems Gyroscope ◽  
Vacuum Level ◽  
Driving Mode ◽  
Single Structure ◽  
Angular Velocities ◽  
The Cost

This paper reports on designing a single-structure triaxes MEMS capacitive gyroscope which is capable of measuring the three angular velocities on a single drive. A Z-shaped beam for the support of folded coupling spring has been applied to suppress the unwanted mode and decrease the stress effect at the spring ends. The unique coupling spring has changed the driving motion, due to which slide film damping in the driving mode has been reduced. This reduction can lead to higher performance of the sensor with less requirements on vacuum level which decreases the cost of fabrication. Simulation analysis has been performed in COMSOL Multiphysics and Matlab Simulink to finalize the design for fabrication. After finite element analysis, the driving, x-sensing, z-sensing, and y-sensing are, respectively, found to be 13.30 KHz, 13.40 KHz, 13.47 KHz, and 13.51 KHz.

scholarly journals Developing polymer composite-based leaf spring systems for automotive industry

2018 ◽  
Vol 25 (6) ◽  
pp. 1167-1176 ◽  
Author(s):  
Nahit Oztoprak ◽  
Mehmet Deniz Gunes ◽  
Metin Tanoglu ◽  
Engin Aktas ◽  
Oguz Ozgur Egilmez ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Finite Element ◽  
Mechanical Performance ◽  
Experimental Tests ◽  
Polymer Materials ◽  
Leaf Spring ◽  
Element Analysis ◽  
Reinforced Polymer ◽  
Light Commercial Vehicle ◽  
The Finite Element Analysis

AbstractComposite-based mono-leaf spring systems were designed and manufactured to replace existing mono-leaf metal leaf spring in a light commercial vehicle. In this study, experimentally obtained mechanical properties of different fiber-reinforced polymer materials are presented first, followed by the description of the finite element analytical model created in Abaqus 6.12-1 (Dassault Systemes Simulia Corp., RI, US) using the obtained properties. The results from the finite element analysis are presented next and compared with actual size experimental tests conducted on manufactured prototypes. The results demonstrated that the reinforcement type and orientation dramatically influenced the spring rate. The prototypes showed significant weight reduction of about 80% with improved mechanical properties. The hybrid composite systems can be utilized for composite-based leaf springs with considerable mechanical performance.

scholarly journals Research on Vibration Characteristics of Piezoelectric Ceramic Atomizer Based on ANSYS

2019 ◽  
Vol 118 ◽  
pp. 02043
Author(s):  
Yan Chen ◽  
Chunyan Ma ◽  
Zaihe Shen ◽  
Rui Chen
Keyword(s):  
Resonant Frequency ◽  
Piezoelectric Ceramic ◽  
Vibration Mode ◽  
Simulation Analysis ◽  
Experimental Tests ◽  
Vibration Characteristics ◽  
Response Analysis ◽  
Element Analysis ◽  
Piezoelectric Coupling ◽  
Harmonic Response Analysis

In the design and application of ultrasonic atomizer, the resonant frequency and vibration mode of piezoelectric transducer have an effect on the working state and atomization effect of the atomizer. In order to deeply study the piezoelectric ceramic ultrasonic atomizer Vibration characteristics, piezoelectric coupling simulation analysis was performed by ANSYS software, multi-order vibration mode of piezoelectric ceramic atomization sheet obtained by modal analysis method, combined with harmonic response analysis to obtain resonant frequency of piezoelectric ceramic ultrasonic atomization sheet, and analysis the influence of the main size of the atomized sheet on the vibration mode. According to theoretical analysis and experimental tests, the effectiveness of the finite element analysis can be verified, and then provide a theoretical basis for the study of ultrasonic atomizers.

Effects of Fission Profiles on the Performance of a U-10Mo Fuel Plate

2019 ◽  
Author(s):  
Hee Seok Roh ◽  
Walid Mohamed ◽  
Hakan Ozaltun
Keyword(s):  
High Performance ◽  
Mechanical Performance ◽  
Experimental Tests ◽  
Operating Conditions ◽  
Fuel Performance ◽  
Element Analysis ◽  
Actual Use ◽  
Enriched Uranium ◽  
Performance Research ◽  
Plate Geometry

Abstract In order to convert the high-performance research reactors from High Enriched Uranium (HEU) to Low Enriched Uranium (LEU) fuel, U-Mo alloy-based fuels in monolithic form have been proposed. These plate-type fuels consist of a high density and low enriched uranium (LEU) foil coated with a diffusion barrier and encapsulated with the aluminum cladding. The performance of the fuel plate has been evaluated by many studies through experimental tests and numerical analyses. When evaluating the performance of a fuel, it is expensive and time-consuming to consider a variation of several parameters, such as fuel plate geometry, material properties, and operating conditions. Fission profile is a critical component of the fuel performance analysis, causing swelling and creep deformation of the fuel plate. Therefore, it can directly affect the stress and strain distributions over the fuel plate. This study aims at investigating the effect of different fission profiles on the thermo-mechanical performance of the fuel plate by finite element analysis. To investigate the effect of fission profile on fuel performance, several different fission profiles were generated and analyzed. The fission profiles were generated based on actual use.

scholarly journals 3D Printed Hierarchical Honeycombs with Carbon Fiber and Carbon Nanotube Reinforced Acrylonitrile Butadiene Styrene

2021 ◽  
Vol 5 (2) ◽  
pp. 62
Author(s):  
Michel Theodor Mansour ◽  
Konstantinos Tsongas ◽  
Dimitrios Tzetzis
Keyword(s):  
Carbon Fibers ◽  
Mechanical Performance ◽  
Acrylonitrile Butadiene Styrene ◽  
Experimental Tests ◽  
Fused Filament Fabrication ◽  
Element Analysis ◽  
Compression Performance ◽  
Honeycomb Structures ◽  
3D Printed ◽  
Butadiene Styrene

The mechanical properties of Fused Filament Fabrication (FFF) 3D printed specimens of acrylonitrile butadiene styrene (ABS), ABS reinforced with carbon fibers (ABS/CFs) and ABS reinforced with carbon nanotubes (ABS/CNTs) are investigated in this paper using various experimental tests. In particular, the mechanical performance of the fabricated specimens was determined by conducting compression and cyclic compression testing, as well as nanoindentation tests. In addition, the design and the manufacturing of hierarchical honeycomb structures are presented using the materials under study. The 3D printed honeycomb structures were examined by uniaxial compressive tests to review the mechanical behavior of such cellular structures. The compressive performance of the hierarchical honeycomb structures was also evaluated with finite element analysis (FEA) in order to extract the stress-strain response of these structures. The results revealed that the 2nd order hierarchy displayed increased stiffness and strength as compared with the 0th and the 1st hierarchies. Furthermore, the addition of carbon fibers in the ABS matrix improved the stiffness, the strength and the hardness of the FFF printed specimens as well as the compression performance of the honeycomb structures.

Effect of Experimental Conditions on Estimation of Compressive Stiffness of Spinal Cages

2013 ◽  
Author(s):  
Yoon Hyuk Kim ◽  
Dae Kyung Choi ◽  
Kyungsoo Kim
Keyword(s):  
Mechanical Performance ◽  
Experimental Tests ◽  
Mechanical Tests ◽  
Standard Test ◽  
Experimental Conditions ◽  
Element Analysis ◽  
Compressive Stiffness ◽  
Reinforced Polymer

Recently, novel polymers including polyetheretherketone (PEEK) and carbon fiber reinforced polymer (CFRP) have been used for spinal implants. Because the in vitro experimental test uses metal blocks with different material properties from those of polymer cages in standard test protocols for prediction of the mechanical performance, it is necessary to analyze the influence of various experimental conditions, such as the material of the blocks. In this study, the compressive stiffness of spinal cages was estimated for different materials (PEEK, CFRP, and titanium) and shapes (open and closed) under simulations of the mechanical experimental tests and the in vivo situation using finite element analysis. The stiffness percentages of the open cage, when the stiffness in Case 1 was assumed 100%, were changed from 37%, 57% and 67% to 301%, 440% and 499% in the PEEK, CFRP and titanium materials, respectively by loading conditions. The stiffness was affected by shapes of cage as well as experimental conditions such as the load application method or fixation block. Hence, it may be necessary to consider the experimental conditions during in vitro mechanical tests for the stiffness estimation of spinal cages made of novel polymers to obtain results relevant for an in vivo situation.

Supercritical Water Gasification of Scenedesmus Dimorphus µ-algae

2017 ◽  
Vol 15 (4) ◽  
Author(s):  
A. Molino ◽  
T. Marino ◽  
V. Larocca ◽  
P. Casella ◽  
J. Rimauro ◽  
...  
Keyword(s):  
Supercritical Water ◽  
Energy Demand ◽  
Energy Recovery ◽  
Experimental Tests ◽  
Total Solid ◽  
Solid Content ◽  
Total Solid Content ◽  
Syngas Production ◽  
Scenedesmus Dimorphus ◽  
Solids Content

Abstract The aim of the paper is based on the experimental tests of Gasification in supercritical water for humid biomass, Scenedesmus dimorphus. In this work, experimental tests were carried out in order to understand the main parameters of the SCWG process and their influence varying the total solids content, GGE and CGE gas yield and energy recovery. Based on experimental test and considering literature data about energy demand for microalgae growth and energy required for SCWG process it was possible to evaluate that with minimum total solid content necessary for setting-up a self-sustainable process considering the only energy recovery from the condensation of the water outlet the process. At the same time these simulation were repeated considering of use the enthalpy of water in SCW condition for turbine expansion instead heat recovery obtained not only syngas production usable for biofuels synthesis but also power production.

Application of Coupled Structural Acoustic Analysis and Sensitivity Calculations to a Tire Noise Problem

2012 ◽  
Vol 40 (1) ◽  
pp. 25-41 ◽  
Author(s):  
H. M. R. Aboutorabi ◽  
L. Kung
Keyword(s):  
Performance Improvement ◽  
Acoustic Analysis ◽  
Simulation Analysis ◽  
Analysis Method ◽  
Vehicle Manufacturer ◽  
Element Analysis ◽  
Equipment Manufacturer ◽  
Tire Noise ◽  
Fea Modeling ◽  
Testing Instruments

Abstract REFERENCE: H. M. R. Aboutorabi and L. Kung, “Application of Coupled Structural Acoustic Analysis and Sensitivity Calculations to a Tire Noise Problem,” Tire Science and Technology, TSTCA, Vol. 40, No. 1, January – March 2012, pp. 25–41. ABSTRACT: Tire qualification for an original equipment (OE) program consists of several rounds of submissions by the tire manufacturer for evaluation by the vehicle manufacturer. Tires are evaluated both subjectively, where the tire performance is rated by an expert driver, and objectively, where sensors and testing instruments are used to measure the tire performance. At the end of each round of testing the evaluation results are shared and requirements for performance improvement for the next round are communicated with the tire manufacturer. As building and testing is both expensive and time consuming predictive modeling and simulation analysis that can be applied to the performance of the tire is of great interest and value. This paper presents an application of finite element analysis (FEA) modeling along with experimental verification to solve tire noise objections at certain frequencies raised by an original equipment manufacturer (OEM) account. Coupled structural-acoustic analysis method was used to find modal characteristics of the tire at the objectionable frequencies. Sensitivity calculations were then carried out to evaluate the strength of contribution from each tire component to the identified modes. Based on these findings changes to the construction were proposed and implemented that addressed the noise issue.

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