scholarly journals Performance and Health Benefits of Dietary Nitrate Supplementation in Older Adults: A Systematic Review

Nutrients ◽  
2017 ◽  
Vol 9 (11) ◽  
pp. 1171 ◽  
Author(s):  
Luke Stanaway ◽  
Kay Rutherfurd-Markwick ◽  
Rachel Page ◽  
Ajmol Ali
2012 ◽  
Vol 1 (6) ◽  
pp. 402-410 ◽  
Author(s):  
Amanda K. Hall ◽  
Enmanuel Chavarria ◽  
Vasana Maneeratana ◽  
Beth H. Chaney ◽  
Jay M. Bernhardt

Nitric Oxide ◽  
2021 ◽  
Vol 113-114 ◽  
pp. 13-22
Author(s):  
Yayu He ◽  
Jinshu Liu ◽  
Hongwei Cai ◽  
Jun Zhang ◽  
Jiang Yi ◽  
...  

Nitric Oxide ◽  
2016 ◽  
Vol 53 ◽  
pp. 65-76 ◽  
Author(s):  
Mehdi Pawlak-Chaouch ◽  
Julien Boissière ◽  
François X. Gamelin ◽  
Grégory Cuvelier ◽  
Serge Berthoin ◽  
...  

Nutrients ◽  
2020 ◽  
Vol 12 (10) ◽  
pp. 3022
Author(s):  
Ángel Lago-Rodríguez ◽  
Raúl Domínguez ◽  
Juan José Ramos-Álvarez ◽  
Francisco Miguel Tobal ◽  
Pablo Jodra ◽  
...  

Dietary nitrate (NO3−) supplementation, which can enhance performance in exercise settings involving repeated high-intensity efforts, has been linked to improved skeletal muscle contractile function. Although muscular strength is an important component of explosive movements and sport-specific skills, few studies have quantified indices of muscular strength following NO3− supplementation, particularly isokinetic assessments at different angular velocities. We performed a systematic review and meta-analysis to determine whether dietary NO3− supplementation improves peak torque, as assessed by the gold standard method of isokinetic dynamometry, and if this effect was linked to the angular velocity imposed during the assessment. Dialnet, Directory of Open Access Journals, MEDLINE, PubMed, SciELO, Scopus, and SPORTDiscus were searched for articles using the following search strategy: (nitrate OR beet*) AND (supplement* OR nutr* OR diet*) AND (isokinetic OR strength OR “resistance exercise” OR “resistance training” OR “muscular power”). The meta-analysis of data from 5 studies with 60 participants revealed an overall effect size of −0.01 for the effect of nitrate supplementation on isokinetic peak torque, whereas trivial effect sizes ranging from −0.11 to 0.16 were observed for independent velocity-specific (90°/s, 180°/s, 270°/s, and 360°/s) isokinetic peak torque. Four of the five studies indicated that dietary NO3− supplementation is not likely to influence voluntary knee extensor isokinetic torque across a variety of angular velocities. These results suggest that NO3− supplementation does not influence isokinetic peak torque, but further work is required to elucidate the potential of NO3− supplementation to influence other indices of muscular strength, given the dearth of experimental evidence on this topic.


Nutrients ◽  
2020 ◽  
Vol 12 (6) ◽  
pp. 1796 ◽  
Author(s):  
Jorge Lorenzo Calvo ◽  
Francesca Alorda-Capo ◽  
Helios Pareja-Galeano ◽  
Sergio L. Jiménez

Endurance can be defined as the capacity to maintain one’s velocity or power output for the longest possible time. Maintaining such activity can lead to the onset of fatigue. Dietary nitrate supplementation produces an ergogenic effect due to the improvement of mitochondrial oxygen efficiency through a reduction in the oxygen cost of exercise that increases vasodilation and blood flow to the skeletal muscle in recreationally active subjects. However, the effects of dietary nitrate supplementation on well-trained endurance athletes remain unclear; such supplementation could affect more performance areas. In the present study, a systematic review of the literature was conducted to clarify the use and effects of nitrate as a dietary supplement in endurance athletes trained in cyclic sports (repetitive movement sports). A systematic search was carried out following the Preferred Reporting Items for Systematic Review and Meta-Analyses (PRISMA) guidelines in the databases of SCOPUS, Web of Science (WOS), Medline (PubMed), and Sport Discus from 1 January 2010 to 30 November 2019. Twenty-seven studies were included in the study. The methodological quality of the articles was assessed using the McMaster Critical Review Form. Statistically significant ergogenic results were obtained in 8 (29.63%) of the 27 studies investigated, with significant results obtained for cardiorespiratory parameters and performance measures. Improvement in exercise tolerance was obtained, which could help with exhaustion over time, while the improvement in exercise economics was not as clear. Additionally, the dose necessary for this ergogenic effect seems to have a direct relationship with the physical condition of the athlete. The acute dose is around 6–12.4 mmol/day of nitrate administered 2–3 h before the activity, with the same amount given as a chronic dose over 6–15 days. Further studies are required to understand the factors that affect the potential ergogenic impacts of nitrate on athletic performance among endurance athletes.


2021 ◽  
Vol 8 (1) ◽  
pp. e000948
Author(s):  
Abdullah S Alsulayyim ◽  
Ali M Alasmari ◽  
Saeed M Alghamdi ◽  
Michael I Polkey ◽  
Nicholas S Hopkinson

BackgroundDietary nitrate supplementation, usually in the form of beetroot juice, may improve exercise performance and endothelial function. We undertook a systematic review and meta-analysis to establish whether this approach has beneficial effects in people with respiratory disease.MethodsA systematic search of records up to March 2021 was performed on PubMed, CINAHL, MEDLINE (Ovid), Cochrane and Embase to retrieve clinical trials that evaluated the efficacy of dietary nitrate supplementation on cardiovascular parameters and exercise capacity in chronic respiratory conditions. Two authors independently screened titles, abstracts and full texts of potential studies and performed the data extraction.ResultsAfter full-text review of 67 papers, eleven (two randomised controlled trials and nine crossover trials) involving 282 participants met the inclusion criteria. Three were single dose; seven short term; and one, the largest (n=122), done in the context of pulmonary rehabilitation. Pooled analysis showed that dietary nitrate supplementation reduced systolic blood pressure (BP), diastolic BP and mean arterial pressure (mean difference (95% CI), −3.39 mm Hg (−6.79 to 0.01); p=0.05 and –2.20 mm Hg (−4.36 to −0.03); p=0.05 and −4.40 mm Hg (−7.49 to −1.30); p=0.005, respectively). It was associated with increased walk distance in the context of pulmonary rehabilitation (standardised mean difference (95% CI), 0.47 (0.11 to 0.83), p=0.01), but no effect was identified in short-term studies (0.08 (−0.32 to 0.49).ConclusionDietary nitrate supplementation may have a beneficial effect on BP and augment the effect of pulmonary rehabilitation on exercise capacity. Short-term studies do not suggest a consistent benefit on exercise capacity.PROSPERO registration numberCRD42019130123.


2013 ◽  
Vol 304 (2) ◽  
pp. R73-R83 ◽  
Author(s):  
James Kelly ◽  
Jonathan Fulford ◽  
Anni Vanhatalo ◽  
Jamie R. Blackwell ◽  
Olivia French ◽  
...  

Dietary nitrate (NO3−) supplementation has been shown to reduce resting blood pressure and alter the physiological response to exercise in young adults. We investigated whether these effects might also be evident in older adults. In a double-blind, randomized, crossover study, 12 healthy, older (60–70 yr) adults supplemented their diet for 3 days with either nitrate-rich concentrated beetroot juice (BR; 2 × 70 ml/day, ∼9.6 mmol/day NO3−) or a nitrate-depleted beetroot juice placebo (PL; 2 × 70 ml/day, ∼0.01 mmol/day NO3−). Before and after the intervention periods, resting blood pressure and plasma [nitrite] were measured, and subjects completed a battery of physiological and cognitive tests. Nitrate supplementation significantly increased plasma [nitrite] and reduced resting systolic (BR: 115 ± 9 vs. PL: 120 ± 6 mmHg; P < 0.05) and diastolic (BR: 70 ± 5 vs. PL: 73 ± 5 mmHg; P < 0.05) blood pressure. Nitrate supplementation resulted in a speeding of the V̇o2 mean response time (BR: 25 ± 7 vs. PL: 28 ± 7 s; P < 0.05) in the transition from standing rest to treadmill walking, although in contrast to our hypothesis, the O2 cost of exercise remained unchanged. Functional capacity (6-min walk test), the muscle metabolic response to low-intensity exercise, brain metabolite concentrations, and cognitive function were also not altered. Dietary nitrate supplementation reduced resting blood pressure and improved V̇o2 kinetics during treadmill walking in healthy older adults but did not improve walking or cognitive performance. These results may have implications for the enhancement of cardiovascular health in older age.


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