Effect of dietary nitrate supplementation on metabolic rate during rest and exercise in human: A systematic review and a meta-analysis

Nitric Oxide ◽  
2016 ◽  
Vol 53 ◽  
pp. 65-76 ◽  
Author(s):  
Mehdi Pawlak-Chaouch ◽  
Julien Boissière ◽  
François X. Gamelin ◽  
Grégory Cuvelier ◽  
Serge Berthoin ◽  
...  
Keyword(s):  
Systematic Review ◽  
Metabolic Rate ◽  
Meta Analysis ◽  
Dietary Nitrate ◽  
Nitrate Supplementation ◽  
Rest And Exercise

scholarly journals The Effect of Dietary Nitrate Supplementation on Isokinetic Torque in Adults: A Systematic Review and Meta-Analysis

Nutrients ◽  
2020 ◽  
Vol 12 (10) ◽  
pp. 3022
Author(s):  
Ángel Lago-Rodríguez ◽  
Raúl Domínguez ◽  
Juan José Ramos-Álvarez ◽  
Francisco Miguel Tobal ◽  
Pablo Jodra ◽  
...  
Keyword(s):  
Systematic Review ◽  
Muscular Strength ◽  
Meta Analysis ◽  
Peak Torque ◽  
Gold Standard Method ◽  
Dietary Nitrate ◽  
Angular Velocities ◽  
Isokinetic Torque ◽  
Nitrate Supplementation ◽  
Isokinetic Peak Torque

Dietary nitrate (NO3−) supplementation, which can enhance performance in exercise settings involving repeated high-intensity efforts, has been linked to improved skeletal muscle contractile function. Although muscular strength is an important component of explosive movements and sport-specific skills, few studies have quantified indices of muscular strength following NO3− supplementation, particularly isokinetic assessments at different angular velocities. We performed a systematic review and meta-analysis to determine whether dietary NO3− supplementation improves peak torque, as assessed by the gold standard method of isokinetic dynamometry, and if this effect was linked to the angular velocity imposed during the assessment. Dialnet, Directory of Open Access Journals, MEDLINE, PubMed, SciELO, Scopus, and SPORTDiscus were searched for articles using the following search strategy: (nitrate OR beet*) AND (supplement* OR nutr* OR diet*) AND (isokinetic OR strength OR “resistance exercise” OR “resistance training” OR “muscular power”). The meta-analysis of data from 5 studies with 60 participants revealed an overall effect size of −0.01 for the effect of nitrate supplementation on isokinetic peak torque, whereas trivial effect sizes ranging from −0.11 to 0.16 were observed for independent velocity-specific (90°/s, 180°/s, 270°/s, and 360°/s) isokinetic peak torque. Four of the five studies indicated that dietary NO3− supplementation is not likely to influence voluntary knee extensor isokinetic torque across a variety of angular velocities. These results suggest that NO3− supplementation does not influence isokinetic peak torque, but further work is required to elucidate the potential of NO3− supplementation to influence other indices of muscular strength, given the dearth of experimental evidence on this topic.

scholarly journals Impact of dietary nitrate supplementation on exercise capacity and cardiovascular parameters in chronic respiratory disease: a systematic review and meta-analysis

2021 ◽  
Vol 8 (1) ◽  
pp. e000948
Author(s):  
Abdullah S Alsulayyim ◽  
Ali M Alasmari ◽  
Saeed M Alghamdi ◽  
Michael I Polkey ◽  
Nicholas S Hopkinson
Keyword(s):  
Systematic Review ◽  
Respiratory Disease ◽  
Exercise Capacity ◽  
Pulmonary Rehabilitation ◽  
Meta Analysis ◽  
Mean Difference ◽  
Short Term ◽  
Cardiovascular Parameters ◽  
Dietary Nitrate ◽  
Nitrate Supplementation

BackgroundDietary nitrate supplementation, usually in the form of beetroot juice, may improve exercise performance and endothelial function. We undertook a systematic review and meta-analysis to establish whether this approach has beneficial effects in people with respiratory disease.MethodsA systematic search of records up to March 2021 was performed on PubMed, CINAHL, MEDLINE (Ovid), Cochrane and Embase to retrieve clinical trials that evaluated the efficacy of dietary nitrate supplementation on cardiovascular parameters and exercise capacity in chronic respiratory conditions. Two authors independently screened titles, abstracts and full texts of potential studies and performed the data extraction.ResultsAfter full-text review of 67 papers, eleven (two randomised controlled trials and nine crossover trials) involving 282 participants met the inclusion criteria. Three were single dose; seven short term; and one, the largest (n=122), done in the context of pulmonary rehabilitation. Pooled analysis showed that dietary nitrate supplementation reduced systolic blood pressure (BP), diastolic BP and mean arterial pressure (mean difference (95% CI), −3.39 mm Hg (−6.79 to 0.01); p=0.05 and –2.20 mm Hg (−4.36 to −0.03); p=0.05 and −4.40 mm Hg (−7.49 to −1.30); p=0.005, respectively). It was associated with increased walk distance in the context of pulmonary rehabilitation (standardised mean difference (95% CI), 0.47 (0.11 to 0.83), p=0.01), but no effect was identified in short-term studies (0.08 (−0.32 to 0.49).ConclusionDietary nitrate supplementation may have a beneficial effect on BP and augment the effect of pulmonary rehabilitation on exercise capacity. Short-term studies do not suggest a consistent benefit on exercise capacity.PROSPERO registration numberCRD42019130123.

scholarly journals The Effect of Beetroot Ingestion on High-Intensity Interval Training: A Systematic Review and Meta-Analysis

Nutrients ◽  
2021 ◽  
Vol 13 (11) ◽  
pp. 3674
Author(s):  
Tak Hiong Wong ◽  
Alexiaa Sim ◽  
Stephen F. Burns
Keyword(s):  
Systematic Review ◽  
Power Output ◽  
High Intensity ◽  
Meta Analysis ◽  
Interval Training ◽  
High Intensity Interval Training ◽  
Mean Power ◽  
Nitrate Supplementation ◽  
High Intensity Interval ◽  
Mean Power Output

Dietary nitrate supplementation has shown promising ergogenic effects on endurance exercise. However, at present there is no systematic analysis evaluating the effects of acute or chronic nitrate supplementation on performance measures during high-intensity interval training (HIIT) and sprint interval training (SIT). The main aim of this systematic review and meta-analysis was to evaluate the evidence for supplementation of dietary beetroot—a common source of nitrate—to improve peak and mean power output during HIIT and SIT. A systematic literature search was carried out following PRISMA guidelines and the PICOS framework within the following databases: PubMed, ProQuest, ScienceDirect, and SPORTDiscus. Search terms used were: ((nitrate OR nitrite OR beetroot) AND (HIIT or high intensity or sprint interval or SIT) AND (performance)). A total of 17 studies were included and reviewed independently. Seven studies applied an acute supplementation strategy and ten studies applied chronic supplementation. The standardised mean difference for mean power output showed an overall trivial, non-significant effect in favour of placebo (Hedges’ g = −0.05, 95% CI −0.32 to 0.21, Z = 0.39, p = 0.69). The standardised mean difference for peak power output showed a trivial, non-significant effect in favour of the beetroot juice intervention (Hedges’ g = 0.08, 95% CI -0.14 to 0.30, Z = 0.72, p = 0.47). The present meta-analysis showed trivial statistical heterogeneity in power output, but the variation in the exercise protocols, nitrate dosage, type of beetroot products, supplementation strategy, and duration among studies restricted a firm conclusion of the effect of beetroot supplementation on HIIT performance. Our findings suggest that beetroot supplementation offers no significant improvement to peak or mean power output during HIIT or SIT. Future research could further examine the ergogenic potential by optimising the beetroot supplementation strategy in terms of dosage, timing, and type of beetroot product. The potential combined effect of other ingredients in the beetroot products should not be undermined. Finally, a chronic supplementation protocol with a higher beetroot dosage (>12.9 mmol/day for 6 days) is recommended for future HIIT and SIT study.

scholarly journals The effect of exercise interventions on resting metabolic rate: A systematic review and meta-analysis

2020 ◽  
Vol 38 (14) ◽  
pp. 1635-1649
Author(s):  
Kristen MacKenzie-Shalders ◽  
Jaimon T. Kelly ◽  
Daniel So ◽  
Vernon G. Coffey ◽  
Nuala M. Byrne
Keyword(s):  
Systematic Review ◽  
Metabolic Rate ◽  
Meta Analysis ◽  
Resting Metabolic Rate ◽  
Exercise Interventions

Is dietary nitrate/nitrite exposure a risk factor for development of thyroid abnormality? A systematic review and meta-analysis

Nitric Oxide ◽  
2015 ◽  
Vol 47 ◽  
pp. 65-76 ◽  
Author(s):  
Zahra Bahadoran ◽  
Parvin Mirmiran ◽  
Asghar Ghasemi ◽  
Ali Kabir ◽  
Fereidoun Azizi ◽  
...  
Keyword(s):  
Systematic Review ◽  
Risk Factor ◽  
Meta Analysis ◽  
Dietary Nitrate

Effect of inorganic nitrate supplementation on blood pressure in older adults: A systematic review and meta-analysis

Nitric Oxide ◽  
2021 ◽  
Vol 113-114 ◽  
pp. 13-22
Author(s):  
Yayu He ◽  
Jinshu Liu ◽  
Hongwei Cai ◽  
Jun Zhang ◽  
Jiang Yi ◽  
...  
Keyword(s):  
Systematic Review ◽  
Blood Pressure ◽  
Older Adults ◽  
Meta Analysis ◽  
Inorganic Nitrate ◽  
Nitrate Supplementation
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