scholarly journals Fibre Intake Is Associated with Cardiovascular Health in European Children

Nutrients ◽  
2020 ◽  
Vol 13 (1) ◽  
pp. 12
Author(s):  
Susana Larrosa ◽  
Veronica Luque ◽  
Veit Grote ◽  
Ricardo Closa-Monasterolo ◽  
Natalia Ferré ◽  
...  

Background: We aimed at analysing the association between dietary fibre intake during childhood and cardiovascular health markers. Methods: We used observational longitudinal analysis and recorded diet using 3-day diaries at the ages of 3, 4, 5, 6, and 8 years in children from the EU Childhood Obesity Project Trial. At the age of 8, waist circumference, systolic and diastolic blood pressure (SBP and DBP) and biochemical analyses (lipoproteins, triglycerides and homeostasis model for insulin resistance (HOMA-IR)) were evaluated. Those parameters were combined into a cardiometabolic risk score through the sum of their internal z-scores. Results: Four-hundred children (51.8% girls) attended to the 8-year visit with a 3-day diary. Adjusted linear regression models showed that children who repeatedly stayed in the lowest tertile of fibre intake during childhood had higher HOMA-IR (p = 0.004), higher cardiometabolic risk score (p = 0.02) and a nonsignificant trend toward a higher SBP at 8 years. The higher the dietary intake of soluble fibre (from fruits and vegetables) at 8 years, the lower the HOMA-IR and the cardiometabolic risk score (p = 0.002; p = 0.004). SBP was directly associated with fibre from potatoes and inversely with fibre from nuts and pulses. Conclusion: A diet rich in dietary fibre from fruits, vegetables, pulses and nuts from early childhood was associated to a healthier cardiovascular profile, regardless of children’s weight.

Nutrients ◽  
2020 ◽  
Vol 12 (10) ◽  
pp. 3043
Author(s):  
Nour Makarem ◽  
Dorothy D. Sears ◽  
Marie-Pierre St-Onge ◽  
Faris M. Zuraikat ◽  
Linda C. Gallo ◽  
...  

Nightly fasting duration (NFD) and eating timing and frequency may influence cardiometabolic health via their impact on circadian rhythms, which are entrained by food intake, but observational studies are limited. This 1-year prospective study of 116 US women (33 ± 12y, 45% Hispanic) investigated associations of habitual NFD and eating timing and frequency with cardiovascular health (CVH; American Heart Association Life’s Simple 7 score) and cardiometabolic risk factors. NFD, eating timing and frequency, and nighttime eating levels were evaluated from 1-week electronic food records completed at baseline and 1 y. In multivariable-adjusted linear regression models, longer NFD was associated with poorer CVH (β = −0.22, p = 0.016 and β = −0.22, p = 0.050) and higher diastolic blood pressure (DBP) (β = 1.08, p < 0.01 and β = 1.74, p < 0.01) in cross-sectional and prospective analyses, respectively. Later timing of the first eating occasion at baseline was associated with poorer CVH (β = −0.20, p = 0.013) and higher DBP (β = 1.18, p < 0.01) and fasting glucose (β = 1.43, p = 0.045) at 1 y. After adjustment for baseline outcomes, longer NFD and later eating times were also associated with higher waist circumference (β = 0.35, p = 0.021 and β = 0.27, p < 0.01, respectively). Eating frequency was inversely related to DBP in cross-sectional (β = −1.94, p = 0.033) and prospective analyses (β = −3.37, p < 0.01). In cross-sectional analyses of baseline data and prospective analyses, a higher percentage of daily calories consumed at the largest evening meal was associated with higher DBP (β = 1.69, p = 0.046 and β = 2.32, p = 0.029, respectively). Findings suggest that frequent and earlier eating may lower cardiometabolic risk, while longer NFD may have adverse effects. Results warrant confirmation in larger multi-ethnic cohort studies with longer follow-up periods.


2006 ◽  
Vol 96 (S2) ◽  
pp. S45-S51 ◽  
Author(s):  
Jordi Salas-Salvadó ◽  
Mónica Bulló ◽  
Ana Pérez-Heras ◽  
Emilio Ros

Dietary fibre has a range of metabolic health benefits. Through a variety of mechanisms, dietary fibre, and the viscous variety in particular, slows down gastric emptying and intestinal transit, decreases the rate of intestinal carbohydrate absorption, and increases faecal bile acid excretion. Therefore, consumption of some types of soluble fibre can enhance satiety, which is associated with a lower BMI, and reduce blood cholesterol and the postprandial glucose response. Surprisingly, the consumption of insoluble fibre from whole grains, though metabolically inert, has been associated with a reduction in the risk of developing coronary heart disease and diabetes in epidemiological studies. The likely reason is that whole grains, like nuts, legumes and other edible seeds, contain many bioactive phytochemicals and various antioxidants. After cereals, nuts are the vegetable foods that are richest in fibre, which may partly explain their benefit on the lipid profile and cardiovascular health.


2015 ◽  
Vol 114 (9) ◽  
pp. 1480-1486 ◽  
Author(s):  
Ghadeer S. Aljuraiban ◽  
Linda M. O. Griep ◽  
Queenie Chan ◽  
Martha L. Daviglus ◽  
Jeremiah Stamler ◽  
...  

AbstractProspective cohort studies have shown inverse associations between fibre intake and CVD, possibly mediated by blood pressure (BP). However, little is known about the impact of types of fibre on BP. We examined cross-sectional associations with BP of total, insoluble and soluble fibre intakes. Data were used from the INTERnational study on MAcro/micronutrients and blood Pressure (INTERMAP) study, including 2195 men and women aged between 40 and 59 years from the USA. During four visits, eight BP, four 24 h dietary recalls and two 24 h urine samples were collected. Linear regression models adjusted for lifestyle and dietary confounders to estimate BP differences per 2 sd higher intakes of total and individual types of fibre were calculated. After multivariable adjustment, total fibre intake higher by 6·8 g/4184 kJ (6·8 g/1000 kcal) was associated with a 1·69 mmHg lower systolic blood pressure (SBP; 95 % CI −2·97, −0·41) and attenuated to −1·01 mmHg (95 % CI −2·35, 0·34) after adjustment for urinary K. Insoluble fibre intake higher by 4·6 g/4184 kJ (4·6 g/1000 kcal) was associated with a 1·81 mmHg lower SBP (95 % CI −3·65, 0·04), additionally adjusted for soluble fibre and urinary K excretion, whereas soluble fibre was not associated with BP. Raw fruit was the main source of total and insoluble fibre, followed by whole grains and vegetables. In conclusion, higher intakes of fibre, especially insoluble, may contribute to lower BP, independent of nutrients associated with higher intakes of fibre-rich foods.


Nutrients ◽  
2021 ◽  
Vol 13 (11) ◽  
pp. 3826
Author(s):  
Barbara Koroušić Seljak ◽  
Eva Valenčič ◽  
Hristo Hristov ◽  
Maša Hribar ◽  
Živa Lavriša ◽  
...  

Dietary fibre has proven to promote healthy body mass and reduce the risk of non-communicable diseases. To date, in Slovenia, there were only a few outdated studies of dietary fibre intake; therefore, we explored the dietary fibre intake using food consumption data collected in the SI.Menu project. Following the EU Menu methodology, data were collected on representative samples of adolescents, adults, and elderlies using a general questionnaire, a food propensity questionnaire, and two 24 h recalls. The results indicate that the intake of dietary fibre in Slovenia is lower than recommended. The proportion of the population with inadequate fibre intakes (<30 g/day) was 90.6% in adolescents, 89.6% in adults, and 89.3% in elderlies, while mean daily fibre intakes were 19.5, 20.9, and 22.4 g, respectively. Significant determinants for inadequate dietary fibre intake were sex in adolescents and adults, and body mass index in adults. The main food groups contributing to dietary fibre intake were bread and other grain products, vegetables and fruits, with significant differences between population groups. Contribution of fruits and vegetables to mean daily dietary fibre intake was highest in elderlies (11.6 g), followed by adults (10.6 g) and adolescents (8.5 g). Public health strategies, such as food reformulation, promoting whole-meal alternatives, consuming whole foods of plant origin, and careful planning of school meals could beneficially contribute to the overall dietary fibre intake in the population.


Circulation ◽  
2020 ◽  
Vol 141 (Suppl_1) ◽  
Author(s):  
Andrew O Odegaard ◽  
Mercedes R Carnethon ◽  
Sarah M Camhi ◽  
Lisa Chow ◽  
Myron D Gross ◽  
...  

Introduction: The WHO defines overweight and obesity as abnormal or excessive fat accumulation that may impair health. However, for population and clinical classification of overweight and obesity BMI is most commonly used as a proxy for adiposity. Despite the strength of the association between higher BMI and cardiometabolic disease risk across populations, and minimal direct comparison of BMI v. BF%, BMI draws significant criticism as a metric to classify obesity and screen for cardiometabolic risk. Hypothesis: BF% defined obesity classification categories have higher underlying cardiometabolic risk compared to equivalent BMI categories. Methods: We analyzed data from CARDIA study participants from the year 20 exam with concurrent measures of BMI, and BF% measured by Dual-energy X-ray absorptiometry (DXA), plus clinical measures. Sex specific BF% obesity classification categories were defined by evidence-based diagnostic and classification performance measures vs. standard BMI cut points. Underlying cardiometabolic risk was defined by a continuous metabolic syndrome risk score (MetS), consisting of the averaged standardized deviates of the 5 ATP III components. Higher MetS z-scores indicate higher overall risk. MetS z-scores between categories (e.g. obesity defined by BMI v. BF%) were compared by z-tests. Results: The figure reports the distribution of obesity classification categories by the different metrics and underlying cardiometabolic risk. The MetS risk score was significantly higher in BMI defined overweight and obesity compared to BF% defined categories; and BF% defined obesity categories classify a greater prevalence of the population as obese compared to BMI. Results for MetS risk did not differ by race/sex or when including prevalent cardiometabolic disease. Conclusions: Physiologically defined BF% obesity categories classify a greater prevalence of obesity in CARDIA at year 20, whereas there was higher underlying cardiometabolic risk in BMI defined obesity classification categories.


2016 ◽  
Vol 4 (2) ◽  
pp. 90-95 ◽  
Author(s):  
Varsha Jangid ◽  
Meena Godhia ◽  
Neha Sanwalka ◽  
Akash Shukla

To study the association of water and fibre intake with defecatory habits of patients suffering from chronic functional constipation. A cross sectional study was conducted in 100 (51 females) adults suffering from chronic functional constipation. Using the questionnaire, information regarding defecatory habits of patients were collected. The Bristol stool scale was used to identify the type of stools the patient was passing. Dietary fibre intake was assessed by 24-h recall on three random days. Dietary fibre intake (insoluble, soluble and total) was calculated. Total fluid intake throughout the day was also assessed. To study the association of water and fibre intake with defecatory habits of patients suffering from chronic functional constipation. A cross sectional study was conducted in 100 (51 females) adults suffering from chronic functional constipation. Using the questionnaire, information regarding defecatory habits of patients were collected. The Bristol stool scale was used to identify the type of stools the patient was passing. Dietary fibre intake was assessed by 24-h recall on three random days. Dietary fibre intake (insoluble, soluble and total) was calculated. Total fluid intake throughout the day was also assessed. The mean age of the patients was 43.9±14.1 years. Of the 100 patients, 80% of the patients suffered blockage while passing stools, 90% stressed to pass stools. 25% complained of blood in stools and 30^had satisfactory evacuation. Insoluble fibre intake was 28.2±11.7g, soluble fibre intake was 11.9±5.9g and total fibre intake was 40.1±16.3g. Mean water intake of the group was 1358±1090 ml. A significant association of water intake was found with frequency of defecation (χ2 = 16.68), type of stool (χ2=32.51), blood in stools (χ2=11,78) and blockage (χ2=9.69) (p=<0.05). No significant association was seen with stressing (χ2=1.50), satisfactory evacuation (χ2=5.16), urge to defecate (χ2=0.25) and control defecation (χ2=4.61) with water intake (p>0.05). No significant association was found of any defecatory habit and insoluble, soluble or total fibre intake (p>0.05). Water intake is associated with various factors of functional constipation. Awareness to increase water intake to relieve functional constipation needs to be generated.The mean age of the patients was 43.9±14.1 years. Of the 100 patients, 80% of the patients suffered blockage while passing stools, 90% stressed to pass stools. 25% complained of blood in stools and 30^had satisfactory evacuation. Insoluble fibre intake was 28.2±11.7g, soluble fibre intake was 11.9±5.9g and total fibre intake was 40.1±16.3g. Mean water intake of the group was 1358±1090 ml. A significant association of water intake was found with frequency of defecation (χ2 = 16.68), type of stool (χ2=32.51), blood in stools (χ2=11,78) and blockage (χ2=9.69) (p=<0.05). No significant association was seen with stressing (χ2=1.50), satisfactory evacuation (χ2=5.16), urge to defecate (χ2=0.25) and control defecation (χ2=4.61) with water intake (p>0.05). No significant association was found of any defecatory habit and insoluble, soluble or total fibre intake (p>0.05). Water intake is associated with various factors of functional constipation. Awareness to increase water intake to relieve functional constipation needs to be generated.


Circulation ◽  
2020 ◽  
Vol 141 (Suppl_1) ◽  
Author(s):  
Faris M Zuraikat ◽  
Nour Makarem ◽  
Marie-Pierre St-Onge ◽  
MING LIAO ◽  
Hedda L Boege ◽  
...  

Background: An individual’s chronotype, the innate preference for the timing of behaviors such as eating and sleeping, has been linked to various health outcomes. Indeed, we recently demonstrated that evening chronotype was related to poorer cardiovascular health (CVH) in US women. However, the associations of chronotype with specific health behaviors are not well characterized in this population. This is particularly true for diet, the CVH metric for which recommendations are least likely to be met. Therefore, the current study examined the association of chronotype with diet and the role of diet in the chronotype-CVH relation in a diverse sample of women. Hypotheses: Evening chronotype will be associated with higher energy intake and poorer diet quality, including higher dietary energy density (ED), the total kcal per weight of food consumed and an index of the types and amounts of food eaten; these diet factors will mediate an association of chronotype with CVH. Methods: Baseline data from 506 participants enrolled in the AHA Go Red for Women SFRN were examined. Women were 20-76 y of age (mean±SD: 37±16 y); 49% had overweight/obesity and 61% were racial/ethnic minority. Women were categorized as either morning/intermediate or evening chronotype based on their Morningness/Eveningness Questionnaire scores. Dietary ED and daily intakes of food [by weight (g) and energy (kcal)], nutrients (g/1000 kcal), and fruits and vegetables [FV (servings/1000 kcal)] were assessed using the validated Block Brief Food Frequency Questionnaire. Linear regression models were used to examine associations of chronotype with diet. Causal mediation analyses tested whether dietary ED or energy intake mediated a relation between chronotype and CVH (AHA Life’s Simple 7 score). Models were adjusted for age, BMI, race/ethnicity, education, and health insurance. Results: On average, women consumed 1433±862 kcal with a dietary ED of 1.44±0.40 kcal/g. Evening (n=64) vs. morning/intermediate (n=442) chronotype was associated with higher dietary ED (β=0.21, P=0.0001), energy intake (β=448, P=0.0001), and weight of food consumed (β=129.3, P=0.06). Evening chronotype was also related to greater consumption of animal protein (β=1.1, P=0.04) and lower intakes of plant protein (β=-0.66, P=0.006), fiber (β=-2.2, P=0.0005), and FV (β=-1.3, P<0.0001). Dietary ED was a significant partial mediator of the association between chronotype and CVH (percent mediated: 28%, P=0.01). Results were similar when chronotype was analyzed on the continuous scale. Conclusions: In a diverse sample of women, evening chronotype was associated with a less heart-healthy diet, including greater energy intake and poorer diet quality. Moreover, that dietary ED partially mediated the relation between evening chronotype and poor CVH suggests that behavioral interventions to reduce dietary ED may improve CVH in women with evening chronotype.


2021 ◽  
Vol 11 (4) ◽  
pp. 319
Author(s):  
Joanne E. Sordillo ◽  
Sharon M. Lutz ◽  
Michael J. McGeachie ◽  
Jessica Lasky-Su ◽  
Scott T. Weiss ◽  
...  

Genome-wide association studies (GWAS) of response to asthma medications have primarily focused on Caucasian populations, with findings that may not be generalizable to minority populations. We derived a polygenic risk score (PRS) for response to albuterol as measured by bronchodilator response (BDR), and examined the PRS in a cohort of Hispanic school-aged children with asthma. We leveraged a published GWAS of BDR to identify relevant genetic variants, and ranked the top variants according to their Combined Annotation Dependent Depletion (CADD) scores. Variants with CADD scores greater than 10 were used to compute the PRS. Once we derived the PRS, we determined the association of the PRS with BDR in a cohort of Hispanic children with asthma (the Genetics of Asthma in Costa Rica Study (GACRS)) in adjusted linear regression models. Mean BDR in GACRS participants was5.6% with a standard deviation of 10.2%. We observed a 0.63% decrease in BDR in response to albuterol for a standard deviation increase in the PRS (p = 0.05). We also observed decreased odds of a BDR response at or above the 12% threshold for a one standard deviation increase in the PRS (OR = 0.80 (95% CI 0.67 to 0.95)). Our findings show that combining variants from a pharmacogenetic GWAS into a PRS may be useful for predicting medication response in asthma.


2015 ◽  
Vol 13 (2) ◽  
pp. 202-208 ◽  
Author(s):  
Hellen Abreu da Silva ◽  
Júlia Cristina Cardoso Carraro ◽  
Josefina Bressan ◽  
Helen Hermana Miranda Hermsdorff

Objective To identify possible relations between serum uric acid levels and metabolic syndrome and its components in a population with cardiometabolic risk. Methods This cross-sectional study included 80 subjects (46 women), with mean age of 48±16 years, seen at the Cardiovascular Health Program. Results The prevalence of hyperuricemia and metabolic syndrome was 6.3% and 47.1%, respectively. Uric acid level was significantly higher in individuals with metabolic syndrome (5.1±1.6mg/dL), as compared to those with no syndrome or with pre-syndrome (3.9±1.2 and 4.1±1.3mg/dL, respectively; p<0.05). The uric acid levels were significantly higher in men presenting abdominal obesity, and among women with abdominal obesity, lower HDL-c levels and higher blood pressure (p<0.05). Conclusion Uric acid concentrations were positively related to the occurrence of metabolic syndrome and its components, and there were differences between genders. Our results indicate serum uric acid as a potential biomarker for patients with cardiometabolic risk.


2021 ◽  
Vol 26 (Supplement_1) ◽  
pp. e39-e39
Author(s):  
Jean-Baptiste Roberge ◽  
Soren Harnois-Leblanc ◽  
Vanessa McNealis ◽  
Andraea van Hulst ◽  
Tracie A Barnett ◽  
...  

Abstract Primary Subject area Public Health and Preventive Medicine Background The WHO provides body mass index (BMI) curves for infants 0 to &lt; 2 years old, but how these compare to the recommended method (weight-for-length [WFL]) in predicting later adiposity and cardiometabolic measures is uncertain. Objectives Our project aimed to: 1) confirm that WFL and BMI in infancy are associated with adiposity and cardiometabolic measures at 8-10 years old; and 2) compare the predictive ability of the two methods. We hypothesized that both methods would perform similarly. Design/Methods WFL and BMI Z-scores (zWFL and zBMI) at 6, 12, and 18 months of age were computed using data extracted from health booklets, used among participants in a prospective cohort study investigating the natural history of obesity and cardiovascular risk in youth (n = 464). Outcome measures at 8-10 years included adiposity, lipid profile, blood pressure, and insulin dynamics. The relationships between zWFL, zBMI, and each outcome were estimated using multivariable linear regression models. Outcome prediction at 8-10 years was compared between the two methods, using eta-squared and Lin’s concordance correlation. Results zWFL and zBMI were associated with all measures of adiposity at 8-10 years. Associations with other cardiometabolic measures were less consistent. For both zWFL and zBMI across infancy, eta-squared were highly similar and the Lin’s coefficients were markedly high (&gt; 0.991) for all outcomes. Conclusion zBMI measured in infants appeared to be equivalent to zWFL for predicting adiposity and cardiometabolic measures in childhood. This lends support to the sole use of zBMI for growth monitoring and screening of overweight and obesity from birth to 18 years.


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