scholarly journals Efficacy of an Oral Rehydration Solution Enriched with Lactobacillus reuteri DSM 17938 and Zinc in the Management of Acute Diarrhoea in Infants: A Randomized, Double-Blind, Placebo-Controlled Trial

Nutrients ◽  
2018 ◽  
Vol 10 (9) ◽  
pp. 1189 ◽  
Author(s):  
Maria Maragkoudaki ◽  
George Chouliaras ◽  
Antonia Moutafi ◽  
Athanasios Thomas ◽  
Archodoula Orfanakou ◽  
...  
Keyword(s):  
Adverse Effects ◽  
Lactobacillus Reuteri ◽  
Oral Rehydration Solution ◽  
Statistical Significance ◽  
Acute Diarrhoea ◽  
Controlled Study ◽  
Double Blind ◽  
Oral Rehydration ◽  
Number Of Patients ◽  
Rehydration Solution

The efficacy of oral rehydration solution (ORS) enriched with Lactobacillus reuteri DSM 17938 and zinc in infants with acute gastroenteritis, is poorly defined. The aim of this double-blind, randomized, placebo-controlled study, was to assess the efficacy of an ORS enriched with Lactobacillus reuteri DSM 17938 and zinc (ORS+Lr&Z) in well-nourished, non-hospitalized infants with acute diarrhoea. Fifty one infants with acute diarrhoea were randomly assigned to receive either ORS+Lr&Z (28 infants, mean ± SD age 1.7 ± 0.7 years, 21 males), or standard ORS (ORS−Lr&Z; 23 infants, mean ± SD age 1.8 ± 0.7 years, 16 males). Stools volume and consistency were recorded pre- and posttreatment using the Amsterdam Infant Stool Scale and were compared between the two groups, as well as lost work/day care days, drug administration and need for hospitalization. Both groups showed reduction in the severity of diarrhoea on day two (p < 0.001) while, all outcomes showed a trend to be better in the ORS+Lr&Z group, without reaching statistical significance, probably due to the relatively small number of patients. No adverse effects were recorded. In conclusion, both ORS were effective in managing acute diarrhoea in well-nourished, non-hospitalized infants. ORS enriched with L. reuteri DSM 17938 and zinc was well tolerated with no adverse effects.

Glucose vs Sucrose in Oral Rehydration Solutions for Infants and Young Children with Rotavirus-Associated Diarrhea

PEDIATRICS ◽  
1981 ◽  
Vol 67 (1) ◽  
pp. 79-83
Author(s):  
Robert E. Black ◽  
Michael H. Merson ◽  
Philip R. Taylor ◽  
Robert H. Yolken ◽  
Md. Yunus ◽  
...  
Keyword(s):  
Oral Fluid ◽  
Oral Rehydration Solution ◽  
Electrolyte Solutions ◽  
Double Blind ◽  
Oral Rehydration ◽  
Rehydration Solutions ◽  
Cause Of Failure ◽  
Rehydration Solution ◽  
Infants And Young Children ◽  
Weight For Age

The use of oral rehydration solutions containing essential electrolytes and either glucose or sucrose of equal osmolality was compared in a double-blind sequential trial of 784 children with rotavirus-associated diarrhea treated at a center in rural Bangladesh. The oral fluid failure rate was 11.5% for the sucrose-containing solution group and 7.3% for the glucose-containing group (P = NS). Vomiting was a significantly more common cause of failure for the group treated with sucrose-containing oral rehydration solution and was associated with an increased rate of intake of the sweeter sucrose-containing solution. The purging rate was not different for the two groups. The oral fluid failure rates for children in the most underweight category (&lt;60% of expected weight for age) were not different from those for other groups, although, as assessed by purging rate and initial dehydration, the stool losses of members of this group constituted a greater proportion of their body weight. Glucose is the preferred carbohydrate for oral electrolyte solutions, although sucrose can be substituted with only minimum loss of efficacy.

scholarly journals Hydrolysed wheat based oral rehydration solution for acute diarrhoea.

1987 ◽  
Vol 62 (5) ◽  
pp. 440-444 ◽  
Author(s):  
A N Alam ◽  
S A Sarker ◽  
A M Molla ◽  
M M Rahaman ◽  
W B Greenough
Keyword(s):  
Oral Rehydration Solution ◽  
Acute Diarrhoea ◽  
Oral Rehydration ◽  
Rehydration Solution

Effect of a synbiotic on infantile acute gastroenteritis

2013 ◽  
Vol 4 (3) ◽  
pp. 231-235 ◽  
Author(s):  
Z. Gundogdu
Keyword(s):  
Acute Gastroenteritis ◽  
Oral Rehydration Solution ◽  
Acute Diarrhoea ◽  
Control Group ◽  
Common Disease ◽  
Bifidobacterium Lactis ◽  
Oral Rehydration ◽  
Rehydration Solution ◽  
Active Bacteria ◽  
Chicory Inulin

Acute gastroenteritis is still a common disease worldwide. Synbiotics are being used to alleviate the effects of acute gastroenteritis-related diarrhoea. The objective of this study was to determine the efficacy of a synbiotic in reducing the duration of diarrhoea in children with acute gastroenteritis. The study has been carried out on data gathered from children with acute gastroenteritis between the age of three months and 14 years seen in paediatric polyclinics between August 2009 and April 2010. While synbiotic group patients got a sachet containing Bifidobacterium lactis 2211 with a minimum of 5×106 cfu active bacteria and 900 mg chicory inulin twice daily for five days together with an oral rehydration solution, the control group only received an oral rehydration solution. Therapy with synbiotic plus an oral rehydration solution shortened the duration of acute diarrhoea in children by approximately one day compared to oral rehydration solution only.

scholarly journals The Spectrum of Gastroenteritis at the Pediatric Outpatient Clinic,. Department of Child Health, School of Medicine, University of North Sumatera in 1982

2019 ◽  
Vol 28 (1-2) ◽  
pp. 1-13
Author(s):  
Taheng Sebayang ◽  
Atan Baas Sinuhaji ◽  
Tyahaya Bangun ◽  
Manihar D. Marbun ◽  
A. H. Sutanto
Keyword(s):  
Outpatient Clinic ◽  
Oral Rehydration Solution ◽  
Age Group ◽  
Female Ratio ◽  
Oral Rehydration ◽  
Number Of Children ◽  
School Of Medicine ◽  
Number Of Patients ◽  
Rehydration Solution ◽  
Male To Female

The number of children attending the Pediatric Outpatient Clinic of Pirngadi Hospital, Medan, during 1982 was 15.375. Out of these, 1246 (8.1%) had gastroenteritis. Most of the patients (1046 or 83.94%) were under two years old. The male to female ratio was 1.6: I. The peak incidence for allendance was in January, April, and May. Of 1057 patients under  five years old, 383 (36.2%) also had malnutrition. The highest percentage (70. 75%) of those who had malnutrition was found in the I to 2 years age group. Of 370 patients whose Hb level was examined, 185 (50%) had anemia. The highest percentage (67.02%) was in the below 1 year group. Only 360 (28.8%) of gastroenteritis cases received oral rehydration solution. There were 23 (1.85%) cases in which diarrhea lasted longer than 7 days. The number of patients admitted to the ward was 213 (17.07%), and the highest percentage was in the above 3 years age group. The largest number of hospitalized patients was in January (43), February (21), and April (28); while the highest percentage was in April (20.40%), June (21.42%) and August (31.42%). Peak rainfall in Medan during 1982 was in October, November, and December, i.e. much 322.2 mmm,  366.4 and 382 mm, respectively.

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