Effect of a synbiotic on infantile acute gastroenteritis

2013 ◽  
Vol 4 (3) ◽  
pp. 231-235 ◽  
Author(s):  
Z. Gundogdu
Keyword(s):  
Acute Gastroenteritis ◽  
Oral Rehydration Solution ◽  
Acute Diarrhoea ◽  
Control Group ◽  
Common Disease ◽  
Bifidobacterium Lactis ◽  
Oral Rehydration ◽  
Rehydration Solution ◽  
Active Bacteria ◽  
Chicory Inulin

Acute gastroenteritis is still a common disease worldwide. Synbiotics are being used to alleviate the effects of acute gastroenteritis-related diarrhoea. The objective of this study was to determine the efficacy of a synbiotic in reducing the duration of diarrhoea in children with acute gastroenteritis. The study has been carried out on data gathered from children with acute gastroenteritis between the age of three months and 14 years seen in paediatric polyclinics between August 2009 and April 2010. While synbiotic group patients got a sachet containing Bifidobacterium lactis 2211 with a minimum of 5×106 cfu active bacteria and 900 mg chicory inulin twice daily for five days together with an oral rehydration solution, the control group only received an oral rehydration solution. Therapy with synbiotic plus an oral rehydration solution shortened the duration of acute diarrhoea in children by approximately one day compared to oral rehydration solution only.

scholarly journals Efficacy of an Oral Rehydration Solution Enriched with Lactobacillus reuteri DSM 17938 and Zinc in the Management of Acute Diarrhoea in Infants: A Randomized, Double-Blind, Placebo-Controlled Trial

Nutrients ◽  
2018 ◽  
Vol 10 (9) ◽  
pp. 1189 ◽  
Author(s):  
Maria Maragkoudaki ◽  
George Chouliaras ◽  
Antonia Moutafi ◽  
Athanasios Thomas ◽  
Archodoula Orfanakou ◽  
...  
Keyword(s):  
Adverse Effects ◽  
Lactobacillus Reuteri ◽  
Oral Rehydration Solution ◽  
Statistical Significance ◽  
Acute Diarrhoea ◽  
Controlled Study ◽  
Double Blind ◽  
Oral Rehydration ◽  
Number Of Patients ◽  
Rehydration Solution

The efficacy of oral rehydration solution (ORS) enriched with Lactobacillus reuteri DSM 17938 and zinc in infants with acute gastroenteritis, is poorly defined. The aim of this double-blind, randomized, placebo-controlled study, was to assess the efficacy of an ORS enriched with Lactobacillus reuteri DSM 17938 and zinc (ORS+Lr&Z) in well-nourished, non-hospitalized infants with acute diarrhoea. Fifty one infants with acute diarrhoea were randomly assigned to receive either ORS+Lr&Z (28 infants, mean ± SD age 1.7 ± 0.7 years, 21 males), or standard ORS (ORS−Lr&Z; 23 infants, mean ± SD age 1.8 ± 0.7 years, 16 males). Stools volume and consistency were recorded pre- and posttreatment using the Amsterdam Infant Stool Scale and were compared between the two groups, as well as lost work/day care days, drug administration and need for hospitalization. Both groups showed reduction in the severity of diarrhoea on day two (p < 0.001) while, all outcomes showed a trend to be better in the ORS+Lr&Z group, without reaching statistical significance, probably due to the relatively small number of patients. No adverse effects were recorded. In conclusion, both ORS were effective in managing acute diarrhoea in well-nourished, non-hospitalized infants. ORS enriched with L. reuteri DSM 17938 and zinc was well tolerated with no adverse effects.

scholarly journals Hydrolysed wheat based oral rehydration solution for acute diarrhoea.

1987 ◽  
Vol 62 (5) ◽  
pp. 440-444 ◽  
Author(s):  
A N Alam ◽  
S A Sarker ◽  
A M Molla ◽  
M M Rahaman ◽  
W B Greenough
Keyword(s):  
Oral Rehydration Solution ◽  
Acute Diarrhoea ◽  
Oral Rehydration ◽  
Rehydration Solution

Role of a Soy-Based Lactose-Free Formula in the Outpatient Management of Diarrhea

PEDIATRICS ◽  
1991 ◽  
Vol 87 (5) ◽  
pp. 619-622
Author(s):  
Mathuram Santosham ◽  
Julius Goepp ◽  
Barbara Burns ◽  
Raymond Reid ◽  
R. Bradley Sack ◽  
...  
Keyword(s):  
Acute Diarrhea ◽  
Oral Rehydration Solution ◽  
Caloric Intake ◽  
The United States ◽  
Control Group ◽  
Early Feeding ◽  
Oral Rehydration ◽  
Feeding Group ◽  
Rehydration Solution

The introduction of a soy-based, lactose-free formula during the acute phase of diarrheal illness in infants has been shown to reduce stool output and duration of diarrhea in hospitalized patients. In the United States, most infants with acute diarrhea are treated as outpatients. In the present study, infants with diarrhea who were treated as outpatients were randomly assigned to receive either a soy-based, lactose-free formula alternating with oral rehydration solution from the beginning of therapy ("early feeding") or oral rehydration solution alone for the first 24 hours of therapy, followed by a soy-based, lactose-free formula alternating with oral rehydration solution (control group). Twenty-nine infants were randomly assigned to the early-feeding group and 27 to the control group. Twenty-one (72%) of 29 in the early-feeding group resolved their diarrhea at the end of 48 hours of therapy compared with 12 (44%) of 27 in the group fed oral rehydration solution only (P = .02). It is concluded that the introduction of a soy-based, lactose-free formula from the beginning of therapy for acute diarrhea in children treated as outpatients is safe and may shorten duration of diarrhea while maintaining adequate caloric intake.

Acceptability and efficacy of a gel hypotonic oral rehydration solution in children with acute gastroenteritis

2015 ◽  
Vol 27 (5) ◽  
pp. 523-526 ◽  
Author(s):  
Annalisa Passariello ◽  
Rita Nocerino ◽  
Gianluca Terrin ◽  
Gaetano Cecere ◽  
Giulio De Marco ◽  
...  
Keyword(s):  
Acute Gastroenteritis ◽  
Oral Rehydration Solution ◽  
Oral Rehydration ◽  
Rehydration Solution
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