scholarly journals Bergenia Genus: Traditional Uses, Phytochemistry and Pharmacology

Molecules ◽  
2020 ◽  
Vol 25 (23) ◽  
pp. 5555
Author(s):  
Bhupendra Koul ◽  
Arvind Kumar ◽  
Dhananjay Yadav ◽  
Jun-O. Jin
Keyword(s):  
Traditional Medicine ◽  
Central Asia ◽  
Detailed Analysis ◽  
Bioactive Compounds ◽  
Biological Activities ◽  
Chemical Constituents ◽  
Drug Formulation ◽  
Traditional Uses ◽  
Pharmacological Significance ◽  
Phytochemical Studies

Bergenia (Saxifragaceae) genus is native to central Asia and encompasses 32 known species. Among these, nine are of pharmacological relevance. In the Indian system of traditional medicine (Ayurveda), “Pashanabheda” (stone breaker) is an elite drug formulation obtained from the rhizomes of B. ligulata. Bergenia species also possess several other biological activities like diuretic, antidiabetic, antitussive, insecticidal, anti-inflammatory, antipyretic, anti-bradykinin, antiviral, antibacterial, antimalarial, hepatoprotective, antiulcer, anticancer, antioxidant, antiobesity, and adaptogenic. This review provides explicit information on the traditional uses, phytochemistry, and pharmacological significance of the genus Bergenia. The extant literature concerned was systematically collected from various databases, weblinks, blogs, books, and theses to select 174 references for detailed analysis. To date, 152 chemical constituents have been identified and characterized from the genus Bergenia that belong to the chemical classes of polyphenols, phenolic-glycosides, lactones, quinones, sterols, tannins, terpenes, and others. B. crassifolia alone possesses 104 bioactive compounds. Meticulous pharmacological and phytochemical studies on Bergenia species and its conservation could yield more reliable compounds and products of pharmacological significance for better healthcare.

scholarly journals Ficus caricaL. (Moraceae): Phytochemistry, Traditional Uses and Biological Activities

2013 ◽  
Vol 2013 ◽  
pp. 1-8 ◽  
Author(s):  
Shukranul Mawa ◽  
Khairana Husain ◽  
Ibrahim Jantan
Keyword(s):  
Organic Acids ◽  
Traditional Medicine ◽  
Volatile Compounds ◽  
Bioactive Compounds ◽  
Biological Activities ◽  
Chemical Constituents ◽  
Antimicrobial Activities ◽  
Therapeutic Agents ◽  
Therapeutic Effects ◽  
Phytochemical Studies

This paper describes the botanical features ofFicus caricaL. (Moraceae), its wide variety of chemical constituents, its use in traditional medicine as remedies for many health problems, and its biological activities. The plant has been used traditionally to treat various ailments such as gastric problems, inflammation, and cancer. Phytochemical studies on the leaves and fruits of the plant have shown that they are rich in phenolics, organic acids, and volatile compounds. However, there is little information on the phytochemicals present in the stem and root. Reports on the biological activities of the plant are mainly on its crude extracts which have been proven to possess many biological activities. Some of the most interesting therapeutic effects include anticancer, hepatoprotective, hypoglycemic, hypolipidemic, and antimicrobial activities. Thus, studies related to identification of the bioactive compounds and correlating them to their biological activities are very useful for further research to explore the potential ofF. caricaas a source of therapeutic agents.

Traditional Uses, Chemical Constituents and Biological Activities of Plants from the Genus Thymus

2019 ◽  
Vol 16 (9) ◽  
Author(s):  
Xiao Li ◽  
Ting He ◽  
Xiuhuan Wang ◽  
Meng Shen ◽  
Xin Yan ◽  
...  
Keyword(s):  
Biological Activities ◽  
Chemical Constituents ◽  
Traditional Uses

scholarly journals Traditional Uses, Phytochemistry, and Pharmacology of Elegia Species: A Review

2021 ◽  
Vol 90 (1) ◽  
pp. 4
Author(s):  
Panagiotis Lymperis ◽  
Ekaterina-Michaela Tomou ◽  
Marco Nuno De Canha ◽  
Namrita Lall ◽  
Helen Skaltsa
Keyword(s):  
Biological Activities ◽  
Chemical Constituents ◽  
Pharmacological Activities ◽  
Traditional Uses ◽  
Comprehensive Search ◽  
Extensive Information ◽  
The Subject ◽  
Phytochemical Profile ◽  
Ecological Dominance ◽  
New Research

In South Africa, plants belonging to the Restionaceae family possess an ecological dominance. As a result, they have been the subject of numerous morphological, anatomical, and evolutionary studies. However, few studies have focused on their phytochemical profile and their potential pharmacological activities. The genus Elegia L. is the second largest of this family comprising 52 species, which are mainly used as materials for thatching. Limited studies on the chemical constituents of Elegia species and their importance as medicinal plants have been undertaken. This review provides constructive and extensive information about the botanical characterization, distribution, traditional uses, phytochemistry and pharmacology of the genus Elegia. A comprehensive search of previously published literature was performed for studies on this genus, using databases with different key search words. This survey documented 52 Elegia species summarizing their previous taxonomic classification. In addition, 14 species were found to be studied for their phytochemical profile, revealing 14 chemical compounds. Concerning their biological activities, only one species (E. tectorum (L.f.) Moline and H.P.Linder) is reported for its anti-wrinkle activity. Moreover, two species are locally used for thatching and as materials for brooms. The present review highlights the Elegia genus as an important source of bioactive phytochemicals with flavonol glycosides being the main metabolites and reveals the uncharted territory of this genus for new research studies.

scholarly journals Radix Bupleuri: A Review of Traditional Uses, Botany, Phytochemistry, Pharmacology, and Toxicology

2017 ◽  
Vol 2017 ◽  
pp. 1-22 ◽  
Author(s):  
Fude Yang ◽  
Xiaoxv Dong ◽  
Xingbin Yin ◽  
Wenping Wang ◽  
Longtai You ◽  
...  
Keyword(s):  
Biological Activities ◽  
Biological Properties ◽  
Pharmacokinetic Studies ◽  
Triterpenoid Saponins ◽  
Traditional Uses ◽  
Pure Compounds ◽  
Radix Bupleuri ◽  
High Doses ◽  
Phytochemical Studies

Radix Bupleuri (Chaihu) has been used as a traditional medicine for more than 2000 years in China, Japan, Korea, and other Asian countries. Phytochemical studies demonstrated that this plant contains essential oils, triterpenoid saponins, polyacetylenes, flavonoids, lignans, fatty acids, and sterols. Crude extracts and pure compounds isolated from Radix Bupleuri exhibited various biological activities, such as anti-inflammatory, anticancer, antipyretic, antimicrobial, antiviral, hepatoprotective, neuroprotective, and immunomodulatory effects. However, Radix Bupleuri could also lead to hepatotoxicity, particularly in high doses and with long-term use. Pharmacokinetic studies have demonstrated that the major bioactive compounds (saikosaponins a, b2, c, and d) were absorbed rapidly in rats after oral administration of the extract of Radix Bupleuri. This review aims to comprehensively summarize the traditional uses, botany, phytochemistry, pharmacology, toxicology, and pharmacokinetics of Radix Bupleuri reported to date with an emphasis on its biological properties and mechanisms of action.

scholarly journals Recent Advances in Kaempferia Phytochemistry and Biological Activity: A Comprehensive Review

Nutrients ◽  
2019 ◽  
Vol 11 (10) ◽  
pp. 2396 ◽  
Author(s):  
Elshamy ◽  
Mohamed ◽  
Essa ◽  
Abd-ElGawad ◽  
Alqahtani ◽  
...  
Keyword(s):  
Skin Diseases ◽  
Biological Activities ◽  
Chemical Constituents ◽  
Principal Component ◽  
Comprehensive Review ◽  
Traditional Uses ◽  
Biological Studies ◽  
Tract Infections

Background: Plants belonging to the genus Kaempferia (family: Zingiberaceae) are distributed in Asia, especially in the southeast region, and Thailand. They have been widely used in traditional medicines to cure metabolic disorders, inflammation, urinary tract infections, fevers, coughs, hypertension, erectile dysfunction, abdominal and gastrointestinal ailments, asthma, wounds, rheumatism, epilepsy, and skin diseases. Objective: Herein, we reported a comprehensive review, including the traditional applications, biological and pharmacological advances, and phytochemical constituents of Kaempheria species from 1972 up to early 2019. Materials and methods: All the information and reported studies concerning Kaempheria plants were summarized from library and digital databases (e.g., Google Scholar, Sci-finder, PubMed, Springer, Elsevier, MDPI, Web of Science, etc.). The correlation between the Kaempheria species was evaluated via principal component analysis (PCA) and agglomerative hierarchical clustering (AHC), based on the main chemical classes of compounds. Results: Approximately 141 chemical constituents have been isolated and reported from Kaempferia species, such as isopimarane, abietane, labdane and clerodane diterpenoids, flavonoids, phenolic acids, phenyl-heptanoids, curcuminoids, tetrahydropyrano-phenolic, and steroids. A probable biosynthesis pathway for the isopimaradiene skeleton is illustrated. In addition, 15 main documented components of volatile oils of Kaempheria were summarized. Biological activities including anticancer, anti-inflammatory, antimicrobial, anticholinesterase, antioxidant, anti-obesity-induced dermatopathy, wound healing, neuroprotective, anti-allergenic, and anti-nociceptive were demonstrated. Conclusions: Up to date, significant advances in phytochemical and pharmacological studies of different Kaempheria species have been witnessed. So, the traditional uses of these plants have been clarified via modern in vitro and in vivo biological studies. In addition, these traditional uses and reported biological results could be correlated via the chemical characterization of these plants. All these data will support the biologists in the elucidation of the biological mechanisms of these plants.

scholarly journals Traditional Uses, Chemical Profile and Biological Activities of Piper hispidum Sw.: a Review

2021 ◽  
Vol 11 (5) ◽  
pp. 13115-13129
Keyword(s):  
Web Of Science ◽  
Biological Activities ◽  
Raw Material ◽  
Medical Professionals ◽  
Benzoic Acids ◽  
Chemical Profile ◽  
High Demand ◽  
Scientific Databases ◽  
Traditional Uses ◽  
Phytochemical Studies

Piper hispidum Sw. (Piperaceae) (syn. Piper hispidinervum) is a medicinal shrub distributed in Central and South America, widely used as an astringent, diuretic, stimulant for unblocking the liver and stopping hemorrhages. The plant has great interest among researchers due to the production of essential oil and important raw material for the chemical industry, which has a high demand for cosmetic, insecticide, and pesticide industries. In this review, traditional uses, phytochemicals, and biological activities of P. hispidum are comprehensively and systematically summarized through searching scientific databases, including Science Direct, PubMed, Google Scholar, Scopus, and Web of Science. Phytochemical studies revealed the presence of amides, benzoic acids, flavonoids, phenylpropanoids, butenolides, phenol, and essential oils; hence it has several activities, such as antioxidant, antibacterial, α-amylase, insecticidal, schistosomicidal, leishmanial, larvicidal, antiplasmodial, cytotoxicity, estrogenic and serotonergic properties. This review is expected to draw the attention of medical professionals and the general public towards P. hispidum as well as to open the door for detailed research in the future.

scholarly journals A perspective review of phytochemistry and pharmacology of the Syzygium genus

2021 ◽  
Vol 12 (2) ◽  
pp. 1490-1495
Author(s):  
Yuniarni U ◽  
Sukandar E Y ◽  
Fidrianny I
Keyword(s):  
Traditional Medicine ◽  
Pharmacological Activity ◽  
Therapeutic Potential ◽  
Biological Activities ◽  
Ornamental Plants ◽  
Chemical Compounds ◽  
Chemical Components ◽  
Pharmacological Activities ◽  
Widespread Species ◽  
Traditional Uses

Syzygium is a genus of the Myrtaceae family consisting of large and widespread species from Africa, Asia, Australia, and throughout Oceania and the Pacific region. Some have been cultivated for bearing fruit, ornamental plants and used as traditional medicine. This article excavated Syzygium genus which was focused on traditional uses, chemical compounds and biological activities related to treatment of syndrome metabolic. All information was obtained from the scientific literature such as Science Direct, Google Scholar, Scopus and PubMed. Several species were known to have therapeutic potential and used in traditional Chinese medicine, Ayurveda, and herbal medicine in Indonesia. Traditionally, Syzygium is known for its therapeutic purposes such as coughing, diarrhea, colds, dysentery, inflammation, pain, skin, and mouth infections. Only a few species have been scientifically studied to verify their usage as traditional medicine. There were many reports on the traditional uses and medicinal effects of Syzygium plants, but only a few review articles mainly about phytochemical constituents and their role in pharmacological activities. The present reviews highlight the phytochemical and pharmacological activity of various species of the Syzygium genus. The pharmacological activities were discussed in this article focused to metabolic syndrome treatment, such as antidiabetic, antihyperlipidemic, antioxidant and antihypertensive activities. Chemical components isolated mainly flavonoid, terpenoids/sesquiterpenoid, sterols, and lignan. Several bioactive compounds have been identified correlated with pharmacological activity, but the chemical compounds were different for each species.

scholarly journals A Review of the Phytochemistry, Traditional Uses, and Biological Activities of the Genus Ballota and Otostegia

Planta Medica ◽  
2019 ◽  
Vol 85 (11/12) ◽  
pp. 869-910
Author(s):  
Sergio Rosselli ◽  
Gianfranco Fontana ◽  
Maurizio Bruno
Keyword(s):  
Middle East ◽  
Traditional Medicine ◽  
North Africa ◽  
Biological Activities ◽  
Mediterranean Area ◽  
Biological Properties ◽  
Traditional Uses ◽  
Chemical Profiles ◽  
Ancient Times ◽  
The Mediterranean

AbstractThe 2 genera Ballota and Otostegia, belonging to the Lamiaceae family, are closely related taxonomically and found mainly in the Mediterranean area, Middle East, and North Africa. Since ancient times, they have been largely employed in traditional medicine for their biological properties such as antimicrobial, anti-inflammatory, antispasmodic, insecticidal, anti-malaria, etc. Phytochemical investigations of Ballota and Otostegia species have revealed that diterpenoids are the main constituents of the genera. A large number of flavonoids and other metabolites were also identified. This review, covering literature from 1911 up to 2018, includes traditional uses, chemical profiles (both of volatile and nonvolatile metabolites), and biological properties of all the taxa of these 2 genera studied to date.

The Chemical Constituents and Bioactivities of Psoralea corylifolia Linn.: A Review

2016 ◽  
Vol 44 (01) ◽  
pp. 35-60 ◽  
Author(s):  
Xuenong Zhang ◽  
Wenwen Zhao ◽  
Ying Wang ◽  
Jinjian Lu ◽  
Xiuping Chen
Keyword(s):  
Medicinal Plant ◽  
Skin Diseases ◽  
Biological Activities ◽  
Chemical Constituents ◽  
Psoralea Corylifolia ◽  
Active Components ◽  
Anti Oxidant ◽  
Main Components ◽  
Phytochemical Studies ◽  
Important Medicinal Plant

Psoralea corylifolia Linn. (P. corylifolia) is an important medicinal plant with thousands of years of clinical application. It has been widely used in many traditional Chinese medicine formulas for the treatment of various diseases such as leucoderma and other skin diseases, cardiovascular diseases, nephritis, osteoporosis, and cancer. Phytochemical studies indicated that coumarins, flavonoids, and meroterpenes are the main components of P. corylifolia, and most of these components are present in the seeds or fruits. The extracts and active components of P. corylifolia demonstrated multiple biological activities, including estrogenic, antitumor, anti-oxidant, antimicrobial, antidepressant, anti-inflammatory, osteoblastic, and hepatoprotective activities. This paper systematically summarized literatures on the chemical constituents and biological activities of P. corylifolia, which provided useful information for the further research and development toward this potent medicinal plant.

scholarly journals Chemical constituents and biological activities of Artocarpus heterophyllus lam (Jackfruit): A review

2021 ◽  
Vol 4 (1) ◽  
pp. 005-009
Author(s):  
Bhad Pranay Raja ◽  
Bobde Meeneri Vilas ◽  
G Sibi
Keyword(s):  
Bioactive Compounds ◽  
Mode Of Action ◽  
Biological Activities ◽  
Chemical Constituents ◽  
Deciduous Tree ◽  
Anticancer Activities ◽  
Artocarpus Heterophyllus ◽  
Edible Fruit ◽  
Pharmacological Studies ◽  
Promising Source

Artocarpus (Moraceae) is a deciduous tree with appreciable importance as a source of edible fruit and is widely used in folk medicines. The extracts and metabolites of Artocarpus heterophyllus particularly those from leaves, bark, stem and fruit possess several useful bioactive compounds. This review indents to compile various studies on A. heterophyllus and critically evaluates its ethnomedical and ethnopharmacological properties. Several pharmacological studies from A. heterophyllus have conclusively established their mode of action in anti-inflammatory, antimicrobial, antioxidant and anticancer activities. Based on the available data, it is concluded that Artocarpus as a promising source of useful products and opens up new avenues for novel therapeutics.

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