scholarly journals Ficus caricaL. (Moraceae): Phytochemistry, Traditional Uses and Biological Activities

2013 ◽  
Vol 2013 ◽  
pp. 1-8 ◽  
Author(s):  
Shukranul Mawa ◽  
Khairana Husain ◽  
Ibrahim Jantan
Keyword(s):  
Organic Acids ◽  
Traditional Medicine ◽  
Volatile Compounds ◽  
Bioactive Compounds ◽  
Biological Activities ◽  
Chemical Constituents ◽  
Antimicrobial Activities ◽  
Therapeutic Agents ◽  
Therapeutic Effects ◽  
Phytochemical Studies

This paper describes the botanical features ofFicus caricaL. (Moraceae), its wide variety of chemical constituents, its use in traditional medicine as remedies for many health problems, and its biological activities. The plant has been used traditionally to treat various ailments such as gastric problems, inflammation, and cancer. Phytochemical studies on the leaves and fruits of the plant have shown that they are rich in phenolics, organic acids, and volatile compounds. However, there is little information on the phytochemicals present in the stem and root. Reports on the biological activities of the plant are mainly on its crude extracts which have been proven to possess many biological activities. Some of the most interesting therapeutic effects include anticancer, hepatoprotective, hypoglycemic, hypolipidemic, and antimicrobial activities. Thus, studies related to identification of the bioactive compounds and correlating them to their biological activities are very useful for further research to explore the potential ofF. caricaas a source of therapeutic agents.

scholarly journals Bergenia Genus: Traditional Uses, Phytochemistry and Pharmacology

Molecules ◽  
2020 ◽  
Vol 25 (23) ◽  
pp. 5555
Author(s):  
Bhupendra Koul ◽  
Arvind Kumar ◽  
Dhananjay Yadav ◽  
Jun-O. Jin
Keyword(s):  
Traditional Medicine ◽  
Central Asia ◽  
Detailed Analysis ◽  
Bioactive Compounds ◽  
Biological Activities ◽  
Chemical Constituents ◽  
Drug Formulation ◽  
Traditional Uses ◽  
Pharmacological Significance ◽  
Phytochemical Studies

Bergenia (Saxifragaceae) genus is native to central Asia and encompasses 32 known species. Among these, nine are of pharmacological relevance. In the Indian system of traditional medicine (Ayurveda), “Pashanabheda” (stone breaker) is an elite drug formulation obtained from the rhizomes of B. ligulata. Bergenia species also possess several other biological activities like diuretic, antidiabetic, antitussive, insecticidal, anti-inflammatory, antipyretic, anti-bradykinin, antiviral, antibacterial, antimalarial, hepatoprotective, antiulcer, anticancer, antioxidant, antiobesity, and adaptogenic. This review provides explicit information on the traditional uses, phytochemistry, and pharmacological significance of the genus Bergenia. The extant literature concerned was systematically collected from various databases, weblinks, blogs, books, and theses to select 174 references for detailed analysis. To date, 152 chemical constituents have been identified and characterized from the genus Bergenia that belong to the chemical classes of polyphenols, phenolic-glycosides, lactones, quinones, sterols, tannins, terpenes, and others. B. crassifolia alone possesses 104 bioactive compounds. Meticulous pharmacological and phytochemical studies on Bergenia species and its conservation could yield more reliable compounds and products of pharmacological significance for better healthcare.

Chemical Constituents and Biological Activities of Cordia Myxa L.: A Review

2021 ◽  
Vol 11 ◽  
Author(s):  
Varinder Singh ◽  
Ankita Sood ◽  
Simran Pruthi ◽  
Manjinder Singh ◽  
Balraj Saini ◽  
...  
Keyword(s):  
Biological Activities ◽  
Chemical Constituents ◽  
Antimicrobial Activities ◽  
Functional Health ◽  
Future Research ◽  
Health Food ◽  
Toxicological Evaluation ◽  
Cordia Myxa ◽  
Chronic Fever ◽  
Tract Infections

Background: Cordia myxa L. (CM) is a valuable ethnomedicinal plant from Boraginaceae family. Traditionally, CM parts especially fruits and leaves are used in chest and urinary tract infections, diarrhoea, dysentery, tuberculosis, liver and spleen disorders, chronic fever, malaria etc. Objective: Despite of known importance and uses, CM has gained relatively less attention of researchers and concise reviews revealing the medicinal potential of CM are scanty. The present review summarizes the chemical constituents and biological activities of CM and aims to stimulate future research to develop it as a functional health food. Results: Analysis of literature on CM showed that its fruits are a rich source of nutrients and are frequently employed in wide ailments such as urinary and respiratory tract infections, chronic fever, liver disorders, asthma, used as anthelmintic, diuretic, expectorant and purgative. Scientific studies have shown the antidiabetic, analgesic, anti-inflammatory, anti-cancer, antioxidant, antiplasmodial, hepatoprotective, hypotensive, antiulcer and antimicrobial activities of CM. More than 45 compounds belonging to carbohydrates, steroids, carotenoids, phenols, flavonoids and alkaloids have been reported from various parts of CM. Conclusion: Systematic preclinical studies support the traditional claims of CM. The analysis of available literature showed that CM could be developed as a drug. Further, studies such as detailed pharmacological and toxicological evaluation, isolation of bioactive compounds, quantitative phytochemistry and structure activity relationship are scanty and thus, crucial to be addressed for uplifting the scientific value of this revered medicinal plant.

scholarly journals Pharmacology and Phytochemistry of Ecuadorian Medicinal Plants: An Update and Perspectives

2021 ◽  
Vol 14 (11) ◽  
pp. 1145
Author(s):  
Chabaco Armijos ◽  
Jorge Ramírez ◽  
Melissa Salinas ◽  
Giovanni Vidari ◽  
Alírica I. Suárez
Keyword(s):  
Chemical Composition ◽  
Medicinal Plants ◽  
Secondary Metabolites ◽  
Essential Oils ◽  
Volatile Compounds ◽  
Biological Activities ◽  
Indigenous Communities ◽  
Therapeutic Agents ◽  
Practical Applications ◽  
Pharmacological Studies

The use of plants as therapeutic agents is part of the traditional medicine that is practiced by many indigenous communities in Ecuador. The aim of this study was to update a review published in 2016 by including the studies that were carried out in the period 2016–July 2021 on about 120 Ecuadorian medicinal plants. Relevant data on raw extracts and isolated secondary metabolites were retrieved from different databases, resulting in 104 references. They included phytochemical and pharmacological studies on several non-volatile compounds, as well as the chemical composition of essential oils (EOs). The tested biological activities are also reported. The potential of Ecuadorian plants as sources of products for practical applications in different fields, as well the perspectives of future investigations, are discussed in the last part of the review.

scholarly journals Fireweed (Epilobium angustifolium L.): botany, phytochemistry and traditional uses. A review

2019 ◽  
Vol 65 (3) ◽  
pp. 51-63 ◽  
Author(s):  
Artur Adamczak ◽  
Mariola Dreger ◽  
Katarzyna Seidler-Łożykowska ◽  
Karolina Wielgus
Keyword(s):  
Antimicrobial Activities ◽  
Raw Material ◽  
Therapeutic Effects ◽  
Traditional Uses ◽  
Epilobium Angustifolium ◽  
Oenothein B ◽  
Phytochemical Studies ◽  
First Time ◽  
Vegetation Phase ◽  
Time Of Harvest

Summary Fireweed (Epilobium angustifolium L., Onagraceae) is one of important medicinal plants used especially in the treatment of urogenital disorders, including benign prostatic hyperplasia (BPH) and prostatitis. The therapeutic effects of E. angustifolium extracts comprise antiproliferative, anti-inflammatory, immunomodulatory, antioxidant, and also antimicrobial activities. The aim of the present review was to provide the information on the botany, phytochemistry and traditional uses of E. angustifolium. This plant is a widespread circumboreal species of North America and Eurasia, tolerant in terms of habitat conditions, and often occupying man-made open habitats. Phytochemical studies on E. angustifolium resulted in the identification of about 250 different metabolites, including about 170 substances found for the first time in this plant in the last six years (2014–2019). Fireweed has an abundance of polyphenolic compounds, particularly ellagitannins. Oenothein B and quercetin-3-O-glucuronide are proposed as markers for the identification and standardization of the plant raw material. E. angustifolium exhibits significant phytochemical variability in relation to the geographical origin, plant part and time of harvest/vegetation phase. Survey of the ethnobotanical literature showed that the above-mentioned species has been widely used not only as a medicinal, but also as an edible, honey and decorative plant.

scholarly journals A REVIEW ON MARINE ALGAE AND ITS APPLICATIONS

2020 ◽  
pp. 21-27
Author(s):  
CHANDRA VELUCHAMY ◽  
RADHA PALANISWAMY
Keyword(s):  
Bioactive Compounds ◽  
Marine Algae ◽  
Biological Activities ◽  
Therapeutic Agents ◽  
The Novel ◽  
Marine Microbes ◽  
Pharmacological Activities ◽  
Nutritional Values ◽  
Other Substances ◽  
Living Organisms

The ocean is the major essential source of structurally unique natural products that are mainly present in living organisms. The essential products extracted from marine microbes and marine algae are highly analyzed areas in instinctive product research. Marine algae are the novel food with potential nutritional values used for multiple purposes in industry and medicine. They show pharmacological activities which are helpful for the invention of bioactive compounds. Furthermore, marine algae have shown to provide an abundant source of natural bioactive compounds with antidiabetic, anti-inflammatory, antiviral, antifungal, hypolipidemic, antioxidant, anti-hypercholesterolemia, antibacterial, and antineoplastic properties. They produce new secondary metabolites that possess biological activities and have the potential to be developed as therapeutic agents. Macroalgal lectins, fucoidans, kainoids, and other substances have been routinely used in the research of biomedical and also have biological activities. The potential pharmaceutical, medicinal, and research applications of these compounds are discussed.

scholarly journals MUSCARI ARMENIACUM LEICHTLIN (GRAPE HYACINTH): PHYTOCHEMISTRY AND BIOLOGICAL ACTIVITIES REVIEW

2019 ◽  
Vol 12 (1) ◽  
pp. 68
Author(s):  
Dmitry Olegovich Bokov
Keyword(s):  
Biological Activity ◽  
Biological Activities ◽  
Biologically Active Substances ◽  
Biologically Active ◽  
Antimutagenic Activity ◽  
Therapeutic Effects ◽  
Herbal Drug ◽  
Ribosome Inactivating Proteins ◽  
Phytochemical Studies ◽  
Active Substances

This review focuses on the Muscari armeniacum Leichtlin (Asparagaceae Juss) biologically active substances composition presented in the Aireal and underground parts and finding their possible therapeutic effects. The systematic review is dedicated to the composition of biologically active substances, including recent advances in the biological activity investigation, phytochemical studies, and biotechnology methods of plant material producing. Various electronic search engines such as Google, Google Scholar, scientific literature, publishing sites, and electronic databases such as PubMed, Wiley, Springer, and Science Direct had been searched and data obtained. Other online academic libraries such as E-library and specific ethnopharmacological literature had been searched systematically for more exhaustive information on the crude herbal drug. The chemical composition of M. armeniacum biologically active substances is established; it contains anthocyanins (delphinidin and cyanidin derivatives), homoisoflavonoids, polyhydroxylated pyrrolizidine alkaloids (hyacinthacines A1, A2, A3, and B3), oligoglycosides (Muscarosides), and ribosome-inactivating proteins (musarmins). Recent physicochemical analytical procedures for components determination and hyacinthacines synthesis pathways are mentioned. Moreover, future prospects and trends in the research of this plant have been proposed. We have reviewed researches conducted on M. armeniacum especially in areas of its use in medicine, phytochemicals, biological activity, and developed analytical methods. M. armeniacum possesses antioxidant, antimutagenic activity, and specific glycosidase inhibitory activity; M. armeniacum can be used for the production of potential anticancer, antiviral, antidiabetic, and anti-obesity drugs. It should be noted that more pharmacognostic, pharmacological studies are needed for giving further information on the clinical practice and standardization procedures for the crude herbal drug.

scholarly journals Phytochemicals and Biological Activities of Garcinia morella (Gaertn.) Desr.: A Review

Molecules ◽  
2020 ◽  
Vol 25 (23) ◽  
pp. 5690
Author(s):  
Hosakatte Niranjana Murthy ◽  
Dayanand Dalawai ◽  
Yaser Hassan Dewir ◽  
Abdullah Ibrahim
Keyword(s):  
Organic Acids ◽  
Bioactive Compounds ◽  
Phenolic Acids ◽  
Biological Activities ◽  
Active Constituents ◽  
Evergreen Tree ◽  
Wide Range ◽  
Anti Inflammatory ◽  
Larvicidal Activities ◽  
Seed Extracts

Garcinia morella (Gaertn.) Desr. is an evergreen tree that yields edible fruits, oil, and resin. It is a source of “gamboge”, a gum/resin that has a wide range of uses. The fruits, leaves, and seeds of this tree are rich in bioactive compounds, including xanthones, flavonoids, phenolic acids, organic acids, and terpenoids. Evidence from different studies has demonstrated the antioxidant, antifungal, antiviral, hepatoprotective, anticancer, anti-inflammatory, antibacterial, and larvicidal activities of the fruit, leaf, and seed extracts of G. morella. This review summarizes the information on the phytochemicals of G. morella and the biological activities of its active constituents.

scholarly journals Chemical constituents of leaves Dialium cochinchinense Pierre

2021 ◽  
Vol 4 (3) ◽  
pp. 1131-1136
Author(s):  
Vu Thi Huyen ◽  
Doan Thi Thuy Ai ◽  
Nguyen Thi Hien
Keyword(s):  
Secondary Metabolites ◽  
Nmr Spectra ◽  
Spectroscopic Analysis ◽  
Biological Activities ◽  
Chemical Constituents ◽  
Antimicrobial Activities ◽  
Tropical Regions ◽  
First Report ◽  
Isolation And Characterization

The genus Dialium belongs to the Caesalpinioideae family, consisting of approximately 30 species distributed in the tropical regions. Secondary metabolites from the  Dialium genus have been reported to exhibit various biological activities including antioxidant, cytotoxicity and antimicrobial activities. This work describes the isolation and characterization of five compounds from the leaves of Dialium cochinchinense Pierre. Their structures were established by spectroscopic analysis, including MS and NMR spectra. Accordingly, the isolated compounds were identified to be lupeone (1), b-sitostenone (2), β-sitosterol (3), daucosterol (4), and dihydrokaempferide (5). To the best of our knowledge, this is the first report of the isolation of compounds 1 and 5 from the genus Dialium.

scholarly journals Antimicrobial activities of citronella (Cymbopogon nardus) essential oil against several oral pathogens and its volatile compounds

2020 ◽  
Vol 32 (1) ◽  
pp. 1
Author(s):  
Henny Zaliyana Ahmad Kamal ◽  
Tuan Nadrah Naim Tuan Ismail ◽  
Erry Mochamad Arief ◽  
Kannan Thirumulu Ponnuraj
Keyword(s):  
Essential Oil ◽  
Volatile Compounds ◽  
Inhibitory Activity ◽  
Antimicrobial Activities ◽  
Raw Material ◽  
Gas Chromatography Mass Spectrometry ◽  
Therapeutic Effects ◽  
Cymbopogon Nardus ◽  
Oral Pathogens

Introduction: Cymbopogon nardus is a strong aromatic plant with relevant medicinal properties due to its essential chemical compounds and its potential therapeutic effects. This study was aimed to evaluate the antimicrobial activities of citronella essential oil against several oral pathogens and to identify the volatile compounds. Methods: The essential oil of C. nardus was purchased from Excellent Wisdom Sdn. Bhd., Malaysia. The source of raw material was collected from Malacca, the southern region of Malaysia, and the company made its taxonomic identification. An experimental in-vitro study was conducted on the essential oil processed from C. nardus genus Cymbopogon of Poaceae family. The in-vitro antimicrobial activities of C. nardus essential oil were evaluated against Streptococcus mutans (ATCC 25175), Streptococcus sobrinus (ATCC 33478), and Candida albicans (ATCC 10231) using agar well diffusion assay. The identification of the volatile compounds was performed using gas chromatography-mass spectrometry (GC-MS). Results: The C. nardus essential oil exhibited inhibitory activity against C. albicans at the concentration of 6.25%, whereby the inhibitory activity against S. mutans and S. sobrinus began at the concentration of 25%. The antimicrobial activity of C. nardus essential oil was statistically significant at the concentration of 50% in all tested pathogens. The GC-MS analysis of the C. nardus essential oil revealed the presence of few constituents, which include monoterpenes, diterpenes, sesquiterpenes and phenolic compounds. Monoterpenes were the major identified terpenoids and contributed to 54.45% of the total volatile composition. The main identified monoterpenes were citronellal (11.35%), z-Citral (11.34%), β-Myrcene (6.70%), and β-Trans-ocimene (6.03%), which was the first time β-Myrcene and β-Trans-ocimene was found in high percentage. Conclusion: C. nardus essential oil is an active antibacterial agent against several oral pathogens, and the percentages of active volatile compounds are different within different origins.

scholarly journals Evaluation of Chemical Constituents of Crude Oil

2020 ◽  
pp. 79-83
Author(s):  
Chinedu Imo ◽  
Ejim Moses Ijagem
Keyword(s):  
Crude Oil ◽  
Traditional Medicine ◽  
Volatile Compounds ◽  
Antimicrobial Agents ◽  
Chemical Constituents ◽  
Food Additives ◽  
Toxic Substance ◽  
Raw Material ◽  
Detector Model

The chemical constituents of crude oil were evaluated in this study. Crude oil is used for many purposes. It is commonly used for production of fuel and in traditional medicine for various purposes. Some people also use crude oil as antidote for poisons. Analysis of the chemical constituents of crude oil was carried out with the use of GC (model No. 7890B) and MS detector (model 5977A). Several chemical constituents with various functions were detected in the crude oil. Some of the chemical constituents detected have been reported to be used for the production of some fuels, pesticides, volatile compounds, fragrance, food additives and antimicrobial agents. This study therefore showed that various important chemicals/compounds useful in traditional medicine and for industrial uses are present in crude oil, thereby making it a good raw material for industrial and medicinal purposes. However, some constituents of crude oil are known to be able to cause toxicity, making crude oil a toxic substance.

Sign in / Sign up

Export Citation Format

Share Document