scholarly journals Characterization of Bioactive Components in Edible Algae

Marine Drugs ◽  
2020 ◽  
Vol 18 (1) ◽  
pp. 65 ◽  
Author(s):  
Leonel Pereira
Keyword(s):  
Bioactive Components ◽  
Edible Algae

From the origin of our planet, about 4 [...]

scholarly journals Beyond Alkaloids: Novel Bioactive Natural Products From Lobelia Species

2021 ◽  
Vol 12 ◽  
Author(s):  
Qinfang Zheng ◽  
Ye Wang ◽  
Shuihan Zhang
Keyword(s):  
Molecular Mechanisms ◽  
The Novel ◽  
Bioactive Components ◽  
Research Focus ◽  
Bioactive Natural Products ◽  
Hyperactivity Disorder ◽  
Multicenter Phase ◽  
Major Shift ◽  
Significant Attention

In this work, we reviewed the progress in the phytochemical and biological investigations of bioactive components derived from medicinally valuable Lobelia species. In the last 60 years, Lobelia has garnered significant attention from the phytochemist from around the world, majorly due to the discovery of bioactive piperidine alkaloids (e.g., lobinaline and lobeline) in the early 1950s. Later, lobeline underwent clinical trials for several indications including the treatment of attention deficit hyperactivity disorder and a multicenter phase three trial for smoking cessation. Subsequently, several other alkaloids derived from different species of Lobelia were also investigated for their pharmacological characteristics. However, in the last few years, the research focus has started shifting to the characterization of the other novel chemical classes. The major shift has been noticed due to the structurally similar alkaloid components, which essentially share similar pharmacological, physicochemical, and toxicological profiles. In this review, we present an up-to-date overview of their progress with special attention to understanding the molecular mechanisms of the novel bioactive components.

Antimicrobial and antioxidant characterization of bioactive components from Chlorococcum minutum

2020 ◽  
Vol 35 ◽  
pp. 100567 ◽  
Author(s):  
Mostafa E. Elshobary ◽  
Rania A. El-Shenody ◽  
Mohamed Ashour ◽  
Hossain M. Zabed ◽  
Xianghui Qi
Keyword(s):  
Bioactive Components

scholarly journals Side-stream products of malting: a neglected source of phytochemicals

2020 ◽  
Vol 4 (1) ◽  
Author(s):  
Ville M. Koistinen ◽  
Marjo Tuomainen ◽  
Pekka Lehtinen ◽  
Petri Peltola ◽  
Seppo Auriola ◽  
...  
Keyword(s):  
Chronic Diseases ◽  
Main Product ◽  
Whole Grains ◽  
Major Contributor ◽  
Whole Grain ◽  
Bioactive Components ◽  
Side Stream ◽  
Phytochemical Profile ◽  
Whole Foods

AbstractWhole grain consumption reduces the risk of several chronic diseases. A major contributor to the effect is the synergistic and additive effect of phytochemicals. Malting is an important technological method to process whole grains; the main product, malted grain, is used mainly for brewing, but the process also yields high amounts of side-stream products, such as rootlet. In this study, we comprehensively determined the phytochemical profile of barley, oats, rye, and wheat in different stages of malting and the subsequent extraction phases to assess the potential of malted products and side-streams as a dietary source of bioactive compounds. Utilizing semi-quantitative LC–MS metabolomics, we annotated 285 phytochemicals from the samples, belonging to more than 13 chemical classes. Malting significantly altered the levels of the compounds, many of which were highly increased in the rootlet. Whole grain cereals and the malting products were found to be a diverse and rich source of phytochemicals, highlighting the value of these whole foods as a staple. The characterization of phytochemicals from the 24 different sample types revealed previously unknown existence of some of the compound classes in certain species. The rootlet deserves more attention in human nutrition, rather than its current use mainly as feed, to benefit from its high content of bioactive components.

scholarly journals Characterization of Sheep Milk Extracellular Vesicle-miRNA by Sequencing and Comparison with Cow Milk

Animals ◽  
2020 ◽  
Vol 10 (2) ◽  
pp. 331 ◽  
Author(s):  
Suyu Quan ◽  
Xuemei Nan ◽  
Kun Wang ◽  
Linshu Jiang ◽  
Junhu Yao ◽  
...  
Keyword(s):  
Small Rnas ◽  
Regulatory Element ◽  
Signal Transmission ◽  
Extracellular Vesicle ◽  
Ovis Aries ◽  
Cow Milk ◽  
Bioactive Components ◽  
Sheep Milk ◽  
Bioactive Component

Milk can mediate maternal-neonatal signal transmission by the bioactive component extracellular vesicles (EVs), which select specific types of miRNA to encapsulate. The miRNA profiling of sheep milk EVs was characterized by sequencing and compared with that of cow milk. Nanoparticle tracking analysis revealed that the concentration of sheep milk EVs was 1.3 ± 0.09 × 1012 particles/mL and the diameter was peaked at 131.2 ± 0.84 nm. Sheep milk EVs contained various small RNAs, including tRNA, Cis-regulatory element, rRNA, snRNA, other Rfam RNA, and miRNA, which held about 36% of all the small RNAs. In total, 84 types of miRNA were annotated with Ovis aries by miRBase (version 22.0) in sheep milk EVs, with 75 shared types of miRNAs in all samples. The miR-26a, miR-191, let-7f, let-7b and miR-10b were highly expressed both in cow and sheep milk EVs, and 14 sheep milk EV-miRNAs in the top 20, occupying 98% of the total expression, were immune-related. Although pathway analysis showed different potential functions of cow and sheep milk EV-miRNAs, there were still some shared points: lipid metabolism (phospholipase D, glycerophospholipid and glycosylphosphatidylinositol), calcium metabolism, and nerve conduction (axon guidance and synapse). This study provides reference for the bioactive components in the milk of different species.

Czy warto jeść algi?

2018 ◽  
Vol 21 (1A) ◽  
Author(s):  
Zygmunt Zdrojewicz ◽  
Bartosz Bieżyński ◽  
Piotr Krajewski
Keyword(s):  
Marine Algae ◽  
Biological Diversity ◽  
Biologically Active ◽  
Diverse Group ◽  
Bioactive Components ◽  
Mineral Salts ◽  
Vast Number ◽  
Edible Algae ◽  
Anti Cancer ◽  
Nutrition Value

Algae is a very diverse group of aquatic and land organisms that has been used by humans for ages. Nowadays algae are constantly growing in popularity. Thanks to their richness in nutrients and bioactive components (mineral salts, carbohydrates, protein, EFA, vitamins or microelements), they have found use in dietetics and many branches of medicine. Due to an increase of algae-related studies, many biologically active compounds have been discovered. Described as anti-inflammatory, anti-bacterial, anti-viral, anti-allergic or even anti-cancer, marine algae may be used in the treatment of many diseases. Currently one of their main uses is related to obesity but the action of algae is much more than that. The vast number of edible algae species and their biological diversity significantly increase their potential and the growing amount of research they undergo, give us reasons to assume that marine algae can play a big part in “nutrition of the future”. The aim of this study is to present the nutrition value of marine algae and their significance in medical treatment.

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