scholarly journals Antibiofilm and Protein-Repellent Polymethylmethacrylate Denture Base Acrylic Resin for Treatment of Denture Stomatitis

Materials ◽  
2021 ◽  
Vol 14 (5) ◽  
pp. 1067
Author(s):  
Salwa O. Bajunaid ◽  
Bashayer H. Baras ◽  
Abdulrahman A. Balhaddad ◽  
Michael D. Weir ◽  
Hockin H. K. Xu

Candida albicans (C. albicans) biofilm is a common etiological factor in denture stomatitis. The purpose of this study was to investigate the effects of incorporating 2-methacryloyloxyethyl phosphorylcholine (MPC) as a protein repellent into a new high-impact denture acrylic (HIPA) resin on the surface roughness, solution pH, and C. albicans biofilm adhesion to the denture base. The new acrylic denture resin base was formulated by mixing MPC into HIPA resin at mass fractions of 1.5%, 3%, and 4.5%. Surface roughness was measured using a Mitutoyo surface roughness tester. C. albicans biofilm growth and viability were assessed via colony forming unit counts. The pH of the biofilm growth medium was measured using a digital pH meter. Adding MPC to the HIPA resin at percentages of 1.5% and 3% increased the roughness values significantly (p < 0.05), while adding 4.5% MPC resulted in no difference in roughness values to that of the control group (p > 0.05). All experimental groups demonstrated neutral pH values (pH ≅ 7) and were not significantly different from each other (p > 0.05). Incorporating 2-methacryloyloxyethyl phosphorylcholine at 4.5% resulted in a significant (≅1 log) colony-forming unit reduction compared with the control group with 0% MPC (p < 0.05). A fungal-retarding denture acrylic resin was developed through the incorporation of MPC for its protein-repelling properties. This newly developed denture acrylic material has the potential to prevent oral microbial infections, such as denture stomatitis.

Polymers ◽  
2022 ◽  
Vol 14 (2) ◽  
pp. 230
Author(s):  
Salwa Omar Bajunaid ◽  
Bashayer H. Baras ◽  
Michael D. Weir ◽  
Hockin H. K. Xu

Denture stomatitis is a multifactorial pathological condition of the oral mucosa that affects up to 72% of denture wearers. It is commonly seen on the palatal mucosa and characterized by erythema on the oral mucosa that are in contact with the denture surface. The aim of this study was to incorporate 2-methacryloyloxyethyl phosphorylcholine (MPC) and dimethylaminohexadecyl methacrylate (DMAHDM) into a high impact polymethylmethacrylate heat-cured denture base acrylic resin as a potential treatment for denture stomatitis. We used a comparative study design to examine the effect of incorporating MPC as a protein repellent agent and DMAHDM as an antifungal agent to prevent the adherence of Candida albicans to the denture base material. The dual incorporation of MPC and DMAHDM reduced C. albicans biofilm colony-forming unit by two orders of magnitude when compared to the control group devoid of the bioactive agents. Although the addition of MPC and DMAHDM alone or in combination significantly reduced the flexural strength of the material, they showed reduced roughness values when compared to control groups. This new denture acrylic resin provides the benefit of enhancing C. albicans biofilm elimination through dual mechanisms of action, which could potentially reduce the prevalence of denture stomatitis.


2021 ◽  
Vol 17 (1) ◽  
pp. 22-26
Author(s):  
Kadek Ayu Wirayuni ◽  
◽  
I Made Hendri Dwi Saputra ◽  

Introduction: The denture base is the part of the removable denture that is supported by good adaptation to the underlying oral tissue. Most of the denture bases are made of acrylic or polymethyl methacrylate resin, better known as PMMA. However, the acrylic resin also has disadvantages such as easily broken and absorbs liquids both water and chemicals. The chemical absorption like alcohol, ethanol, and some drinks that contain acidic materials will chemically be induced with acrylic resin and settle in the pores of the acrylic resin. The chemical damage or defect creates roughness on the surface of the acrylic resin which can cause cracking or crazing and a decrease in surface strength and hardness. Materials and Methods: The method used in this research was a laboratory experimental design with a post-test-only control group using 12 samples consisting of 2 different types of samples by measuring the surface roughness of the acrylic resin after immersing the sample with a predetermined time. Results and Discussions: One-way ANOVA test results showed a significant difference in surface roughness after the samples immersion with a value of p = 0.006 (p <0.05). Conclusions: Based on this research, can be concluded that there is an increase in the surface roughness of the heated polymerized acrylic resin for 3 hours and 4 hours of immersion. The longer the heated polymerized acrylic resin is soaked in arak hence the level of surface roughness increases.


Materials ◽  
2021 ◽  
Vol 14 (1) ◽  
pp. 221
Author(s):  
Avi Meirowitz ◽  
Arkadi Rahmanov ◽  
Eti Shlomo ◽  
Helena Zelikman ◽  
Eran Dolev ◽  
...  

Denture stomatitis is a common manifestation of oral candidiasis affecting some 65% of denture wearers. This condition is initiated by the adherence of Candida albicans to denture base acrylic resin. The present study aimed to test the in vitro effect of traditional and novel fabrication methods on Candida albicans adhesion to denture base samples. Denture based acrylic discs were fabricated using: (i) computerized milling, (ii) 3D printing, (iii) heat curing, and (iv) cold curing. Discs were tested for surface roughness (Ra), hydrophobicity (contact angle), mucin adsorption (Bradford assay), and Candida albicans adhesion. 3D printing significantly increased microbial cell adhesion as compared with heat curing, and computerized milling significantly decreased it. These results were associated with mucin adsorption levels rather than surface roughness. Results suggest that 3D printing may increase the risk for developing denture stomatitis, whereas computerized milling may decrease it as compared with traditional heat curing denture base fabrication.


2018 ◽  
Vol 6 (2) ◽  
pp. 339
Author(s):  
Afthin Maritta Noviyanti ◽  
Rahardyan Parnaadji ◽  
FX Ady Soesetijo

The most used denture base materials is heat cured acrylic resin. The disadvantages of acrylic resin are easy to absorb water and porosity that can increase surface roughness. The surface roughness can facilitate the attachment of microorganisms and accumulation of plaque. The cleansing of mechanical denture use electric toothbrush and denture cleanser paste. This paste uses natural materials from robusta coffee beans that decrease surface roughness. To determine the effectivity of robusta coffee beans paste as a denture cleanser to the surface roughness of heat cured acrylic resin.  This study was an experimental laboratory with the research design the post test only  control group design. Total sample of 36 samples in size (65 x 10 x 2,5) mm which consisted of 4 groups: control group without brushing, group A  brushed with electric toothbrush and a placebo paste, group B brushed with electric toothbrush and robusta coffee beans paste 25%, and group C  brushed with electric toothbrush and robusta coffee beans paste 50%. Brushing was done for 22 minutes, then measured the surface roughness of dentures. Robusta coffee bean paste was less effective as a denture cleanser agent against the surface roughness of the heat cured acrylic resin. Robusta coffee beans paste 50% can be used as a denture cleanser. Keyword: acrylic resin, electric toothbrush, robusta coffee bean paste, surface roughness  


2020 ◽  
Vol 5 (1) ◽  
pp. 36-43
Author(s):  
Gladis Aprilla Rizki ◽  
Sri Wahyuningsih Rais ◽  
Martha Mozartha

Alcoholic beverages can be consumed in any group age, and it may be consumed by an individual using denture. Fluid absorption by heat-cured acrylic resin as a material of a denture base was able to cause an increase in its surface roughness. Absorption of an organic solvent such as the ethanol in an alcoholic beverage(s) could even increase the effect. This study aimed to evaluate the effect of alcohol beverages on surface roughness of heat-cured acrylic resin denture base. Samples (n=24) were prepared from heat-cured acrylic resin (25x25x5 mm). They were divided into 4 groups and the pre-test surface roughness was measured. Samples of each group were immersed for 10 minutes into the solution (distilled water as the control group, beer, wine, and whiskey as the test groups). After stored in artificial saliva for 23 hours, the samples were immersed into the solution, completing a period of 24 hours. This procedure was performed for 7 consecutive days and the post-test surface roughness was measured. Data were statistically analyzed using the Kruskal-Walis test. There was a significant difference in surface roughness measurement before and after the immersion (p<0.05). Whiskey was most affecting the surface roughness of heat-cured acrylic resin denture base. Alcoholic beverages could increase the surface roughness of heat cure acrylic resin denture base. Keywords: Alcoholic beverages; Heat-cured acrylic denture base; Surface roughness


Author(s):  
Amal Nawasrah ◽  
Mohammed Gad ◽  
Mai El Zayat

Statement of problem: Henna has been added to polymethylmethacrylate (PMMA) as a new type of antifungal agent; however, its effect on the latter&rsquo;s physical properties has not been investigated. Purpose: This study aimed to evaluate the effect of the addition of various henna concentrations on the surface roughness and hardness of PMMA denture base material. Materials and Methods: A total of 99 specimens of rectangular-shaped (10&times;20&times;3 mm3) acrylic specimens were prepared from heat-cured acrylic resin. Specimens were divided into one control group without the addition of henna and five test groups, which were prepared by adding Yamani henna powder to acrylic powder at concentrations of 1wt%, 2.5wt%, 5wt%, 7.5wt%, and 10wt%. The polymer was added to the monomer before being mixed, packed, and processed using the conventional water bath method. After processing, specimens were finished and polished, then kept in distilled water for 48+2 h. A profilometer and Vickers hardness tester were used to measure surface roughness and hardness respectively. Statistical data analysis was conducted via SPSS version 20.0 (IBM, USA). Results: The addition of henna at varying concentrations significantly increased surface roughness values (P &le; 0.01) while decreasing hardness (P &le; 0.0001). The most favorable addition value was 1% henna between all henna groups. Conclusion: The addition of henna to the acrylic resin may negatively affect the surface properties of PMMA acrylic denture base.


2016 ◽  
Vol 1 (2) ◽  
pp. 99
Author(s):  
Dewi Puspitasari ◽  
Diana Wibowo ◽  
Elda Rosemarwa

Acrylic resin denture base has the properties absorbing that affecting physical and mechanical properties. One of the physical properties of acrylic resin is surface roughness. The aim of the study was to find out the roughness effect on heat cured acrylic that was immersed in alkaline peroxide and 75% celery (Apium graveoens L) extract as a disinfectant solution. The study was a true experimental and posttest with control group designed with a rectangular shape size 65 x 10 x 3.3 mm based on the ISO standard 1567, six samples were used for alkaline peroxide, celery extract 75% and aquadest group for 5 and 15 days. A Surface Roughness Tester was used for the surface roughness changes observation. The statistical test used One-way ANOVA and post hoc Bonferroni. The results of this study showed the value of roughness on 5 days for alkaline peroxide (1.51 µm) is greater than celery extract (0.36µm) and aquadest (0.30 µm). The soaking for 15 days in alkaline peroxide (1.52 µm) is greater than 75% celery extracts (0.38 µm) and aquadest (0.34 µm). Alkaline peroxide caused higher roughness value of heat cured acrylic resin than 75% celery extract.


Symmetry ◽  
2021 ◽  
Vol 13 (6) ◽  
pp. 976
Author(s):  
Saleh Zidan ◽  
Nikolaos Silikas ◽  
Julfikar Haider ◽  
Javad Jahantigh ◽  
Ahmed Alhareb ◽  
...  

Artificial biomaterials are being developed for use in denture base with symmetrical properties to restore the aesthetics and functionalities. The rough surface of denture base resin promotes the adhesion of microorganisms and plaque accumulation. This study aimed to explore the consequences of polishing times on the surface roughness of high-impact (HI) heat-polymerized PMMA denture base acrylic resin reinforced with zirconia nanoparticles (nanocomposite). Thirty specimens (25 ± 0.50 mm in diameter and 2 ± 0.10 mm thickness) were fabricated from HI PMMA by adding zirconia nanoparticles at different concentrations of (0 wt.%, 1.5 wt.%, 3 wt.%, 5 wt.%, 7 wt.%, and 10 wt.%). Specimens were divided into six groups (n = 5) and surface roughness (Ra) was measured before and after polishing with a standard protocol for one and two minutes. The addition of zirconia in PMMA at low concentrations (1.5 wt.%, 3 wt.%, and 5 wt.%) did not negatively affect the surface finish of the denture base composites following conventional polishing and remained below the clinically acceptable limit (0.2 µm). After one minute of polishing, only the 10 wt.% zirconia (0.17 ± 0.03 µm) demonstrated a substantial rise in median surface roughness, in comparison with the control group (0.11 ± 0.01 µm). It is concluded that the group containing 3 wt.% (0.10 ± 0.01 µm) of zirconia is the optimum concentration to obtain the best symmetrical surface finish after two minutes of polishing.


2016 ◽  
Vol 1 (2) ◽  
pp. 237
Author(s):  
Dewi Puspitasari ◽  
Diana Wibowo ◽  
Elda Rosemarwa

<p>Acrylic resin denture base has the properties absorbing that affecting physical and mechanical properties. One of the physical properties of acrylic resin is surface roughness. The aim of the study was to find out the roughness effect on heat cured acrylic that was immersed in alkaline peroxide and 75% celery (<em>Apium graveoens L</em>)<em> </em>extract as a disinfectant solution. The study was a true experimental and posttest with control group designed with a rectangular shape size 65 x 10 x 3.3 mm based on the ISO standard 1567, six samples were used for alkaline peroxide, celery extract 75% and <em>aquades</em><em>t</em> group for 5 and 15 days. A Surface Roughness Tester was used for the surface roughness changes observation. The statistical test used One-way ANOVA and post hoc Bonferroni. The results of this study showed the value of roughness on 5 days for alkaline peroxide (1.51 µm) is greater than celery extract (0.36µm) and <em>aquades</em><em>t</em> (0.30 µm). The soaking for 15 days in alkaline peroxide (1.52 µm) is greater than 75% celery extracts (0.38 µm) and <em>aquadest </em>(0.34 µm). Alkaline peroxide caused higher roughness value of heat cured acrylic resin than 75% celery extract.</p>


2017 ◽  
Vol 29 (1) ◽  
Author(s):  
Pocut Aya Sofya ◽  
Liana Rahmayani ◽  
Rico Riski Candra Purnama

Introduction: The absorption of fluid in the heat cured acrylic resin is able to cause the increase in surface roughness. Absorption of acidic fluid such as soft drinks can cause even higher increase of surface roughness. The objective of this study was to determined the effect of soft drinks towards heat cured acrylic resin denture base surface roughness. Methods: Specimens of this study were 32 pieces of specimen with the size of 12×12×3 mm. Sixteen pieces of specimens were kept in aquadest as a control group and 16 pieces of specimens were immersed in the soft drinks as the treatment group. Initial surface roughness was measured using surface roughness tester. The specimens were then immersed in both immersion media for 2 days. After immersion, the surface roughness of specimens were measured again. Results: Data obtained on the roughness measurements were analyzed using paired t test with the results of the analysis showed a significant difference (p<0.05). Conclusion: It was concluded that there was increased in heat cured acrylic resin denture base surface roughness after immersed in soft drinks solvent.


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