scholarly journals The hetero-Friedel-Crafts-Bradsher Cyclizations with Formation of Ring Carbon-Heteroatom (P, S) Bonds, Leading to Organic Functional Materials

Materials ◽  
2020 ◽  
Vol 13 (21) ◽  
pp. 4751
Author(s):  
Joanna Skalik ◽  
Marek Koprowski ◽  
Ewa Różycka-Sokołowska ◽  
Piotr Bałczewski
Keyword(s):  
Flame Retardants ◽  
Bond Formation ◽  
Functional Materials ◽  
Semiconducting Materials ◽  
Conjugated Molecules ◽  
Comprehensive Review ◽  
Ring Carbon ◽  
New Methods ◽  
Cyclic Molecules ◽  
Methods Of Synthesis

The interest in functional materials possessing improved properties led to development of new methods of their synthesis, which allowed to obtain new molecular arrangements with carbon and heteroatom motifs. Two of the classical reactions of versatile use are the Friedel-Crafts and the Bradsher reactions, which in the new heteroatomic versions allow to replace ring carbon atoms by heteroatoms. In the present work, we review methods of synthesis of C–S and C–P bonds utilizing thia- and phospha-Friedel-Crafts-Bradsher cyclizations. Single examples of C–As and lack of C–Se bond formation, involving two of the closest neighbors of P and S in the periodic table, have also been noted. Applications of the obtained π-conjugated molecules, mainly as semiconducting materials, flame retardants, and resins hardeners, designed on the basis of five- and six-membered cyclic molecules containing ring phosphorus and sulfur atoms, are also included. This comprehensive review covers literature up to August 2020.

scholarly journals Nanoscale Crystalline Sheets and Vesicles Assembled from Nonplanar Cyclic π-Conjugated Molecules

Research ◽  
2019 ◽  
Vol 2019 ◽  
pp. 1-11 ◽  
Author(s):  
Huang Tang ◽  
Zhewei Gu ◽  
Haifeng Ding ◽  
Zhibo Li ◽  
Shiyan Xiao ◽  
...  
Keyword(s):  
Self Assembly ◽  
Carbon Nanomaterials ◽  
Materials Science ◽  
Functional Materials ◽  
Building Blocks ◽  
Molecular Scaffolds ◽  
Conjugated Molecules ◽  
New Class ◽  
Supramolecular Architectures ◽  
Cyclic Molecules

A fundamental challenge in chemistry and materials science is to create new carbon nanomaterials by assembling structurally unique carbon building blocks, such as nonplanar π-conjugated cyclic molecules. However, self-assembly of such cyclic π-molecules to form organized nanostructures has been rarely explored despite intensive studies on their chemical synthesis. Here we synthesized a family of new cycloparaphenylenes and found that these fully hydrophobic and nonplanar cyclic π-molecules could self-assemble into structurally distinct two-dimensional crystalline multilayer nanosheets. Moreover, these crystalline multilayer nanosheets could overcome inherent rigidity to curve into closed crystalline vesicles in solution. These supramolecular assemblies show that the cyclic molecular scaffolds are homogeneously arranged on the surface of nanosheets and vesicles with their molecular isotropic x-y plane standing obliquely on the surface. These supramolecular architectures that combined exact crystalline order, orientation-specific arrangement of π-conjugated cycles, controllable morphology, uniform molecular pore, superior florescence quench ability, and photoluminescence are expected to give rise to a new class of functional materials displaying unique photonic, electronic, and biological functions.

Synthesis of Drugs and Biorelevant N-heterocycles Employing Recent Advances in C-N Bond Formation

2020 ◽  
Vol 24 (20) ◽  
pp. 2293-2340
Author(s):  
Firdoos Ahmad Sofi ◽  
Prasad V. Bharatam
Keyword(s):  
Kinase Inhibitors ◽  
Bond Formation ◽  
Comprehensive Review ◽  
Biologically Relevant ◽  
Lead Compounds ◽  
Heterocyclic Molecules ◽  
The Past ◽  
Anti Cancer ◽  
Modern Methods ◽  
Bond Formation Reactions

C-N bond formation is a particularly important step in the generation of many biologically relevant heterocyclic molecules. Several methods have been reported for this purpose over the past few decades. Well-known named reactions like Ullmann-Goldberg coupling, Buchwald-Hartwig coupling and Chan-Lam coupling are associated with the C-N bond formation reactions. Several reviews covering this topic have already been published. However, no comprehensive review covering the synthesis of drugs/ lead compounds using the C-N bond formation reactions was reported. In this review, we cover many modern methods of the C-N bond formation reactions, with special emphasis on metal-free and green chemistry methods. We also report specific strategies adopted for the synthesis of drugs, which involve the C-N bond formation reactions. Examples include anti-cancer, antidepressant, anti-inflammatory, anti-atherosclerotic, anti-histaminic, antibiotics, antibacterial, anti-rheumatic, antiepileptic and anti-diabetic agents. Many recently developed lead compounds generated using the C-N bond formation reactions are also covered in this review. Examples include MAP kinase inhibitors, TRKs inhibitors, Polo-like Kinase inhibitors and MPS1 inhibitors.

scholarly journals Methods of synthesis, characteristics, and environmental applications of Mxene: A comprehensive review

Chemosphere ◽  
2021 ◽  
pp. 131607
Author(s):  
Jagadeesan Aravind Kumar ◽  
Pandurangan Prakash ◽  
Thangavelu Krithiga ◽  
Duvuru Joshua Amarnath ◽  
Jayapal Prem Kumar ◽  
...  
Keyword(s):  
Environmental Applications ◽  
Comprehensive Review ◽  
Methods Of Synthesis

Recent Progress in Iodine‐Catalysed C−O/C−N Bond Formation of 1,3‐Oxazoles: A Comprehensive Review

2021 ◽  
Vol 6 (4) ◽  
pp. 754-787
Author(s):  
Sanjeev Dhawan ◽  
Vishal Kumar ◽  
Pankaj S. Girase ◽  
Sithabile Mokoena ◽  
Rajshekhar Karpoormath
Keyword(s):  
Recent Progress ◽  
Bond Formation ◽  
Comprehensive Review

A comparative study of the catalytic activity of Co- and CoFe2O4-NPs in C–N and C–O bond formation: synthesis of benzimidazoles and benzoxazoles from o-haloanilides

2016 ◽  
Vol 40 (12) ◽  
pp. 10474-10481 ◽  
Author(s):  
Abdol R. Hajipour ◽  
Zahra Khorsandi
Keyword(s):  
Catalytic Activity ◽  
Comparative Study ◽  
Bond Formation ◽  
New Methods ◽  
Comparison Of The Results

Herein, new methods and a comparison of the results for dehalogenative intramolecular C–X bond formation using two inexpensive and efficient catalysts are reported.

scholarly journals AROMI NATURALI: LEGISLAZIONE E SINTESI

2020 ◽  
Author(s):  
Stefano Serra
Keyword(s):  
Legal Regulations ◽  
New Methods ◽  
Methods Of Synthesis ◽  
Natural Flavors

This report describes the legal regulations concerning flavour production, classification and marketing. The effect that the legislation itself has brought in the development of new methods of synthesis of natural flavors is described in detail.

New Methods of Synthesis, Structure and Aminomethylation of 4-Imino-2-(dicyanomethylene)-3-azaspiro[5.5]undecane-1,5-dicarbonitrile

2021 ◽  
Vol 91 (6) ◽  
pp. 971-984
Author(s):  
A. O. Kurskova ◽  
V. V. Dotsenko ◽  
K. A. Frolov ◽  
N. A. Aksenov ◽  
I. V. Aksenova ◽  
...  
Keyword(s):  
New Methods ◽  
Methods Of Synthesis

Advances in lead-free pyroelectric materials: a comprehensive review

2020 ◽  
Vol 8 (5) ◽  
pp. 1494-1516 ◽  
Author(s):  
Hongying He ◽  
Xin Lu ◽  
Emil Hanc ◽  
Chao Chen ◽  
Hao Zhang ◽  
...  
Keyword(s):  
Potential Energy ◽  
Temperature Change ◽  
Electrical Response ◽  
Functional Materials ◽  
Lead Free ◽  
Comprehensive Review ◽  
Different Types

Pyroelectric materials are important functional materials that can generate an electrical response upon a temperature change. In recent years, significant advances have been achieved in different types of lead-free pyroelectrics and are rising to potential energy-related applications.

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