scholarly journals Willingness to Participate in a National Precision Medicine Cohort: Attitudes of Chronic Kidney Disease Patients at a Cleveland Public Hospital

2018 ◽  
Vol 8 (3) ◽  
pp. 21 ◽  
Author(s):  
Jessica Cooke Bailey ◽  
Dana Crawford ◽  
Aaron Goldenberg ◽  
Anne Slaven ◽  
Julie Pencak ◽  
...  
2019 ◽  
Vol 171 (9) ◽  
pp. 659 ◽  
Author(s):  
Y. Dana Neugut ◽  
Sumit Mohan ◽  
Ali G. Gharavi ◽  
Krzysztof Kiryluk

2016 ◽  
Vol 26 (2) ◽  
pp. 101-107 ◽  
Author(s):  
Ling Sun ◽  
Lu-Xi Zou ◽  
Mao-Jie Chen

2020 ◽  
Vol 20 (2) ◽  
Author(s):  
Maryatun Hasan

Abstrak. Penyakit ginjal kronis (PGK) merupakan penyakit yang dapat mengakibatkan penderitanya mengalami stress jangka panjang dan akhirnya bermanifestasi menjadi depresi. Depresi yang ditimbulkan dapat mempengaruhi perilaku pasien dalam hal pengaturan cairan sehingga dapat berakibat terhadap peningkatan Interdialytic Weight Gain (IDWG). Jika IDWG meningkat maka akan menimbulkan komplikasi yang dapat menghambat keberhasilan terapi hemodialisis.  Penelitian ini bertujuan untuk mengetahui gambaran tingkat depresi terhadap terjadinya peningkatan Interdialytic Weight Gain pada pasien PGK yang menjalani hemodialisis di RSUDZA Banda Aceh. Jenis penelitian ini adalah deskriptif analitik dengan pendekatan cross sectional. Pengumpulan data dilakukan pada bulan Desember 2019 menggunakan teknik accidental sampling dengan responden adalah pasien di unit hemodialisis RSUDZA Banda Aceh. Pengumpulan data dilakukan dengan menggunakan kuesioner Hamilton Rating Scale for Depression kemudian dilakukan analisis univariat untuk mengatahui gambaran dari penelitian dan bivariat dengan menggunakan uji korelasi Spearman. Berdasarkan hasil analisis statistik dengan menggunakan uji Spearman, didapatkan p value sebesar 0,000 (p0,05) dengan koefisien korelasi Spearman sebesar 0,729. Hal ini menunjukkan adanya hubungan yang signifikan antara tingkat depresi dengan peningkatan IDWG pada pasien PGK yang menjalani hemodialisis di RSUDZA Banda Aceh.Kata Kunci: Penyakit Ginjal Kronis, Hemodialisis, Depresi, Interdialytic Weight GainAbstract. Chronic kidney diasease (CKD) might cause stress which generally leads to depression. Depression is correlated to significant impairment in a patient's daily life, such as excessive Interdialytic Weight Gain (IDWG) caused by an overload of fluids. Excessive Interdialytic Weight Gain might also cause other complications that are able to interfere the process of hemodialysis therapy. The objective of this research was to identify the overview of and the correlation between depression types and Interdialytic Weight Gain (IDWG) of the chronic kidney disease patients undergoing hemodialysis therapy in dr. Zainoel Abidin Regional Public Hospital of Banda Aceh. This descriptive analytical research was conducted by means of a cross-sectional study approach. The data were collected in December 2019 by using an accidental sampling technique. The data were collected by distributing the Hamilton Rating Scale for Depression. Those data were then analyzed by using a univariate data analysis and a bivariate data analysis, especially the Spearman Correlation Coefficient. Based on the statistical analysis with the Spearman test, p-value of 0.000 (p0.05) with a Spearmen Correlation Coefficient of 0.729 was found. Hence, a significant correlation between depression levels or types and IDWG in chronic kidney disease patients undergoing hemodialysis in dr. Zainoel Abidin Regional Public Hospital of Banda Aceh was indicated.Keywords: Chronic Kidney Disease, hemodialysis, Depression, Interdialytic Weight Gain


2019 ◽  
Vol 41 (4) ◽  
pp. 501-508
Author(s):  
Edward Mezones-Holguin ◽  
Roberto Niño-Garcia ◽  
Percy Herrera-Añazco ◽  
Álvaro Taype-Rondan ◽  
Josmel Pacheco-Mendoza ◽  
...  

Abstract Objective: To evaluate the association between dysnatremias or dyschloremias and mortality during hospitalization in patients with acute kidney injury (AKI) or chronic kidney disease (CKD) undergoing acute hemodialysis. Methods: We carried out a retrospective cohort study on adult patients undergoing acute hemodialysis with AKI or CKD diagnosis at a public hospital in Lima, Peru. Dysnatremias were categorized as hyponatremia (Na < 135mmol/L) or hypernatremia (Na > 145mmol/L), and dyschloremias were defined as hypochloremia (Cl < 98 mmol/L) or hyperchloremia (Cl > 109mmol/L). The outcome of interest was mortality during hospitalization. We performed generalized lineal Poisson family models with bias-corrected and accelerated non-parametric bootstrap to estimate the risk ratios at crude (RR) and adjusted analysis (aRR) by gender, age, HCO3 (for all patients) and Liaño score (only for AKI) with CI95%. Results: We included 263 patients (mean age: 54.3 years, females: 43%): 191 with CKD and 72 with AKI. Mortality was higher in patients with AKI (59.7%) than in patients with CKD (14.1%). In overall, patients with hypernatremia had a higher mortality during hospitalization compared to those who had normal sodium values (aRR: 1.82, 95% CI: 1.17-2.83); patients with hyponatremia did not have different mortality (aRR: 0.19, 95% CI: 0.69-2.04). We also found that hyperchloremia (aRR: 1.35, 95% CI: 0.83-2.18) or hypochloremia (aRR: 0.66, 95% CI: 0.30-14.78) did not increase mortality in comparison to normal chloride values. No association between dysnatremias or dyschloremias and mortality during hospitalization was found in CKD and AKI subgroups. Conclusions: In our exploratory analysis, only hypernatremia was associated with mortality during hospitalization among patients with AKI or CKD undergoing acute hemodialysis.


PLoS ONE ◽  
2020 ◽  
Vol 15 (12) ◽  
pp. e0243027
Author(s):  
Roopa Kalyanaraman Marcello ◽  
Johanna Dolle ◽  
Sheila Grami ◽  
Richard Adule ◽  
Zeyu Li ◽  
...  

Background New York City (NYC) bore the greatest burden of COVID-19 in the United States early in the pandemic. In this case series, we describe characteristics and outcomes of racially and ethnically diverse patients tested for and hospitalized with COVID-19 in New York City’s public hospital system. Methods We reviewed the electronic health records of all patients who received a SARS-CoV-2 test between March 5 and April 9, 2020, with follow up through April 16, 2020. The primary outcomes were a positive test, hospitalization, and death. Demographics and comorbidities were also assessed. Results 22254 patients were tested for SARS-CoV-2. 13442 (61%) were positive; among those, the median age was 52.7 years (interquartile range [IQR] 39.5–64.5), 7481 (56%) were male, 3518 (26%) were Black, and 4593 (34%) were Hispanic. Nearly half (4669, 46%) had at least one chronic disease (27% diabetes, 30% hypertension, and 21% cardiovascular disease). Of those testing positive, 6248 (46%) were hospitalized. The median age was 61.6 years (IQR 49.7–72.9); 3851 (62%) were male, 1950 (31%) were Black, and 2102 (34%) were Hispanic. More than half (3269, 53%) had at least one chronic disease (33% diabetes, 37% hypertension, 24% cardiovascular disease, 11% chronic kidney disease). 1724 (28%) hospitalized patients died. The median age was 71.0 years (IQR 60.0, 80.9); 1087 (63%) were male, 506 (29%) were Black, and 528 (31%) were Hispanic. Chronic diseases were common (35% diabetes, 37% hypertension, 28% cardiovascular disease, 15% chronic kidney disease). Male sex, older age, diabetes, cardiac history, and chronic kidney disease were significantly associated with testing positive, hospitalization, and death. Racial/ethnic disparities were observed across all outcomes. Conclusions and relevance This is the largest and most racially/ethnically diverse case series of patients tested and hospitalized for COVID-19 in New York City to date. Our findings highlight disparities in outcomes that can inform prevention and testing recommendations.


2019 ◽  
Vol 1 (1) ◽  
pp. 19-24
Author(s):  
Nala Fidarotul Ulya ◽  
Gilang Kusdinar ◽  
Kurniawan Santoso

Chronic kidney disease (CKD) is kidney damage that occurs for more than 3 months with a glomerular filtration rate of less than 60 ml/sec/ 1.73 m2. WHO estimates that in Indonesia, there will be an increase in PGK in 1995-2025 by 41.4%. Over the past 40 years, Creatinine serum has become the most common and cheap serum marker for kidney function. One of the most common complications in patients with PGK is anemia. Anemia in PGK can be caused by several factors such as EPO deficiency, iron deficiency, etc. One of the usual parameters checking is the iron status of TIBC. This study aims to determine the relationship of serum Creatinine level with TIBC in chronic kidney patients in Gambiran regional public hospital Kediri and sampling taken by quota sampling. The study used cross-sectional using Rank Spearman statistic test. This test is used for abnormally distributed data types. The measured variable was serum Creatinine level with TIBC. The results of this study indicate that the value of p = (0.000)> α = (0.05), so H1 rejected and H0 accepted, then there is no relationship between serum Creatinine levels with TIBC in patients with chronic kidney disease in Gambiran Hospital Kediri.


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