Urinary Proteomics and Precision Medicine for Chronic Kidney Disease: Current Status and Future Perspectives

2019 ◽  
Vol 13 (2) ◽  
pp. 1800176 ◽  
Author(s):  
Frederik Persson ◽  
Peter Rossing
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Precision Medicine ◽  
Current Status ◽  
Future Perspectives ◽  
Urinary Proteomics

scholarly journals Cases in Precision Medicine: APOL1 and Genetic Testing in the Evaluation of Chronic Kidney Disease and Potential Transplant

2019 ◽  
Vol 171 (9) ◽  
pp. 659 ◽  
Author(s):  
Y. Dana Neugut ◽  
Sumit Mohan ◽  
Ali G. Gharavi ◽  
Krzysztof Kiryluk
Keyword(s):  
Chronic Kidney Disease ◽  
Genetic Testing ◽  
Kidney Disease ◽  
Precision Medicine

scholarly journals Make Precision Medicine Work for Chronic Kidney Disease

2016 ◽  
Vol 26 (2) ◽  
pp. 101-107 ◽  
Author(s):  
Ling Sun ◽  
Lu-Xi Zou ◽  
Mao-Jie Chen
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Precision Medicine

Urinary proteomics in the assessment of chronic kidney disease

2011 ◽  
Vol 20 (6) ◽  
pp. 654-661 ◽  
Author(s):  
William Mullen ◽  
Christian Delles ◽  
Harald Mischak
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Urinary Proteomics

scholarly journals Fine Particulate Matter (PM2.5) and Chronic Kidney Disease

2021 ◽  
pp. 183-215
Author(s):  
Yilin Zhang ◽  
Dongwei Liu ◽  
Zhangsuo Liu
Keyword(s):  
Chronic Kidney Disease ◽  
Particulate Matter ◽  
Kidney Disease ◽  
Fine Particulate Matter ◽  
Kidney Damage ◽  
Current Status ◽  
Global Database ◽  
Government Organizations ◽  
Scientific Papers ◽  
The Impact

AbstractThe impact of ambient particulate matter (PM) on public health has become a great global concern, which is especially prominent in developing countries. For health purposes, PM is typically defined by size, with the smaller particles having more health impacts. Particles with a diameter <2.5 μm are called PM2.5. Initial research studies have focused on the impact of PM2.5 on respiratory and cardiovascular diseases; nevertheless, an increasing number of data suggested that PM2.5 may affect every organ system in the human body, and the kidney is of no exception. The kidney is vulnerable to particulate matter because most environmental toxins are concentrated by the kidney during filtration. According to the high morbidity and mortality related to chronic kidney disease, it is necessary to determine the effect of PM2.5 on kidney disease and its mechanism that needs to be identified. To understand the current status of PM2.5 in the atmosphere and their potential harmful kidney effects in different regions of the world this review article was prepared based on peer-reviewed scientific papers, scientific reports, and database from government organizations published after the year 1998. In this review, we focus on the worldwide epidemiological evidence linking PM2.5 with chronic kidney disease and the effect of PM2.5 on the chronic kidney disease (CKD) progression. At the same time, we also discuss the possible mechanisms of PM2.5 exposure leading to kidney damage, in order to emphasize the contribution of PM2.5 to kidney damage. A global database on PM2.5 and kidney disease should be developed to provide new ideas for the prevention and treatment of kidney disease.

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