scholarly journals Evaluation of the Adenocarcinoma-Associated Gene AGR2 and the Intestinal Stem Cell Marker LGR5 as Biomarkers in Colorectal Cancer

2012 ◽  
Vol 13 (4) ◽  
pp. 4367-4387 ◽  
Author(s):  
Manuel Valladares-Ayerbes ◽  
Moisés Blanco-Calvo ◽  
Margarita Reboredo ◽  
María J. Lorenzo-Patiño ◽  
Pilar Iglesias-Díaz ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Stem Cell ◽  
Stem Cell Marker ◽  
Intestinal Stem Cell ◽  
Cell Marker

scholarly journals Clinicopathologic and prognostic significance of LGR5, a cancer stem cell marker in patients with colorectal cancer

2019 ◽  
Vol 8 (4) ◽  
pp. CRC11 ◽  
Author(s):  
Chukwuemeka Ihemelandu ◽  
Aisha Naeem ◽  
Erika Parasido ◽  
Deborah Berry ◽  
Krysta Chaldekas ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Stem Cell ◽  
Cancer Stem Cell ◽  
Prognostic Marker ◽  
Prognostic Significance ◽  
Stem Cell Marker ◽  
Cancer Stem Cell Marker ◽  
Cell Marker ◽  
Independent Prognostic Marker ◽  
Lgr5 Expression

Aim: To analyze the clinicopathologic and prognostic significance of Leucine-rich repeat-containing G-protein-coupled receptor 5 (LGR5), a cancer stem cell marker expression in a cohort of colorectal cancer patients (CRC). Patients & methods: A total of 76 formalin-fixed paraffin-embedded tissue blocks of primary or metastatic tumors from 49 CRC patients were collected for duration 2009–2015. LGR5 expression was assessed through immunohistochemical staining of a tissue microarray. Results: LGR5 was significantly over expressed in CRC tissue samples and found to be a statistically significant independent prognostic marker for an improved overall survival. Conclusion: LGR5 expression was higher in colorectal cancer than in normal tissue. LGR5 was an independent prognostic marker for better clinical outcomes and might be used as a potential therapeutic target in CRCs.

Prominin1 (CD133) as an Intestinal Stem Cell Marker: Promise and Nuance

2009 ◽  
Vol 136 (7) ◽  
pp. 2051-2054 ◽  
Author(s):  
Robert K. Montgomery ◽  
Ramesh A. Shivdasani
Keyword(s):  
Stem Cell ◽  
Stem Cell Marker ◽  
Intestinal Stem Cell ◽  
Cell Marker

scholarly journals Expression and clinical significance of colorectal cancer stem cell marker EpCAMhigh/CD44+ in colorectal cancer

2014 ◽  
Vol 7 (5) ◽  
pp. 1544-1548 ◽  
Author(s):  
DAN LIU ◽  
JINGHUA SUN ◽  
JINMING ZHU ◽  
HUAN ZHOU ◽  
XIAN ZHANG ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Stem Cell ◽  
Cancer Stem Cell ◽  
Clinical Significance ◽  
Stem Cell Marker ◽  
Cancer Stem Cell Marker ◽  
Cell Marker

scholarly journals Intestinal Stem Cell Marker ASCL2 is a Novel Prognostic Predictor in Esophageal Adenocarcinoma

Cureus ◽  
2022 ◽  
Author(s):  
Yukiko Shibahara ◽  
Osvaldo Espin-Garcia ◽  
James Conner ◽  
Jessica Weiss ◽  
Mathieu Derouet ◽  
...  
Keyword(s):  
Stem Cell ◽  
Esophageal Adenocarcinoma ◽  
Stem Cell Marker ◽  
Intestinal Stem Cell ◽  
Cell Marker ◽  
Prognostic Predictor

The Intestinal Stem Cell Marker SMOC2 Is an Independent Prognostic Marker Associated With Better Survival in Gastric Cancer

2021 ◽  
Vol 41 (7) ◽  
pp. 3689-3698
Author(s):  
CHANG LIM HYUN ◽  
SUNG JOON PARK ◽  
HYE SUNG KIM ◽  
HYUN JOO SONG ◽  
HEUNG UP KIM ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Stem Cell ◽  
Prognostic Marker ◽  
Stem Cell Marker ◽  
Intestinal Stem Cell ◽  
Cell Marker ◽  
Independent Prognostic Marker
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